{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:47:53Z","timestamp":1792176473729,"version":"4.4.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Trigeminal neuralgia (TN) refractory to medical management is often treated with microvascular decompression (MVD) involving the intracranial placement of Teflon. The placement of Teflon is an effective treatment, but does apply distributed pressure to the nerve and has been associated with pain recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To report the rate of postoperative pain recurrence in TN patients who underwent MVD surgery using a transposition technique with fibrin glue without Teflon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Patients were eligible for our study if they were diagnosed with TN, did not have multiple sclerosis, and had an offending vessel that was identified and transposed with fibrin glue at our institution. All eligible patients were given a follow-up survey. We used a Kaplan-Meier (KM) model to estimate overall pain recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 102 patients met inclusion criteria, of which 85 (83%) responded to our survey. Overall, 76 (89.4%) participants responded as having no pain recurrence. Approximately 1-yr pain-free KM estimates were 94.1% (n\u00a0=\u00a083), 5-yr pain-free KM estimates were 94.1% (n\u00a0=\u00a053), and 10-yr pain-free KM estimates were 83.0% (n\u00a0=\u00a023).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Treatment for TN with an MVD transposition technique using fibrin glue may avoid some cases of pain recurrence. The percentage of patients in our cohort who remained pain free at a maximum of 17 yr follow-up is on the high end of pain-free rates reported by MVD studies using Teflon. These results indicate that a transposition technique that emphasizes removing any compression near the trigeminal nerve root provides long-term pain-free rates for patients with TN.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opaa413","type":"journal-article","created":{"date-parts":[[2021,3,14]],"date-time":"2021-03-14T20:01:33Z","timestamp":1615752093000},"page":"397-405","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":22,"title":["Microvascular Transposition Without Teflon: A Single Institution's 17-Year Experience Treating Trigeminal Neuralgia"],"prefix":"10.1227","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6968-2829","authenticated-orcid":false,"given":"Andrew R","family":"Pines","sequence":"first","affiliation":[{"name":"Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J","family":"Butterfield","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research, Division of Biostatistics Clinic, Scottsdale, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn L","family":"Turcotte","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose O","family":"Garcia","sequence":"additional","affiliation":[{"name":"Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel","family":"De Lucia","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily J","family":"Algier","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naresh P","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,4]]},"reference":[{"issue":"5-6","key":"bib1-20251027","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1159\/000110284","article-title":"Epidemiology and clinical features of idiopathic trigeminal neuralgia and glossopharyngeal neuralgia: similarities and differences, Rochester, Minnesota, 1945-1984","volume":"10","author":"Katusic","year":"1991","journal-title":"Neuroepidemiology"},{"issue":"1","key":"bib2-20251027","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0304-3959(98)00145-6","article-title":"A prospective, longitudinal study on patients with trigeminal neuralgia who underwent radiofrequency thermocoagulation of the Gasserian ganglion","volume":"79","author":"Zakrzewska","year":"1999","journal-title":"Pain"},{"issue":"3","key":"bib3-20251027","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0304-3959(01)00406-7","article-title":"Long-term cohort study comparing medical (oxcarbazepine) and surgical management of intractable trigeminal neuralgia","volume":"95","author":"Zakrzewska","year":"2002","journal-title":"Pain"},{"issue":"3","key":"bib4-20251027","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1533-2500.2006.00079.x","article-title":"Patient burden of trigeminal neuralgia: results from a cross-sectional survey of health state impairment and treatment patterns in six European countries","volume":"6","author":"Tolle","year":"2006","journal-title":"Pain Pract"},{"issue":"1","key":"bib5-20251027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition","volume":"38","year":"2018","journal-title":"Cephalalgia"},{"issue":"6","key":"bib6-20251027","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/(SICI)1098-2353(1997)10:6<380::AID-CA2>3.0.CO;2-T","article-title":"Neurovascular relationships in the posterior cranial fossa, with special reference to trigeminal neuralgia. 2. 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