{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:11:51Z","timestamp":1790986311805,"version":"4.1.0"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/ mailto:journals.permissions@oup.com"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Intraoperative cone-beam computed tomography (iCBCT) allows for rapid 3-dimensional imaging. However, it is currently unknown whether this imaging technique offers sufficient accuracy for stereotactic registration during deep brain stimulation (DBS) procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To determine the accuracy of iCBCT, with the O-arm O2 (Medtronic), for stereotactic registration by comparing this modality to stereotactic magnetic resonance imaging (MRI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>All DBS patients underwent a preoperative non-stereotactic 3 Tesla MRI, stereotactic 1.5 Tesla MRI, stereotactic O-arm iCBCT, postimplantation O-arm iCBCT, and postoperative conventional multidetector computed tomography (CT) scan. We compared stereotactic (X, Y, and Z) coordinates of the anterior commissure (AC), the posterior commissure (PC), and midline reference (MR) between stereotactic MRI and iCBCT. For localisation comparison of electrode contacts, stereotactic coordinates of electrode tips were compared between the postoperative multidetector CT and iCBCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 20 patients were evaluated. The average absolute difference in stereotactic coordinates of AC, PC, and MR was 0.4\u00a0\u00b1\u00a00.4 mm for X, 0.4\u00a0\u00b1\u00a00.4 mm for Y, and 0.7\u00a0\u00b1 0.5 mm for Z. The average absolute difference in X-, Y-, and Z-coordinates for electrode localisation (N\u00a0=\u00a034) was 0.3\u00a0\u00b1\u00a00.3 mm, 0.6\u00a0\u00b1\u00a00.3 mm, and 0.6\u00a0\u00b1\u00a00.6 mm. These differences were small enough not to be considered clinically relevant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Stereotactic MRI and O-arm iCBCT yield comparable coordinates in pre- and postoperative imaging. Differences found are below the threshold of clinical relevance. Intraoperative O-arm CBCT offers rapid stereotactic registration and evaluation of electrode placement. This increases patient comfort and neurosurgical workflow efficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opaa110","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T23:31:46Z","timestamp":1589239906000},"page":"E224-E229","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":23,"title":["Implementation of Intraoperative Cone-Beam Computed Tomography (O-arm) for Stereotactic Imaging During Deep Brain Stimulation Procedures"],"prefix":"10.1227","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6112-411X","authenticated-orcid":false,"given":"Rozemarije A","family":"Holewijn","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Amsterdam University Medical Centers, Academic Medical Center (AMC), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Bot","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Amsterdam University Medical Centers, Academic Medical Center (AMC), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pepijn","family":"van den Munckhof","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Amsterdam University Medical Centers, Academic Medical Center (AMC), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P Richard","family":"Schuurman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Amsterdam University Medical Centers, Academic Medical Center (AMC), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,9]]},"reference":[{"issue":"1","key":"bib1-20240909","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1474-4422(12)70264-8","article-title":"Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial","volume":"12","author":"Odekerken","year":"2013","journal-title":"Lancet Neurol"},{"issue":"9","key":"bib2-20240909","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S1474-4422(14)70143-7","article-title":"Pallidal neurostimulation in patients with medication-refractory cervical dystonia: a randomised, sham-controlled trial","volume":"13","author":"Volkmann","year":"2014","journal-title":"Lancet Neurol"},{"issue":"8","key":"bib3-20240909","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/mds.22059","article-title":"Long-term follow-up of thalamic stimulation versus thalamotomy for tremor suppression","volume":"23","author":"Schuurman","year":"2008","journal-title":"Mov Disord"},{"issue":"10","key":"bib4-20240909","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/archgenpsychiatry.2010.122","article-title":"Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder","volume":"67","author":"Denys","year":"2010","journal-title":"Arch Gen Psychiatry"},{"issue":"11","key":"bib5-20240909","first-page":"647","article-title":"Prevalent placement error of deep brain stimulation electrode in movement disorders (technical considerations)","volume":"118","author":"Kloc","year":"2017","journal-title":"Bratisl Lek Listy"},{"issue":"3","key":"bib6-20240909","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1159\/000475672","article-title":"Accuracy of intraoperative computed tomography during deep brain stimulation procedures: comparison with postoperative magnetic resonance imaging","volume":"95","author":"Bot","year":"2017","journal-title":"Stereotact Funct Neurosurg"},{"issue":"6","key":"bib7-20240909","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.neuchi.2014.05.005","article-title":"Intraoperative 3D imaging control during subthalamic deep brain stimulation procedures using O-arm(R) technology: experience in 15 patients","volume":"60","author":"Caire","year":"2014","journal-title":"Neurochirurgie"},{"issue":"1 Suppl Operative","key":"bib8-20240909","first-page":"47","article-title":"A quantitative assessment of the accuracy and reliability of O-arm images for deep brain stimulation surgery","volume":"72","author":"Holloway","year":"2013","journal-title":"Neurosurgery"},{"issue":"5","key":"bib9-20240909","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1159\/000375178","article-title":"Analysis of stereotactic accuracy in patients undergoing deep brain stimulation using Nexframe and the Leksell Frame","volume":"93","author":"Bot","year":"2015","journal-title":"Stereotact Funct Neurosurg"},{"issue":"1","key":"bib10-20240909","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1186\/s13063-017-2136-8","article-title":"General Anesthesia versus Local Anesthesia in StereotaXY (GALAXY) for Parkinson's disease: study protocol for a randomized controlled trial","volume":"18","author":"Holewijn","year":"2017","journal-title":"Trials"},{"issue":"2","key":"bib11-20240909","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000280823","article-title":"Intraoperative use of the Medtronic O-arm for deep brain stimulation procedures","volume":"88","author":"Caire","year":"2010","journal-title":"Stereotact Funct Neurosurg"},{"issue":"1","key":"bib12-20240909","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1227\/NEU.0000000000001326","article-title":"Stereotactic Accuracy and surgical utility of the O-arm in deep brain stimulation surgery","volume":"13","author":"Carlson","year":"2017","journal-title":"Oper Neurosurg"},{"issue":"6","key":"bib13-20240909","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1159\/000341699","article-title":"Stereotactic operations using the O-arm","volume":"90","author":"Katisko","year":"2012","journal-title":"Stereotact Funct Neurosurg"},{"issue":"Suppl 19","key":"bib14-20240909","doi-asserted-by":"crossref","first-page":"S551","DOI":"10.4103\/2152-7806.187534","article-title":"The pros and cons of intraoperative CT scan in evaluation of deep brain stimulation lead implantation: A retrospective study","volume":"7","author":"Servello","year":"2016","journal-title":"Surg Neurol Int"},{"issue":"1 Suppl Operative","key":"bib15-20240909","first-page":"114","article-title":"Intraoperative computed tomography for deep brain stimulation surgery: technique and accuracy assessment","volume":"68","author":"Shahlaie","year":"2011","journal-title":"Neurosurgery"},{"key":"bib16-20240909","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jocn.2015.06.036","article-title":"Accuracy and safety of targeting using intraoperative \u201cO-arm\u201d during placement of deep brain stimulation electrodes without electrophysiological recordings","volume":"27","author":"Sharma","year":"2016","journal-title":"J Clin Neurosci"},{"issue":"4","key":"bib17-20240909","first-page":"305","article-title":"Dosimetric characterization of a cone-beam O-arm imaging system","volume":"17","author":"Zhang","year":"2009","journal-title":"J Xray Sci Technol"},{"issue":"6","key":"bib19-20240909","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/ner.12744","article-title":"The safety and efficacy of using the O-arm intraoperative imaging system for deep brain stimulation lead implantation","volume":"21","author":"Frizon","year":"2018","journal-title":"Neuromodulation"}],"container-title":["Operative Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ons\/article-pdf\/19\/3\/E224\/33742274\/opaa110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ovid.com\/10.1093\/ons\/opaa110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:56:13Z","timestamp":1786121773000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1093\/ons\/opaa110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,11]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1093\/ons\/opaa110","relation":{},"ISSN":["2332-4252","2332-4260"],"issn-type":[{"value":"2332-4252","type":"print"},{"value":"2332-4260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,11]]},"assertion":[{"value":"2019-07-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}