{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:11:50Z","timestamp":1791223910054,"version":"4.1.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T00:00:00Z","timestamp":1557705600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/ mailto:journals.permissions@oup.com"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Operative Surg.","ONSURG"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>As current augmented-reality (AR) smart glasses are self-contained, powerful computers that project 3-dimensional holograms that can maintain their position in physical space, they could theoretically be used as a low-cost, stand-alone neuronavigation system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To determine feasibility and accuracy of holographic neuronavigation (HN) using AR smart glasses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We programmed a fully functioning neuronavigation system on commercially available smart glasses (HoloLens\u00ae, Microsoft, Redmond, Washington) and tested its accuracy and feasibility in the operating room. The fiducial registration error (FRE) was measured for both HN and conventional neuronavigation (CN) (Brainlab, Munich, Germany) by using point-based registration on a plastic head model. Subsequently, we measured HN and CN FRE on 3 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A stereoscopic view of the holograms was successfully achieved in all experiments. In plastic head measurements, the mean HN FRE was 7.2\u00a0\u00b1\u00a01.8 mm compared to the mean CN FRE of 1.9\u00a0\u00b1\u00a00.45 (mean difference: \u20135.3 mm; 95% confidence interval [CI]: \u20136.7 to \u20133.9). In the 3 patients, the mean HN FRE was 4.4\u00a0\u00b1\u00a02.5 mm compared to the mean CN FRE of 3.6\u00a0\u00b1\u00a00.5 (mean difference: \u20130.8 mm; 95% CI: \u20133.0 to 4.6).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Owing to the potential benefits and promising results, we believe that HN could eventually find application in operating rooms. However, several improvements will have to be made before the device can be used in clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ons\/opz094","type":"journal-article","created":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T11:19:45Z","timestamp":1557746385000},"page":"588-593","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":88,"title":["Clinical Accuracy of Holographic Navigation Using Point-Based Registration on Augmented-Reality Glasses"],"prefix":"10.1227","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6299-3859","authenticated-orcid":false,"given":"Tristan P C","family":"van Doormaal","sequence":"first","affiliation":[{"name":"Rudolf Magnus Institute of Neuroscience, Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands"},{"name":"Brain Technology Institute, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse A M","family":"van Doormaal","sequence":"additional","affiliation":[{"name":"Rudolf Magnus Institute of Neuroscience, Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands"},{"name":"Brain Technology Institute, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Mensink","sequence":"additional","affiliation":[{"name":"Brain Technology Institute, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,12]]},"reference":[{"issue":"10","key":"bib1-20240909","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1007\/s00464-016-4800-6","article-title":"Systematic review on the effectiveness of augmented reality applications in medical training","volume":"30","author":"Barsom","year":"2016","journal-title":"Surg Endosc"},{"key":"bib2-20240909","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.aanat.2017.09.011","article-title":"An augmented reality magic mirror as additive teaching device for gross anatomy","volume":"215","author":"Kugelmann","year":"2018","journal-title":"Ann Anat"},{"key":"bib3-20240909","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jocn.2016.09.002","article-title":"Utilizing virtual and augmented reality for educational and clinical enhancements in neurosurgery","volume":"35","author":"Pelargos","year":"2017","journal-title":"J Clin Neurosci"},{"issue":"1","key":"bib4-20240909","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.media.2010.07.010","article-title":"Geometrical analysis of registration errors in point-based rigid-body registration using invariants","volume":"15","author":"Shamir","year":"2011","journal-title":"Med Image 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Neurosurg"},{"issue":"1","key":"bib8-20240909","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1177\/1553350618799552","article-title":"Toward holographic-guided surgery","volume":"26","author":"Meulstee","year":"2019","journal-title":"Surg Innov"},{"issue":"5","key":"bib9-20240909","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/ons\/opx279","article-title":"Smart glasses for neurosurgical navigation by augmented reality","volume":"15","author":"Maruyama","year":"2018","journal-title":"Oper Neurosurg"}],"container-title":["Operative Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ons\/article-pdf\/17\/6\/588\/32312392\/opz094.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ovid.com\/10.1093\/ons\/opz094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:50:14Z","timestamp":1786121414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1093\/ons\/opz094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,13]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1093\/ons\/opz094","relation":{},"ISSN":["2332-4252","2332-4260"],"issn-type":[{"value":"2332-4252","type":"print"},{"value":"2332-4260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,13]]},"assertion":[{"value":"2018-08-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}