{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T07:18:18Z","timestamp":1784013498273,"version":"3.55.0"},"reference-count":78,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"MEXT KAKENHI","award":["JP18H05484"],"award-info":[{"award-number":["JP18H05484"]}]},{"name":"MEXT KAKENHI","award":["JP18H05489"],"award-info":[{"award-number":["JP18H05489"]}]},{"name":"MEXT KAKENHI","award":["JP20H05405"],"award-info":[{"award-number":["JP20H05405"]}]},{"name":"MEXT KAKENHI","award":["JP21H05652"],"award-info":[{"award-number":["JP21H05652"]}]},{"name":"MEXT KAKENHI","award":["JP23H04191"],"award-info":[{"award-number":["JP23H04191"]}]},{"DOI":"10.13039\/501100000646","name":"JSPS","doi-asserted-by":"publisher","award":["JP20H03271"],"award-info":[{"award-number":["JP20H03271"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000646","name":"JSPS","doi-asserted-by":"publisher","award":["JP23K27189"],"award-info":[{"award-number":["JP23K27189"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000646","name":"JSPS","doi-asserted-by":"publisher","award":["JP18H02466"],"award-info":[{"award-number":["JP18H02466"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000646","name":"JSPS","doi-asserted-by":"publisher","award":["JP23K23912"],"award-info":[{"award-number":["JP23K23912"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"name":"ERATO JST","award":["JPMJER1602"],"award-info":[{"award-number":["JPMJER1602"]}]},{"DOI":"10.13039\/100007684","name":"Asahi Glass Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007684","id-type":"DOI","asserted-by":"publisher"}]},{"name":"G-7 Scholarship Foundation"},{"DOI":"10.13039\/100005286","name":"Canon Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005286","id-type":"DOI","asserted-by":"publisher"}]},{"name":"World-leading Innovative Graduate Study Program in Proactive Environmental Studies"},{"DOI":"10.13039\/501100004721","name":"The University of Tokyo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004721","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In vascular plants, xylem vessels transport water and contribute to structural integrity. As part of vessel formation, xylem cells deposit secondary cell walls (SCWs), which are composed of cellulose, hemicellulose, and lignin polymers. Under environmental challenges such as pathogen attack, a growth\u2013defense trade-off limits xylem vessel development. Understanding the mechanism regulating this trade-off has implications for understanding of plant strategy to utilize their carbon resources because SCWs contain large amounts of densely packed high-carbon compounds. Here, we investigated the effect of pathogen responses induced by the peptide defense elicitor flagellin22 (flg22) on VASCULAR-RELATED NAC-DOMAIN7 (VND7)\u2013dependent xylem vessel formation in Arabidopsis (Arabidopsis thaliana). Treatment with flg22 decreased xylem transport and delayed ectopic xylem vessel differentiation, including SCW deposition, in plants with a dexamethasone-inducible VND7 system, suggesting that the plant prioritized defense responses over xylem formation. Consistent with this, transcriptome analysis revealed that flg22 treatment suppressed SCW-related genes and activated immune-related genes. Salicylic acid (SA) treatment had a similar inhibitory effect on VND7-dependent xylem vessel formation, and the sid2\u20132 and npr1\u20131 mutants, which are defective in SA biosynthesis and signaling, respectively, did not exhibit flg22-induced inhibition of xylem transport activity; these highlight the role of SA, which is biosynthesized from phenylalanine during immune responses, as a key mediator of the competition between xylem vessel formation and immune responses. These findings provide insights into how plants flexibly regulate xylem development under biotic stress to optimize their development.<\/jats:p>","DOI":"10.1093\/pcp\/pcaf086","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T11:59:18Z","timestamp":1753444758000},"page":"1360-1374","source":"Crossref","is-referenced-by-count":3,"title":["Salicylic acid\u2013mediated competitive regulation of xylem vessel formation and defense responses in <i>Arabidopsis thaliana<\/i>"],"prefix":"10.1093","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8065-7373","authenticated-orcid":false,"given":"Ya","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo , 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo , 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaokun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo , 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5847-6620","authenticated-orcid":false,"given":"Ryosuke","family":"Sano","sequence":"additional","affiliation":[{"name":"Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology , 8916-5 Takayama-cho, Ikoma, Nara 630-0192 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-4738","authenticated-orcid":false,"given":"Taku","family":"Demura","sequence":"additional","affiliation":[{"name":"Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology , 8916-5 Takayama-cho, Ikoma, Nara 630-0192 ,","place":["Japan"]},{"name":"RIKEN Center for Sustainable Resource Science , 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5429-3310","authenticated-orcid":false,"given":"Misato","family":"Ohtani","sequence":"additional","affiliation":[{"name":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo , 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562 ,","place":["Japan"]},{"name":"Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology , 8916-5 Takayama-cho, Ikoma, Nara 630-0192 ,","place":["Japan"]},{"name":"RIKEN Center for Sustainable Resource Science , 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"2025092509064142600_ref2","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1093\/treephys\/tpz106","article-title":"Involvement of VNS NAC-domain transcription factors in tracheid formation in Pinus taeda","volume":"40","author":"Akiyoshi","year":"2020","journal-title":"Tree Physiol."},{"key":"2025092509064142600_ref3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1365-313X.2008.03592.x","article-title":"Cysteine proteases XCP1 and XCP2 aid micro-autolysis within the intact central vacuole during xylogenesis in Arabidopsis roots","volume":"56","author":"Avci","year":"2008","journal-title":"Plant J."},{"key":"2025092509064142600_ref4","doi-asserted-by":"crossref","first-page":"6487","DOI":"10.1093\/jxb\/eru366","article-title":"Expression patterns of FLAGELLIN SENSING 2 map to bacterial entry sites in plant shoots and roots","volume":"65","author":"Beck","year":"2014","journal-title":"J. Exp. Bot."},{"key":"2025092509064142600_ref5","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11103-009-9458-1","article-title":"Early genomic responses to salicylic acid in Arabidopsis","volume":"70","author":"Blanco","year":"2009","journal-title":"Plant Mol. Biol."},{"key":"2025092509064142600_ref6","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev.arplant.57.032905.105346","article-title":"A renaissance of elicitors: perception of microbe-associated molecular patterns and danger signals by pattern-recognition receptors","volume":"60","author":"Boller","year":"2009","journal-title":"Annu. Rev. Plant Biol."},{"key":"2025092509064142600_ref7","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1105\/tpc.105.031542","article-title":"Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics","volume":"17","author":"Brown","year":"2005","journal-title":"Plant Cell"},{"key":"2025092509064142600_ref8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0092-8674(00)81858-9","article-title":"The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats","volume":"10","author":"Cao","year":"1997","journal-title":"Cell."},{"key":"2025092509064142600_ref9","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1111\/bph.13828","article-title":"Reactive oxygen species: key regulators in vascular health and diseases","volume":"175","author":"Chen","year":"2018","journal-title":"Br. J. Pharmacol."},{"key":"2025092509064142600_ref10","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.1038\/s41467-023-40406-7","article-title":"XCP1 cleaves Pathogenesis-related protein 1 into CAPE9 for systemic immunity in Arabidopsis","volume":"14","author":"Chen","year":"2023","journal-title":"Nat. Commun."},{"key":"2025092509064142600_ref11","doi-asserted-by":"publisher","DOI":"10.1101\/2025.02.06.636724","article-title":"The proteomics landscape of pattern triggered immunity in the Arabidopsis leaf apoplast","volume-title":"bioRxiv","author":"Chen","year":"2025"},{"key":"2025092509064142600_ref12","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/jxb\/erh179","article-title":"Elemental Sulphur as an induced antifungal substance in plant defence","volume":"55","author":"Cooper","year":"2004","journal-title":"J. Exp. Bot."},{"key":"2025092509064142600_ref14","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/mp\/ssn019","article-title":"Activation of defense response pathways by OGs and flg22 elicitors in Arabidopsis seedlings","volume":"1","author":"Denoux","year":"2008","journal-title":"Mol. Plant"},{"key":"2025092509064142600_ref15","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.cell.2018.03.044","article-title":"Opposite roles of salicylic acid receptors NPR1 and NPR3\/NPR4 in transcriptional regulation of plant immunity","volume":"173","author":"Ding","year":"2018","journal-title":"Cell"},{"key":"2025092509064142600_ref16","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1046\/j.1364-3703.2002.00131.x","article-title":"The phenylpropanoid pathway and plant defence\u2014a genomis perspective","volume":"3","author":"Dixon","year":"2002","journal-title":"Mol. Plant Pathol."},{"key":"2025092509064142600_ref17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/nph.15540","article-title":"Cargo-dependent and cell wall-associated xylem transport in Arabidopsis","volume":"222","author":"Endo","year":"2019","journal-title":"New Phytol."},{"key":"2025092509064142600_ref18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1046\/j.1365-313X.1999.00265.x","article-title":"Plants have a sensitive perception system for the most conserved domain of bacterial flagellin","volume":"18","author":"Felix","year":"1999","journal-title":"Plant J."},{"key":"2025092509064142600_ref19","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1364-3703.2006.00323.x","article-title":"Physiology and molecular aspects of verticillium wilt diseases caused by V. Dahliae and V. Albo-atrum","volume":"7","author":"Fradin","year":"2006","journal-title":"Mol. Plant Pathol."},{"key":"2025092509064142600_ref20","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1104\/pp.010514","article-title":"The Arabidopsis xylem peptidase XCP1 is a tracheary element Vacuolar protein that may Be a papain ortholog","volume":"128","author":"Funk","year":"2002","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref21","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/pcp\/pcae037","article-title":"Multiple roles of Brassinosteroid signaling in vascular development","volume":"65","author":"Furuya","year":"2024","journal-title":"Plant Cell Physiol"},{"key":"2025092509064142600_ref22","doi-asserted-by":"crossref","first-page":"20814","DOI":"10.1073\/pnas.1117873108","article-title":"Salicylic acid mediates the reduced growth of lignin down-regulated plants","volume":"108","author":"Gallego-Giraldo","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2025092509064142600_ref24","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1186\/1471-2229-10-232","article-title":"The Ve-mediated resistance response of the tomato to verticillium dahliae involves H2O2, peroxidase and lignins and drives PALgene expression","volume":"10","author":"Gayoso","year":"2010","journal-title":"BMC Plant Biol."},{"key":"2025092509064142600_ref25","doi-asserted-by":"crossref","first-page":"8245","DOI":"10.1073\/pnas.0305876101","article-title":"Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis","volume":"101","author":"Glawischnig","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2025092509064142600_ref26","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1093\/treephys\/tpz144","article-title":"Distinct xylem responses to acute vs prolonged drought in pine trees","volume":"40","author":"Gu\u00e9rin","year":"2020","journal-title":"Tree Physiol."},{"key":"2025092509064142600_ref28","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1093\/pcp\/pcad096","article-title":"Inhibition of NPR1 leads to shoot growth improvement under low-calcium conditions in Arabidopsis","volume":"64","author":"Hashimoto","year":"2023","journal-title":"Plant Cell Physiol"},{"key":"2025092509064142600_ref29","doi-asserted-by":"publisher","DOI":"10.1101\/742742","article-title":"Transcriptional dynamics of the salicylic acid response and its interplay with the Jasmonic acid pathway","author":"Hickman","year":"2019"},{"key":"2025092509064142600_ref30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3390\/plants9010039","article-title":"The progression of xylem vessel cell differentiation is dependent on the activity level of VND7 in Arabidopsis thaliana","volume":"9","author":"Hirai","year":"2019","journal-title":"Plants"},{"key":"2025092509064142600_ref31","doi-asserted-by":"crossref","first-page":"111686","DOI":"10.1016\/j.plantsci.2023.111686","article-title":"Conservation and divergence of flg22, pep1 and nlp20 in activation of immune response and inhibition of root development","volume":"331","author":"Huang","year":"2023","journal-title":"Plant Sci."},{"key":"2025092509064142600_ref33","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1094\/MPMI-18-0891","article-title":"Bacterial type two secretion system secreted proteins: double-edged swords for plant pathogens","volume":"18","author":"Jha","year":"2005","journal-title":"Mol. Plant-Microbe Interactions\u00ae"},{"key":"2025092509064142600_ref35","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/ppl.12766","article-title":"The plant hormone auxin directs timing of xylem development by inhibition of secondary cell wall deposition through repression of secondary wall NAC-domain transcription factors","volume":"165","author":"Johnsson","year":"2019","journal-title":"Physiol. Plant."},{"key":"2025092509064142600_ref36","doi-asserted-by":"crossref","first-page":"102135","DOI":"10.1016\/j.pbi.2021.102135","article-title":"Xylem vessel cell differentiation: a best model for new integrative cell biology?","volume":"64","author":"Kamon","year":"2021","journal-title":"Curr. Opin. Plant Biol."},{"key":"2025092509064142600_ref37","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1104\/pp.114.250985","article-title":"The Arabidopsis transcription factor BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 is a direct substrate of MITOGEN-ACTIVATED PROTEIN KINASE6 and regulates immunity","volume":"167","author":"Kang","year":"2015","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref38","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1111\/nph.16915","article-title":"Salicylic acid regulates PIN2 auxin transporter hyperclustering and root gravitropic growth via Remorin-dependent lipid nanodomain organisation in Arabidopsis thaliana","volume":"229","author":"Ke","year":"2021","journal-title":"New Phytol."},{"key":"2025092509064142600_ref39","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1093\/aob\/mcu126","article-title":"The MYB46\/MYB83-mediated transcriptional regulatory programme is a gatekeeper of secondary wall biosynthesis","volume":"114","author":"Ko","year":"2014","journal-title":"Annal Bot"},{"key":"2025092509064142600_ref40","doi-asserted-by":"crossref","first-page":"3504","DOI":"10.1038\/ncomms4504","article-title":"Plant GSK3 proteins regulate xylem cell differentiation downstream of TDIF\u2013TDR signalling","volume":"5","author":"Kondo","year":"2014","journal-title":"Nat. Commun."},{"key":"2025092509064142600_ref41","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3389\/fpls.2014.00315","article-title":"Regulation of xylem cell fate","volume":"5","author":"Kondo","year":"2014","journal-title":"Front. Plant Sci."},{"key":"2025092509064142600_ref42","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1101\/gad.1331305","article-title":"Transcription switches for protoxylem and metaxylem vessel formation","volume":"19","author":"Kubo","year":"2005","journal-title":"Genes Dev."},{"key":"2025092509064142600_ref43","doi-asserted-by":"crossref","first-page":"8625","DOI":"10.1038\/srep08625","article-title":"Proteomic identification of early salicylate- and flg22-responsive redox-sensitive proteins in Arabidopsis","volume":"5","author":"Liu","year":"2015","journal-title":"Sci. Rep."},{"key":"2025092509064142600_ref44","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/plcell\/koad262","article-title":"XYLEM CYSTEINE PEPTIDASE 1 and its inhibitor CYSTATIN 6 regulate pattern-triggered immunity by modulating the stability of the NADPH oxidase RESPIRATORY BURST OXIDASE HOMOLOG D","volume":"36","author":"Liu","year":"2024","journal-title":"Plant Cell"},{"key":"2025092509064142600_ref45","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/jipb.12041","article-title":"The plant vascular system: evolution, development and functions","volume":"55","author":"Lucas","year":"2013","journal-title":"J Integ Plant Biol"},{"key":"2025092509064142600_ref46","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1094\/MPMI-07-10-0149","article-title":"Callose deposition: a multifaceted plant defense response","volume":"24","author":"Luna","year":"2011","journal-title":"Mol. Plant-Microbe Interact."},{"key":"2025092509064142600_ref47","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/aob\/mcy005","article-title":"The cell biology of secondary cell wall biosynthesis","volume":"121","author":"Meents","year":"2018","journal-title":"Annal Bot"},{"key":"2025092509064142600_ref48","doi-asserted-by":"crossref","first-page":"288","DOI":"10.3389\/fpls.2015.00288","article-title":"NAC-MYB-based transcriptional regulation of secondary cell wall biosynthesis in land plants","volume":"6","author":"Nakano","year":"2015","journal-title":"Front. Plant Sci."},{"key":"2025092509064142600_ref49","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/tpj.12018","article-title":"MYB103 is required for FERULATE-5-HYDROXYLASE expression and syringyl lignin biosynthesis in Arabidopsis stems","volume":"73","author":"\u00d6hman","year":"2013","journal-title":"Plant J."},{"key":"2025092509064142600_ref50","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.copbio.2018.10.002","article-title":"The quest for transcriptional hubs of lignin biosynthesis: beyond the NAC-MYB-gene regulatory network model","volume":"56","author":"Ohtani","year":"2019","journal-title":"Current Opin Biotechnol"},{"key":"2025092509064142600_ref51","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1365-313X.2011.04614.x","article-title":"A NAC domain protein family contributing to the regulation of wood formation in poplar","volume":"67","author":"Ohtani","year":"2011","journal-title":"Plant J."},{"key":"2025092509064142600_ref52","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1104\/pp.16.01230","article-title":"Primary metabolism during biosynthesis of secondary wall polymers of protoxylem vessel elements","volume":"172","author":"Ohtani","year":"2016","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref53","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1104\/pp.19.00130","article-title":"Salicylic acid affects root meristem patterning via auxin distribution in a concentration-dependent manner","volume":"180","author":"Pasternak","year":"2019","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref54","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1146\/annurev-arplant-081320-092855","article-title":"Salicylic acid: biosynthesis and signaling","volume":"72","author":"Peng","year":"2021","journal-title":"Annu. Rev. Plant Biol."},{"key":"2025092509064142600_ref55","doi-asserted-by":"crossref","first-page":"3298","DOI":"10.1093\/plcell\/koae221","article-title":"Active protein ubiquitination regulates xylem vessel functionality","volume":"36","author":"Phookaew","year":"2024","journal-title":"Plant Cell"},{"key":"2025092509064142600_ref84a","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S0005-2728(89)80347-0","article-title":"Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy","volume":"975","author":"Porra","year":"1989","journal-title":"Biochim. Biophys. Acta."},{"key":"2025092509064142600_ref56","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1439-0434.1999.tb03819.x","article-title":"Histopathology of susceptible and resistant Capsicum annuum cultivars infected with Ralstonia solanacearum","volume":"147","author":"Rahman","year":"1999","journal-title":"J. Phytopathol."},{"key":"2025092509064142600_ref57","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3389\/fpls.2020.00570","article-title":"Coping with water limitation: hormones that modify plant root xylem development","volume":"11","author":"Ramachandran","year":"2020","journal-title":"Front. Plant Sci."},{"key":"2025092509064142600_ref58","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1016\/j.cub.2021.04.057","article-title":"Abscisic acid signaling activates distinct VND transcription factors to promote xylem differentiation in Arabidopsis","volume":"31","author":"Ramachandran","year":"2021","journal-title":"Curr. Biol."},{"key":"2025092509064142600_ref59","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1104\/pp.108.130070","article-title":"Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis","volume":"149","author":"Rippert","year":"2009","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref60","doi-asserted-by":"crossref","first-page":"e0297124","DOI":"10.1371\/journal.pone.0297124","article-title":"Comparative RNA-seq analysis of Arabidopsis thaliana response to AtPep1 and flg22, reveals the identification of PP2-B13 and ACLP1 as new members in pattern-triggered immunity","volume":"19","author":"Safaeizadeh","year":"2024","journal-title":"PLoS One"},{"key":"2025092509064142600_ref61","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1139\/b06-065","article-title":"The cell biology of wood formation: from cambial divisions to mature secondary xylem","volume":"84","author":"Samuels","year":"2006","journal-title":"Can. J. Bot."},{"key":"2025092509064142600_ref62","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.sjbs.2019.06.002","article-title":"Fusarium oxysporum f. sp. lycopersici causal agent of vascular wilt disease of tomato: biology to diversity\u2013 a review","volume":"26","author":"Srinivas","year":"2019","journal-title":"Saudi J. Biol. Sci."},{"key":"2025092509064142600_ref63","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-3059.2004.01101.x","article-title":"Type-II secretion pathway structural gene xpsE, xylanase- and cellulase secretion and virulence in Xanthomonas oryzae pv. Oryzae","volume":"54","author":"Sun","year":"2005","journal-title":"Plant Pathol."},{"key":"2025092509064142600_ref64","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.1038\/s41467-018-06430-8","article-title":"Natural variation at XND1 impacts root hydraulics and trade-off for stress responses in Arabidopsis","volume":"9","author":"Tang","year":"2018","journal-title":"Nat. Commun."},{"key":"2025092509064142600_ref65","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s11103-007-9142-2","article-title":"Identification of cellulose synthase AtCesA7 (IRX3) in vivo phosphorylation sites\u2014a potential role in regulating protein degradation","volume":"64","author":"Taylor","year":"2007","journal-title":"Plant Mol. Biol."},{"key":"2025092509064142600_ref66","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1073\/pnas.0337628100","article-title":"Interactions among three distinct CesA proteins essential for cellulose synthesis","volume":"100","author":"Taylor","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2025092509064142600_ref67","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/nph.13286","article-title":"Transcriptional networks in plant immunity","volume":"206","author":"Tsuda","year":"2015","journal-title":"New Phytol."},{"key":"2025092509064142600_ref68","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1093\/pcp\/pcad130","article-title":"The carbon flow shifts from primary to secondary metabolism during xylem vessel cell differentiation in Arabidopsis thaliana","volume":"64","author":"Uy","year":"2023","journal-title":"Plant Cell Physiol"},{"key":"2025092509064142600_ref69","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev.phyto.44.070505.143425","article-title":"Significance of inducible Defense-related proteins in infected plants","volume":"44","author":"Van Loon","year":"2006","journal-title":"Annu. Rev. Phytopathol."},{"key":"2025092509064142600_ref71","doi-asserted-by":"crossref","first-page":"580753","DOI":"10.3389\/fpls.2020.580753","article-title":"Phenolic compound induction in plant-microbe and plant-insect interactions: a meta-analysis","volume":"11","author":"Wallis","year":"2020","journal-title":"Front. Plant Sci."},{"key":"2025092509064142600_ref72","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/j.cub.2007.09.025","article-title":"Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway","volume":"17","author":"Wang","year":"2007","journal-title":"Curr. Biol."},{"key":"2025092509064142600_ref73","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/35107108","article-title":"Isochorismate synthase is required to synthesize salicylic acid for plant defence","volume":"29","author":"Wildermuth","year":"2001","journal-title":"Nature."},{"key":"2025092509064142600_ref74","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1104\/pp.010687","article-title":"Elemental Sulfur and thiol accumulation in tomato and Defense against a fungal vascular pathogen","volume":"128","author":"Williams","year":"2002","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref75","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1093\/plcell\/koab073","article-title":"Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species","volume":"33","author":"Winkelm\u00fcller","year":"2021","journal-title":"Plant Cell"},{"key":"2025092509064142600_ref76","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1128\/JB.00978-07","article-title":"AvrACXcc8004, a type III effector with a leucine-rich repeat domain from Xanthomonas campestris pathovar campestris confers Avirulence in vascular tissues of Arabidopsis thaliana ecotype Col-0","volume":"190","author":"Xu","year":"2008","journal-title":"J. Bacteriol."},{"key":"2025092509064142600_ref77","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1365-313X.2008.03533.x","article-title":"VASCULAR-RELATED NAC-DOMAIN7 is involved in the differentiation of all types of xylem vessels in Arabidopsis roots and shoots","volume":"55","author":"Yamaguchi","year":"2008","journal-title":"Plant J."},{"key":"2025092509064142600_ref78","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1104\/pp.110.154013","article-title":"VASCULAR-RELATED NAC-DOMAIN6 and VASCULAR-RELATED NAC-DOMAIN7 effectively induce transdifferentiation into xylem vessel elements under control of an induction system","volume":"153","author":"Yamaguchi","year":"2010","journal-title":"Plant Physiol."},{"key":"2025092509064142600_ref79","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1365-313X.2011.04514.x","article-title":"VASCULAR-RELATED NAC-DOMAIN 7 directly regulates the expression of a broad range of genes for xylem vessel formation: direct target genes of VND7","volume":"66","author":"Yamaguchi","year":"2011","journal-title":"Plant J."},{"key":"2025092509064142600_ref80","doi-asserted-by":"crossref","first-page":"704697","DOI":"10.3389\/fpls.2021.704697","article-title":"Phylogenetic occurrence of the phenylpropanoid pathway and lignin biosynthesis in plants","volume":"12","author":"Yao","year":"2021","journal-title":"Front. Plant Sci."},{"key":"2025092509064142600_ref81","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.molp.2022.10.001","article-title":"Salicylic acid inhibits gibberellin signaling through receptor interactions","volume":"15","author":"Yu","year":"2022","journal-title":"Mol. Plant"},{"key":"2025092509064142600_ref82","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/pcp\/pcr185","article-title":"MYB46 and MYB83 bind to the SMRE sites and directly activate a suite of transcription factors and secondary wall biosynthetic genes","volume":"53","author":"Zhong","year":"2012","journal-title":"Plant Cell Physiol"},{"key":"2025092509064142600_ref83","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1105\/tpc.108.063321","article-title":"MYB58 and MYB63 are transcriptional activators of the lignin biosynthetic pathway during secondary cell wall formation in Arabidopsis","volume":"21","author":"Zhou","year":"2009","journal-title":"Plant Cell"},{"key":"2025092509064142600_ref84","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/nature02485","article-title":"Bacterial disease resistance in Arabidopsis through flagellin perception","volume":"428","author":"Zipfel","year":"2004","journal-title":"Nature"}],"container-title":["Plant and Cell Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pcp\/advance-article-pdf\/doi\/10.1093\/pcp\/pcaf086\/63845101\/pcaf086.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pcp\/article-pdf\/66\/9\/1360\/63845101\/pcaf086.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pcp\/article-pdf\/66\/9\/1360\/63845101\/pcaf086.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T13:07:00Z","timestamp":1758805620000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pcp\/article\/66\/9\/1360\/8212270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":78,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,7,25]]},"published-print":{"date-parts":[[2025,9,25]]}},"URL":"https:\/\/doi.org\/10.1093\/pcp\/pcaf086","relation":{},"ISSN":["0032-0781","1471-9053"],"issn-type":[{"value":"0032-0781","type":"print"},{"value":"1471-9053","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,7,25]]}}}