{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:51:17Z","timestamp":1786125077548,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>High-resolution ultrasound can be used for diagnosis of carpal tunnel syndrome with an equal accuracy to electrodiagnostic studies. Up to date there has been no investigation published that examined the median nerve in a large patient cohort with recurrent or persistent symptoms. Reference and cutoff values are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To provide reference values for detection of ongoing or recurrent compression in patients with recurring or persisting symptoms in carpal tunnel syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>One hundred and sixteen patients undergoing revision decompression of the median nerve at the carpal tunnel between January 2010 and October 2015 were studied retrospectively to determine the cross-sectional area of the median nerve at the wrist by the technique of neurosonography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      In cases of insufficient primary release, the mean cross-sectional area was 20.0 mm\n                      <jats:sup>2<\/jats:sup>\n                      preop. In cases of scar or synovitis, the mean cross-sectional area was 17.0 mm\n                      <jats:sup>2<\/jats:sup>\n                      (significantly less than in cases of insufficient primary release,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .008). Compared to successfully operated patients with de novo carpal tunnel syndrome (n = 74), a cutoff value of 14.5 mm\n                      <jats:sup>2<\/jats:sup>\n                      yielded a sensitivity of 78% and a specificity of 97% to diagnose ongoing or recurrent compression in case of a typical clinical presentation of ongoing or recurrent symptoms (tested via comparison of patients who are symptom free vs patients with symptoms).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>For the first time, we provide reference values in patients with recurring or persisting symptoms in carpal tunnel syndrome based on a large patient population. Ultrasound can aid in the evaluation of patients with entrapment neuropathy of the median nerve and recurring or persisting symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opx079","type":"journal-article","created":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T05:50:58Z","timestamp":1492408258000},"page":"20-25","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Cross-sectional Area of the Median Nerve Before Revision Carpal Tunnel Release\u2014A Cross-sectional Study"],"prefix":"10.1227","volume":"14","author":[{"given":"Stephan","family":"Duetzmann","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suleyman","family":"Tas","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt, Frankfurt, 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