{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:34:13Z","timestamp":1789094053005,"version":"build-2803163510"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Abstract<\/jats:title>\n \n BACKGROUND:<\/jats:bold>\n The development of cysts at the electrode lead is a rare complication of deep brain stimulation (DBS), with only 3 cases reported in the literature. A better understanding of the variable clinical presentations and courses of these cysts may help increase awareness of this potentially life-threatening complication.\n <\/jats:p>\n \n OBJECTIVE:<\/jats:bold>\n To review the clinical presentation of patients with intraparenchymal cysts following DBS implantations.\n <\/jats:p>\n \n METHODS:<\/jats:bold>\n We report 3 patients who developed a cyst along the course of the DBS lead. These patients received DBS for different indications and in different brain locations.\n <\/jats:p>\n \n RESULTS:<\/jats:bold>\n Clinical courses differed considerably with 1 asymptomatic patient followed conservatively, 1 mildly symptomatic patient who had the DBS hardware removed for insidious worsening over months, and 1 who had it emergently removed for acute development of hydrocephalus. Serial imaging revealed spontaneous reduction in cyst size over time in the asymptomatic patient, and following removal in 1 of the symptomatic patients.\n <\/jats:p>\n \n CONCLUSION:<\/jats:bold>\n This report highlights the variable clinical presentation and course of patients who develop cysts along the DBS lead. It suggests that some cases can be followed clinically without removal of hardware but that ongoing vigilance is required given the potential for serious adverse events.\n <\/jats:p>","DOI":"10.1093\/ons\/opx037","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T19:24:40Z","timestamp":1491420280000},"page":"576-580","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Intraparenchymal Cysts Following Deep Brain Stimulation: Variable Presentations and Clinical Courses"],"prefix":"10.1227","volume":"13","author":[{"given":"Kalman","family":"Katlowitz","sequence":"first","affiliation":[{"name":"Center for Neuromodulation, Depart-ment of Neurosurgery, New York Univer-sity Langone Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Pourfar","sequence":"additional","affiliation":[{"name":"Center for Neuromodulation, Depart-ment of Neurosurgery, New York Univer-sity Langone Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvi","family":"Israel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alon Y.","family":"Mogilner","sequence":"additional","affiliation":[{"name":"Center for Neuromodulation, Depart-ment of Neurosurgery, New York Univer-sity Langone Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2017,10]]},"reference":[{"issue":"1","key":"bib1-20240909","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1146\/annurev.neuro.29.051605.112824","article-title":"Deep Brain Stimulation","volume":"29","author":"Perlmutter","year":"2006","journal-title":"Annu Rev 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of deep brain stimulation for Tourette's complicated by Twiddler's Syndrome","volume":"2","author":"Pourfar","year":"2015","journal-title":"Mov Disord Clin Pract"}],"container-title":["Operative Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01787389-201710000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:49:38Z","timestamp":1786121378000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01787389-201710000-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,31]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1093\/ons\/opx037","relation":{},"ISSN":["2332-4252","2332-4260"],"issn-type":[{"value":"2332-4252","type":"print"},{"value":"2332-4260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,31]]},"assertion":[{"value":"2016-08-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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