{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:03:58Z","timestamp":1788552238531,"version":"build-2803163510"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,22]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Canada legalized recreational cannabis in October 2018. Cannabis is increasingly available in numerous forms\u2014especially edibles\u2014that make children vulnerable to unintentional intoxication. We sought to: determine the frequency of visits due to cannabis intoxication pre- and post-legalization; characterize the clinical features and circumstances of cannabis intoxication in the paediatric population; and create greater awareness among healthcare providers about this issue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective chart review of Emergency Department visits at the Children\u2019s Hospital of Eastern Ontario (Ottawa, ON) between March 2013 and September 2020. Inclusion criteria were: age &amp;lt;18 years; unintentional cannabis ingestion, identified by ICD-10 codes T40.7 and X42. We assessed basic demographics, clinical signs and symptoms, exposure details, investigations, and patient disposition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 37 patients (22 male) met inclusion criteria, mean age 5.9\u00b13.8 years. Most visits (32; 86%) occurred in the 2-year period after legalization. Altered levels of consciousness, lethargy\/somnolence, tachycardia, and vomiting were the most common presenting signs and symptoms. The majority of exposures were to edibles (28; 76%) in the home setting (30; 81%). Poison control and child protective services were involved in 19 (51%) and 22 (59%) of cases, respectively. Twelve patients (32%) required admission to the hospital, the majority of whom stayed &amp;lt;24 h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data confirm increased paediatric hospital visits related to unintentional cannabis exposures post-legalization. Consideration of this clinical presentation is critical for acute care providers. Advocacy for safe storage strategies and appropriate enforcement of marketing\/packaging legislation are imperative for public health policymakers.<\/jats:p><\/jats:sec>","DOI":"10.1093\/pch\/pxab090","type":"journal-article","created":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T16:40:05Z","timestamp":1655916005000},"page":"265-271","source":"Crossref","is-referenced-by-count":15,"title":["Unintentional cannabis exposures in children pre- and post-legalization: A retrospective review from a Canadian paediatric hospital"],"prefix":"10.1093","volume":"27","author":[{"given":"Alon","family":"Coret","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Ottawa , Ottawa, Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Rowan-Legg","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Ottawa , Ottawa, Ontario , 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