{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:52:22Z","timestamp":1786125142220,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Angioplasty and stenting is a recognized treatment option for patients with intracranial atherosclerosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To evaluate the long-term evolutionary luminal changes of intracranial atherosclerosis after angioplasty and stenting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>This was a retrospective study with patient consent. Eighty-two patients presenting with acute and minor cerebral ischemia due to stenosis \u226570%, who had received medical therapy with or without stenting (Wingspan), were invited. Luminal imaging was provided using 3-dimensional rotational angiography (3-DRA) at baseline and 12 mo, and cone-beam computed tomography angiography with intravenous contrast (CBCT) was provided at follow-up (median 82.4 mo [interquartile range 61.9-96.9 mo]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Thirty-six patients in the stenting group and 26 patients in the medical group were recruited and completed the study. There was no statistically significant difference in demographics between the 2 patient groups. The luminal gain at 12 or 80 mo as compared to baseline in the stenting group was significantly greater than that in the medical group (12 mo: median gain 30% vs 7.2%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001; 80 mo: median gain 42.9% vs 7.2%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .0001). Luminal loss or unchanged lumen was correlated with recurrent ischemic event. The differences in the stenosis degree assessment between CBCT and 3-DRA in the same 10 patients with or without stenting were 1.2 \u00b1 0.6% or 0.2 \u00b1 0.06%, respectively. There was a correlation between recurrent ischemic events and luminal loss.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Arterial lumen after angioplasty and stenting can probably be well maintained and delayed luminal gain does occur, long-term luminal loss is associated with recurrent ischemic events, CBCT might be useful as a less-invasive means for long-term assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opx097","type":"journal-article","created":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T06:10:00Z","timestamp":1497420600000},"page":"128-138","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Long-Term Evolutionary Change in the Lumen of Intracranial Atherosclerotic Stenosis Following Angioplasty and Stenting"],"prefix":"10.1227","volume":"14","author":[{"given":"Simon C H","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Imaging and Interventional Radiology, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"},{"name":"Vascular and Interventional Radiology Foundation Clinical Science Center, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany W W","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon S M","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwok T","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence K S","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W H","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,2]]},"reference":[{"issue":"10","key":"bib1-20240909","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1161\/STROKEAHA.109.557041","article-title":"Lesion patterns and stroke mechanisms in concurrent atherosclerosis of intracranial and extracranial vessels","volume":"40","author":"Man","year":"2009","journal-title":"Stroke"},{"issue":"3","key":"bib2-20240909","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000090791","article-title":"Is hypoperfusion an important cause of strokes? 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