{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T07:09:30Z","timestamp":1724137770352},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T00:00:00Z","timestamp":1585785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,27]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Celiac disease (CD) is an immune enteropathy caused by sensitivity to gluten affecting one per cent of the general population. Most people with CD are asymptomatic and some may be affected from childhood. Despite the latest recommendations of paediatric gastroenterology societies, targeted screening is still uncommon in clinical paediatric settings. A poor understanding of the asymptomatic population\u2019s opinions creates obstacles for broader implementation of CD screening. This study aims to fill this gap by reporting on the knowledge and opinions of adolescents and caregivers of children on CD screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adolescents with absence of classical symptoms of CD and caregivers of presumably asymptomatic children were asked about their knowledge and opinions of CD through a self-administered questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 227 respondents including 76 adolescents and 151 caregivers. A minority of respondents (8% of caregivers and 23% of adolescents) were identified as having a CD-associated condition (such as hypothyroidism, type 1 diabetes, Down syndrome, etc.). A majority of caregivers (84%) and half of adolescents (49%) already knew about CD. Half of the respondents (46%) were in favour of screening asymptomatic paediatric populations and this agreement increased to 81.7% when they were confronted with hypothetical risks of 10%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study reveals an increased willingness to screen when participants were faced with increasing hypothetical risks. This suggests that screening recommendations targeting high-risk populations, such as those of paediatric and non-paediatric gastroenterology societies, may be more widely accepted.<\/jats:p><\/jats:sec>","DOI":"10.1093\/pch\/pxaa006","type":"journal-article","created":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T13:05:10Z","timestamp":1585832710000},"page":"e145-e151","source":"Crossref","is-referenced-by-count":1,"title":["Knowledge and opinions of asymptomatic adolescents and their caregivers on celiac disease screening"],"prefix":"10.1093","volume":"26","author":[{"given":"Jasmine","family":"Blais-Carri\u00e8re","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Centre Int\u00e9gr\u00e9 Universitaire de Sant\u00e9 et Services Sociaux de l\u2019Estrie \u2013 Centre Hospitalier Universitaire de Sherbrooke (CIUSSSE-CHUS), Sherbrooke, Qu\u00e9bec"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9lie","family":"T\u00e9tu","sequence":"additional","affiliation":[{"name":"Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS), Sherbrooke, Qu\u00e9bec"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte","family":"Moreau","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Centre Int\u00e9gr\u00e9 Universitaire de Sant\u00e9 et Services Sociaux de l\u2019Estrie \u2013 Centre Hospitalier Universitaire de Sherbrooke (CIUSSSE-CHUS), Sherbrooke, Qu\u00e9bec"},{"name":"Faculty of Medicine and Health Sciences, Universit\u00e9 de Sherbrooke, Sherbrooke, Qu\u00e9bec"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,2]]},"reference":[{"issue":"9673","key":"2021042709272119900_CIT0001","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0140-6736(09)60254-3","article-title":"Coeliac disease","volume":"373","author":"Di Sabatino","year":"2009","journal-title":"Lancet"},{"issue":"2","key":"2021042709272119900_CIT0002","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1016\/j.patbio.2011.03.004","article-title":"[Complications of celiac disease]","volume":"61","author":"Cosnes","year":"2013","journal-title":"Pathol Biol (Paris)"},{"issue":"4","key":"2021042709272119900_CIT0003","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.giec.2012.07.005","article-title":"Mortality and malignancy in celiac disease","volume":"22","author":"Ludvigsson","year":"2012","journal-title":"Gastrointest Endosc Clin N Am"},{"issue":"4","key":"2021042709272119900_CIT0004","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.giec.2012.07.002","article-title":"Celiac disease in the developing world","volume":"22","author":"Barada","year":"2012","journal-title":"Gastrointest Endosc Clin N Am"},{"issue":"7","key":"2021042709272119900_CIT0005","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/ajg.2011.21","article-title":"Screening for celiac disease in a North American population: Sequential serology and gastrointestinal symptoms","volume":"106","author":"Katz","year":"2011","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"2021042709272119900_CIT0006","doi-asserted-by":"crossref","first-page":"587","DOI":"10.3109\/07853890.2010.505931","article-title":"The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project","volume":"42","author":"Mustalahti","year":"2010","journal-title":"Ann Med"},{"issue":"10","key":"2021042709272119900_CIT0007","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1038\/ajg.2012.219","article-title":"The prevalence of celiac disease in the United States","volume":"107","author":"Rubio-Tapia","year":"2012","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"2021042709272119900_CIT0008","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1542\/peds.2008-2373","article-title":"The changing face of childhood celiac disease in North America: Impact of serological testing","volume":"124","author":"McGowan","year":"2009","journal-title":"Pediatrics"},{"key":"2021042709272119900_CIT0009","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1651-2227.1996.tb14244.x","article-title":"The coeliac iceberg in Italy. 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