{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T20:22:37Z","timestamp":1789503757409,"version":"build-2803163510"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T00:00:00Z","timestamp":1587686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Large vestibular schwannomas (VSs) with brainstem compression are generally reserved for surgical resection. Surgical aggressiveness must be balanced with morbidity from cranial nerve injury. The purpose of the present investigation is to evaluate the clinical presentation, management modality, and patient outcomes following near total resection (NTR) vs gross total resection (GTR) of large VSs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To assess facial nerve outcome differences between GTR and NTR patient cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Between January 2010 and March 2018, a retrospective chart review was completed to capture patients continuously who had VSs with Hannover grades T4a and T4b. NTR was decided upon intraoperatively. Primary data points were collected, including preoperative symptoms, tumor size, extent of resection, and postoperative neurological outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 37 patients underwent surgery for treatment of large and giant (grade 4a and 4b) VSs. Facial nerve integrity was preserved in 36 patients (97%) at the completion of surgery. A total of 27 patients underwent complete resection, and 10 had near total (&gt;95%) resection. Among patients with GTR, 78% (21\/27) had House-Brackmann (HB) grade I-II facial nerve function at follow-up, whereas 100% (10\/10) of the group with NTR had HB grade I-II facial nerve function. Risk of meningitis, cerebrospinal fluid leak, and sinus thromboses were not statistically different between the 2 groups. There was no stroke, brainstem injury, or death. The mean follow-up was 36 mo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>NTR seems to offer a benefit in terms of facial nerve functional outcome compared to GTR in surgical management of large VSs without significant risk of recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opaa056","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T12:55:55Z","timestamp":1587732955000},"page":"414-421","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Near Total Versus Gross Total Resection of Large Vestibular Schwannomas: Facial Nerve Outcome"],"prefix":"10.1227","volume":"19","author":[{"given":"Julia R","family":"Schneider","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, North Shore University Hospital, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrit K","family":"Chiluwal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, North Shore University Hospital, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orseola","family":"Arapi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, North Shore University Hospital, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Kwan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, North Shore University Hospital, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir R","family":"Dehdashti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, North Shore University Hospital, Manhasset, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"bib1-20240909","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.wneu.2016.06.119","article-title":"Surgical treatment of giant vestibular schwannomas: facial nerve outcome and tumor control","volume":"94","author":"Zhang","year":"2016","journal-title":"World Neurosurg"},{"issue":"2","key":"bib2-20240909","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.anorl.2010.03.003","article-title":"Surgical treatment of large vestibular schwannomas (stages III and IV)","volume":"127","author":"Talfer","year":"2010","journal-title":"Eur Ann Otorhinolaryngol Head Neck 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