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It results from a variety of heritable and acquired causes and is linked to multiple deleterious effects on a child's development that can be ameliorated by prompt identification and individualized therapies. Diagnosing hearing loss in newborns is challenging, especially in mild or progressive cases, and its management requires a multidisciplinary team of healthcare providers comprising audiologists, pediatricians, otolaryngologists, and genetic counselors. While physiologic newborn hearing screening has resulted in earlier diagnosis of hearing loss than ever before, a growing body of knowledge supports the concurrent implementation of genetic and cytomegalovirus testing to offset the limitations inherent to a singular screening modality. In this review, we discuss the contemporary role of screening for hearing loss in newborns as well as future directions in its diagnosis and treatment.<\/jats:p>","DOI":"10.1093\/pcmedi\/pbaa025","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T16:57:27Z","timestamp":1594918647000},"page":"175-186","source":"Crossref","is-referenced-by-count":29,"title":["Future directions for screening and treatment in congenital hearing loss"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8046-407X","authenticated-orcid":false,"given":"Ryan K","family":"Thorpe","sequence":"first","affiliation":[{"name":"Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, 375 Newton Rd, Iowa City, IA 52242, USA"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J H","family":"Smith","sequence":"additional","affiliation":[{"name":"Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, 375 Newton Rd, Iowa City, IA 52242, USA"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA"},{"name":"The Interdisciplinary Graduate Program in Genetics, University of Iowa, 375 Newton Rd, Iowa City, IA 52242, USA"},{"name":"Iowa Institute of Human Genetics, University of Iowa, 375 Newton Rd, Iowa City, IA 52242, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"2022032115005574400_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1749-6632.1991.tb19572.x","article-title":"Genetic epidemiology of hearing 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