{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:24:13Z","timestamp":1778873053763,"version":"3.51.4"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T00:00:00Z","timestamp":1549497600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Maternal-Infant Care Research Centre"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["FRN87518"],"award-info":[{"award-number":["FRN87518"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["APR-126340"],"award-info":[{"award-number":["APR-126340"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the outcomes and resource usage of infants born at \u2264 25 weeks gestational age (GA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study of infants born between April 2009 and September 2011 at \u2264 25 weeks\u2019 GA in all neonatal intensive care units in Canada with follow-up in the neonatal follow-up clinics. Short-term morbidities, neurodevelopmental impairment, significant neurodevelopmental impairment, and resource utilization of infants born at \u2264 24 weeks were compared with neonates born at 25 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 803 neonates discharged alive, 636 (80.4%) infants born at \u2264 25 weeks\u2019 GA were assessed at 18 to 24 months. Caesarean delivery, lower birth weight, and less antenatal steroid exposure were more common in infants born \u2264 24 weeks as compared with 25 weeks. They had significantly higher incidences of ductus arteriosus ligation, severe intracranial hemorrhage, retinopathy of prematurity as well as longer length of stay, central line days, days on respiratory support, days on total parenteral nutrition, days on antibiotics, and need for postnatal steroids. Neurodevelopmental impairment rates were 68.9, 64.5, and 55.6% (P=0.01) and significant neurodevelopmental impairment rates were 39.3, 29.6, and 20.9% (P&amp;lt;0.01) for infants \u2264 23, 24, and 25 weeks GA, respectively. Postdischarge service referrals were higher for those \u2264 23 weeks. Nonsurviving infants born at 25 weeks GA had higher resource utilization during admission than infants born less than 25 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Adverse outcomes and resource usage were significantly higher among infants born \u2264 24 weeks GA as compared with 25 weeks GA.<\/jats:p><\/jats:sec>","DOI":"10.1093\/pch\/pxz002","type":"journal-article","created":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T18:29:39Z","timestamp":1549564179000},"page":"207-215","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes and resource usage of infants born at \u2264 25 weeks gestation in Canada"],"prefix":"10.1093","volume":"25","author":[{"given":"Amy","family":"Shafey","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Toronto, Toronto, Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rani 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