{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T01:15:14Z","timestamp":1788225314543,"version":"build-2803163510"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In all healthcare systems, and particularly those that are resource limited, using diagnostic techniques efficiently is essential. According to consensus guidelines, standard computed tomography (CT) imaging without positron emission tomography (PET) is usually sufficient for the management of metastatic colorectal cancer (mCRC). This retrospective national cohort study evaluated the use of PET in mCRC management among members of Clalit Health Services (CHS, the largest Israeli health maintenance organization covering &amp;gt;50% of the Israeli population), utilizing the CHS central database. The cohort included CHS members diagnosed with mCRC between 2017 and 2022 (N\u2009=\u2009998). The median number of PETs performed per patient was 5. Overall, during the follow-up period (up to 10\/2024), 44% of patients underwent &amp;gt;5PETs, and the median number of PETs performed per patient per year was 2.2. In conclusion, our study identified a substantial overuse of PET in the management of mCRC in Israel, marking a divergence from clinical guidelines. More research is needed to assess this in other diseases and in other countries\/regions.<\/jats:p>","DOI":"10.1093\/oncolo\/oyag336","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:51:30Z","timestamp":1787226690000},"source":"Crossref","is-referenced-by-count":0,"title":["Use and overuse of positron emission tomography for patients with metastatic colorectal cancer"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8082-9622","authenticated-orcid":false,"given":"Daniel A","family":"Goldstein","sequence":"first","affiliation":[{"name":"Center for Cancer Economics, Davidoff Cancer Center, Rabin Medical Center , Petah Tikva, 4941492,","place":["Israel"]},{"name":"Gray Faculty of Medical and Health Sciences, Tel Aviv University , Tel Aviv, 6997801,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3539-1940","authenticated-orcid":false,"given":"Roi","family":"Tschernichovsky","sequence":"additional","affiliation":[{"name":"Davidoff Cancer Center, Rabin Medical Center , Petah Tikva, 4941492,","place":["Israel"]},{"name":"Department of Molecular Cell Biology, Weizmann Institute of Science , Rehovot, 7632701,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talish","family":"Razi","sequence":"additional","affiliation":[{"name":"Clalit Health Service , Tel Aviv, 6468211,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6058-8665","authenticated-orcid":false,"given":"Ronen","family":"Arbel","sequence":"additional","affiliation":[{"name":"Clalit Health Service , Tel Aviv, 6468211,","place":["Israel"]},{"name":"Sapir College , Sderot, 7956000,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doron","family":"Netzer","sequence":"additional","affiliation":[{"name":"Clalit Health Service , Tel Aviv, 6468211,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026083120464713500_oyag336-B1","year":"2026"},{"key":"2026083120464713500_oyag336-B2","doi-asserted-by":"publisher","first-page":"e000391","DOI":"10.1136\/bmjonc-2024-000391","article-title":"Choosing wisely in oncology: are guidelines effective at preventing unnecessary diagnostics? The example of surveillance positron emission tomography for patients with localised colorectal cancer","volume":"3","author":"Goldstein","year":"2024","journal-title":"BMJ Oncol"},{"key":"2026083120464713500_oyag336-B3","year":"2025"},{"key":"2026083120464713500_oyag336-B4","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1056\/NEJMoa2204919","article-title":"Nirmatrelvir use and severe covid-19 outcomes during the omicron surge","volume":"387","author":"Arbel","year":"2022","journal-title":"N Engl J Med"},{"key":"2026083120464713500_oyag336-B5","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1056\/NEJMoa2119497","article-title":"Effectiveness of the BNT162b2 vaccine after recovery from covid-19","volume":"386","author":"Hammerman","year":"2022","journal-title":"N Engl J Med"},{"key":"2026083120464713500_oyag336-B6","doi-asserted-by":"publisher","first-page":"5988","DOI":"10.21037\/apm-20-919","article-title":"The multidisciplinary management of oligometastases from colorectal cancer: a narrative review","volume":"10","author":"Chandy","year":"2021","journal-title":"Ann Palliat Med"},{"key":"2026083120464713500_oyag336-B7","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1056\/NEJMp1806371","article-title":"Beyond nudges - when improving health calls for greater assertiveness","volume":"380","author":"Ubel","year":"2019","journal-title":"N Engl J Med"},{"key":"2026083120464713500_oyag336-B8","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1136\/bmjqs-2019-010756","article-title":"Limiting surveillance imaging for patients with lymphoma in remission: a mixed methods study leading to a choosing wisely recommendation","volume":"30","author":"Paltiel","year":"2021","journal-title":"BMJ Qual Saf"}],"container-title":["The Oncologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/oncolo\/advance-article-pdf\/doi\/10.1093\/oncolo\/oyag336\/70760111\/oyag336.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/31\/9\/oyag336\/70760111\/oyag336.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/oncolo\/article-pdf\/31\/9\/oyag336\/70760111\/oyag336.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:46:51Z","timestamp":1788223611000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/oncolo\/article\/doi\/10.1093\/oncolo\/oyag336\/8767984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,8,6]]}},"URL":"https:\/\/doi.org\/10.1093\/oncolo\/oyag336","relation":{},"ISSN":["1083-7159","1549-490X"],"issn-type":[{"value":"1083-7159","type":"print"},{"value":"1549-490X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,8,6]]},"article-number":"oyag336"}}