{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:34:36Z","timestamp":1788280476431,"version":"build-2803163510"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T00:00:00Z","timestamp":1503360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Schwannomas of the parasellar region may arise from the trigeminal, oculomotor, trochlear, and abducens nerves.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To define the tumor origin, location, and dural relationship (extradural vs extra-intradural vs cisternal) on preoperative magnetic resonance imaging (MRI), in order to plan the best surgical approach (purely extradural vs extra-intradural).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Twenty-four patients with parasellar schwannomas who underwent surgery were retrospectively analyzed. Twenty arose from the trigeminal nerve (7 intracavernous and 13 within the Meckel's cave), 3 from the oculomotor nerve, and 1 from the abducens nerve. The preoperative identification of the tumor location (extradural vs extra-intradural vs cisternal) and the nerve of origin was defined on MR sequences. All patients were operated on through a pterional approach (extradural or extra-intradural route).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The tumor location was correctly defined on MRI in 22 out of 24 cases (92%) and the nerve of origin in 22 (92%). An extradural approach without intradural exploration was performed in all 5 intracavernous trigeminal schwannomas, in 11 out of 13 of the Meckel's cave, and in 2 schwannomas of the oculomotor nerve. Two schwannomas of the Meckel's cave with transgression of the medial dural wall, 1 of the oculomotor nerve, and the abducens nerve schwannoma required an extra-intradural approach. Complete tumor resection was obtained in 19 out of 24 cases (80%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>The pterional extradural approach is sufficient for Dolenc type I and II trigeminal schwannomas, excepting for those transgressing the inner dural layer. Schwannomas of the oculomotor and abducens nerves with cisternal location require an extradural-intradural approach.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opx174","type":"journal-article","created":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T03:59:43Z","timestamp":1503374383000},"page":"627-638","source":"Crossref","is-referenced-by-count":14,"title":["Parasellar Schwannomas: Extradural vs Extra-Intradural Surgical Approach"],"prefix":"10.1227","volume":"14","author":[{"given":"Giuseppe","family":"Mariniello","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Reproductive, and Odontostomatologic Sciences, Neurosurgical Clinic, \u201cFederico II\u201d University School of Medicine, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oreste","family":"de Divitiis","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive, and Odontostomatologic Sciences, Neurosurgical Clinic, \u201cFederico II\u201d University School of Medicine, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinando","family":"Caranci","sequence":"additional","affiliation":[{"name":"Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Dones","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive, and Odontostomatologic Sciences, Neurosurgical Clinic, \u201cFederico II\u201d University School of Medicine, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Maiuri","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive, and Odontostomatologic Sciences, Neurosurgical Clinic, \u201cFederico II\u201d University School of Medicine, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6]]},"reference":[{"issue":"3","key":"bib1-20231018","doi-asserted-by":"crossref","first-page":"231","DOI":"10.4103\/0976-3147.133566","article-title":"Intracranial nonvestibular neurinomas: young neurosurgeons' experience","volume":"5","author":"Chowdhury","year":"2014","journal-title":"J Neurosci Rural Pract"},{"issue":"4","key":"bib2-20231018","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1227\/01.NEU.0000053365.05795.03","article-title":"Trigeminal neuroma: analysis of surgical experience with 73 cases","volume":"52","author":"Goel","year":"2003","journal-title":"Neurosurgery"},{"issue":"4","key":"bib3-20231018","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s10143-007-0093-5","article-title":"Surgical treatment of trigeminal schwannomas","volume":"30","author":"Pamir","year":"2007","journal-title":"Neurosurg Rev"},{"issue":"5","key":"bib4-20231018","doi-asserted-by":"crossref","first-page":"711","DOI":"10.3171\/jns.1995.82.5.0711","article-title":"Surgical treatment of trigeminal schwannomas","volume":"82","author":"Samii","year":"1995","journal-title":"J Neurosurg"},{"issue":"1","key":"bib5-20231018","doi-asserted-by":"crossref","first-page":"43","DOI":"10.14791\/btrt.2014.2.1.43","article-title":"Oculomotor nerve schwannoma: a case report","volume":"2","author":"Cho","year":"2014","journal-title":"Brain Tumor Res Treat"},{"issue":"6","key":"bib6-20231018","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.3171\/jns.1999.91.6.1045","article-title":"En bloc resection of an intracavernous oculomotor nerve schwannoma and grafting of the oculomotor nerve with sural nerve. 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