{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:55:55Z","timestamp":1791276955496,"version":"4.1.0"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Agriculture Science and Technology Major Project"},{"name":"Innovation Program of Chinese Academy of Agricultural Sciences","award":["Y2026YC02"],"award-info":[{"award-number":["Y2026YC02"]}],"id":[{"id":"https:\/\/ror.org\/0313jb750","id-type":"ROR","asserted-by":"crossref"}]},{"name":"State Key Laboratory of Crop Gene Resources and Breeding","award":["S2026QZ13"],"award-info":[{"award-number":["S2026QZ13"]}]},{"name":"Inner Mongolia Innovation Center of Biological Breeding Technology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Appropriate heading date is an important safeguard for stabilizing rice yield and quality. Heading integrator Ehd1 and florigen Hd3a are crucial for rice heading. However, the mechanism by which Ehd1 transmits heading signals to Hd3a and the accurate regulation of Hd3a expression remains unclear. Here, we found that OsWOX13 functions as a signal transducer from Ehd1 to Hd3a for the accurate regulation of rice heading date. Ehd1 can directly bind to the OsWOX13 promoter, OsWOX13, in turn, binds to the Hd3a promoter to activate its expression. OsWOX13 interacts with Hd3a to inhibit OsWOX13-mediated activation of Hd3a expression, which precisely controls Hd3a levels. Meanwhile, late-heading phenotypes were observed in the ehd1, Oswox13, Oswox13 ehd1, hd3a, and Oswox13 hd3a, demonstrating that Ehd1, OsWOX13, and Hd3a coordinately regulate rice heading date. Furthermore, OsWOX13 can be divided into 2 haplotypes, Hap-T and Hap-C. Ehd1 elevated OsWOX13 expression in Hap-T compared with Hap-C. Longjing 31T-C (carrying Hap-C) exhibited later heading dates than Longjing 31 (carrying Hap-T). Rice varieties carrying Hap-T are predominantly cultivated in high-latitude regions. This study provides genetic resources and a theoretical foundation for improving the regional and climatic adaptability of rice.<\/jats:p>","DOI":"10.1093\/plcell\/koag246","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:31:49Z","timestamp":1786991509000},"source":"Crossref","is-referenced-by-count":1,"title":["OsWOX13 functions as a heading signal transducer from integrator Ehd1 to florigen for the accurate regulation of rice heading date"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9959-2621","authenticated-orcid":false,"given":"Ming","family":"Yu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minrui","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3988-6534","authenticated-orcid":false,"given":"Xudong","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9017-9045","authenticated-orcid":false,"given":"Xinyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maohong","family":"Cai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6461-0264","authenticated-orcid":false,"given":"Liang","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2594-3198","authenticated-orcid":false,"given":"Shirong","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0384-573X","authenticated-orcid":false,"given":"Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3847-8061","authenticated-orcid":false,"given":"Chao","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5054-0685","authenticated-orcid":false,"given":"Yimin","family":"Ling","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7614-3451","authenticated-orcid":false,"given":"Minxi","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0024-2127","authenticated-orcid":false,"given":"Limin","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9649-7905","authenticated-orcid":false,"given":"Dekun","family":"Lei","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6197-4234","authenticated-orcid":false,"given":"Bingke","family":"Luo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6684-5703","authenticated-orcid":false,"given":"Qiyu","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4886-5973","authenticated-orcid":false,"given":"Wen","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8567-6013","authenticated-orcid":false,"given":"Xin","family":"Jin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5584-1956","authenticated-orcid":false,"given":"Lizhuo","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-3529","authenticated-orcid":false,"given":"Yulong","family":"Ren","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0994-6922","authenticated-orcid":false,"given":"Zhichao","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3979-1810","authenticated-orcid":false,"given":"Jie","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8473-1948","authenticated-orcid":false,"given":"Cailin","family":"Lei","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4234-9927","authenticated-orcid":false,"given":"Zhijun","family":"Cheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-286X","authenticated-orcid":false,"given":"Qibing","family":"Lin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4936-7562","authenticated-orcid":false,"given":"Xiuping","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1142-3562","authenticated-orcid":false,"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4039-3350","authenticated-orcid":false,"given":"Shanshan","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0017-8760","authenticated-orcid":false,"given":"Jianmin","family":"Wan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences , Beijing 100081 ,","place":["China"]},{"name":"State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"2026100604470474800_koag246-B1","doi-asserted-by":"publisher","first-page":"4752","DOI":"10.1093\/plcell\/koae248","article-title":"The strigolactone receptor DWARF14 regulates flowering time in Arabidopsis","volume":"36","author":"Bai","year":"2024","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B2","doi-asserted-by":"publisher","first-page":"2801","DOI":"10.1105\/tpc.17.00645","article-title":"Antagonistic transcription factor complexes modulate the floral transition in rice","volume":"29","author":"Brambilla","year":"2017","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B3","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1111\/jipb.12033","article-title":"Molecular control of flowering in response to day length in rice","volume":"55","author":"Brambilla","year":"2013","journal-title":"J Integr Plant Biol"},{"key":"2026100604470474800_koag246-B4","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.molp.2020.11.013","article-title":"DHD4, a CONSTANS-like family transcription factor, delays heading date by affecting the formation of the FAC complex in rice","volume":"14","author":"Cai","year":"2021","journal-title":"Mol Plant"},{"key":"2026100604470474800_koag246-B5","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1111\/pbi.13462","article-title":"OsRE1 interacts with OsRIP1 to regulate rice heading date by finely modulating Ehd1 expression","volume":"19","author":"Chai","year":"2021","journal-title":"Plant Biotechnol J"},{"key":"2026100604470474800_koag246-B6","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s12870-018-1330-5","article-title":"Natural variation at qHd1 affects heading date acceleration at high temperatures with pleiotropism for yield traits in rice","volume":"18","author":"Chen","year":"2018","journal-title":"BMC Plant Biol"},{"key":"2026100604470474800_koag246-B7","doi-asserted-by":"publisher","first-page":"864","DOI":"10.3389\/fpls.2020.00864","article-title":"A combination of long-day suppressor genes contributes to the northward expansion of rice","volume":"11","author":"Cui","year":"2020","journal-title":"Front Plant Sci"},{"key":"2026100604470474800_koag246-B8","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1186\/1471-2148-8-291","article-title":"Genes of the most conserved WOX clade in plants affect root and flower development in Arabidopsis","volume":"8","author":"Deveaux","year":"2008","journal-title":"BMC Evol Biol"},{"key":"2026100604470474800_koag246-B9","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1101\/gad.1189604","article-title":"Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1","volume":"18","author":"Doi","year":"2004","journal-title":"Genes Dev"},{"key":"2026100604470474800_koag246-B10","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1105\/tpc.19.00023","article-title":"OsSHI1 regulates plant architecture through modulating the transcriptional activity of IPA1 in rice","volume":"31","author":"Duan","year":"2019","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B11","doi-asserted-by":"publisher","first-page":"e1003281","DOI":"10.1371\/journal.pgen.1003281","article-title":"Ehd4 encodes a novel and Oryza-genus-specific regulator of photoperiodic flowering in rice","volume":"9","author":"Gao","year":"2013","journal-title":"PLoS Genet"},{"key":"2026100604470474800_koag246-B12","doi-asserted-by":"publisher","first-page":"16337","DOI":"10.1073\/pnas.1418204111","article-title":"Days to heading 7, a major quantitative locus determining photoperiod sensitivity and regional adaptation in rice","volume":"111","author":"Gao","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026100604470474800_koag246-B13","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1093\/plcell\/koad318","article-title":"Transcription factors WOX11 and LBD16 function with histone demethylase JMJ706 to control crown root development in rice","volume":"36","author":"Geng","year":"2024","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B14","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1038\/s41586-025-08883-6","article-title":"A pangenome reference of wild and cultivated rice","volume":"642","author":"Guo","year":"2025","journal-title":"Nature"},{"key":"2026100604470474800_koag246-B15","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1139\/gen-2020-0029","article-title":"Genome-wide identification and characterization of WOX genes in Cucumis sativus","volume":"64","author":"Han","year":"2021","journal-title":"Genome"},{"key":"2026100604470474800_koag246-B16","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00122-023-04391-1","article-title":"Adaptation to high latitudes through a novel allele of Hd3a strongly promoting heading date in rice","volume":"136","author":"Han","year":"2023","journal-title":"Theor Appl Genet"},{"key":"2026100604470474800_koag246-B17","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1111\/tpj.12268","article-title":"Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response","volume":"76","author":"Hori","year":"2013","journal-title":"Plant J"},{"key":"2026100604470474800_koag246-B18","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1038\/ng.1018","article-title":"Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm","volume":"44","author":"Huang","year":"2011","journal-title":"Nat Genet"},{"key":"2026100604470474800_koag246-B19","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/nature19760","article-title":"Genomic architecture of heterosis for yield traits in rice","volume":"537","author":"Huang","year":"2016","journal-title":"Nature"},{"key":"2026100604470474800_koag246-B20","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1038\/ng.606","article-title":"A pair of floral regulators sets critical day length for Hd3a florigen expression in rice","volume":"42","author":"Itoh","year":"2010","journal-title":"Nat Genet"},{"key":"2026100604470474800_koag246-B21","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.tplants.2009.07.005","article-title":"Flowering time control and applications in plant breeding","volume":"14","author":"Jung","year":"2009","journal-title":"Trends Plant Sci"},{"key":"2026100604470474800_koag246-B22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2101846119","article-title":"WUSCHEL-related homeobox family genes in rice control lateral root primordium size","volume":"119","author":"Kawai","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026100604470474800_koag246-B23","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1104\/pp.107.103291","article-title":"OsMADS51 is a short-day flowering promoter that functions upstream of Ehd1, OsMADS14, and Hd3a","volume":"145","author":"Kim","year":"2007","journal-title":"Plant Physiol"},{"key":"2026100604470474800_koag246-B24","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1093\/bbb\/zbae115","article-title":"Knockout of OsWOX13 moderately delays flowering in rice under natural long-day conditions","volume":"88","author":"Kim","year":"2024","journal-title":"Biosci Biotechnol Biochem"},{"key":"2026100604470474800_koag246-B25","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1242\/dev.008631","article-title":"Hd3a and RFT1 are essential for flowering in rice","volume":"135","author":"Komiya","year":"2008","journal-title":"Development"},{"key":"2026100604470474800_koag246-B26","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1111\/j.1365-313X.2010.04226.x","article-title":"OsCOL4 is a constitutive flowering repressor upstream of Ehd1 and downstream of OsphyB","volume":"63","author":"Lee","year":"2010","journal-title":"Plant J"},{"key":"2026100604470474800_koag246-B27","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1111\/jipb.13275","article-title":"bZIP71 delays flowering by suppressing Ehd1 expression in rice","volume":"64","author":"Li","year":"2022","journal-title":"J Integr Plant Biol"},{"key":"2026100604470474800_koag246-B28","doi-asserted-by":"publisher","first-page":"534140","DOI":"10.1155\/2014\/534140","article-title":"Origins and evolution of WUSCHEL-related homeobox protein family in plant kingdom","volume":"2014","author":"Lian","year":"2014","journal-title":"Sci World J"},{"key":"2026100604470474800_koag246-B29","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1104\/pp.108.125542","article-title":"Ehd2, a rice ortholog of the maize INDETERMINATE1 gene, promotes flowering by up-regulating Ehd1","volume":"148","author":"Matsubara","year":"2008","journal-title":"Plant Physiol"},{"key":"2026100604470474800_koag246-B30","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1093\/pcp\/pcs028","article-title":"Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flowering","volume":"53","author":"Matsubara","year":"2012","journal-title":"Plant Cell Physiol"},{"key":"2026100604470474800_koag246-B31","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s12284-016-0107-4","article-title":"The Nipponbare genome and the next-generation of rice genomics research in Japan","volume":"9","author":"Matsumoto","year":"2016","journal-title":"Rice (N Y)"},{"key":"2026100604470474800_koag246-B32","doi-asserted-by":"publisher","first-page":"781","DOI":"10.14348\/molcells.2018.0203","article-title":"A WUSCHEL homeobox transcription factor, OsWOX13, enhances drought tolerance and triggers early flowering in rice","volume":"41","author":"Minh-Thu","year":"2018","journal-title":"Mol Cells"},{"key":"2026100604470474800_koag246-B33","doi-asserted-by":"publisher","first-page":"928055","DOI":"10.3389\/fgene.2022.928055","article-title":"Characterization of WOX genes revealed drought tolerance, callus induction, and tissue regeneration in Gossypium hirsutum","volume":"13","author":"Muhammad","year":"2022","journal-title":"Front Genet"},{"key":"2026100604470474800_koag246-B34","doi-asserted-by":"publisher","first-page":"2775","DOI":"10.1093\/molbev\/msp201","article-title":"A comprehensive classification and evolutionary analysis of plant homeobox genes","volume":"26","author":"Mukherjee","year":"2009","journal-title":"Mol Biol Evol"},{"key":"2026100604470474800_koag246-B35","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1111\/j.1365-3040.2009.02008.x","article-title":"OsMADS50 and OsMADS56 function antagonistically in regulating long day (LD)-dependent flowering in rice","volume":"32","author":"Ryu","year":"2009","journal-title":"Plant Cell Environ"},{"key":"2026100604470474800_koag246-B36","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1105\/tpc.112.101436","article-title":"The histone methyltransferase SDG724 mediates H3K36me2\/3 deposition at MADS50 and RFT1 and promotes flowering in rice","volume":"24","author":"Sun","year":"2012","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B37","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s00122-023-04476-x","article-title":"Effects of the core heading date genes Hd1, Ghd7, DTH8, and PRR37 on yield-related traits in rice","volume":"136","author":"Sun","year":"2023","journal-title":"Theor Appl Genet"},{"key":"2026100604470474800_koag246-B38","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1093\/pcp\/pcw025","article-title":"OsCOL10, a CONSTANS-like gene, functions as a flowering time repressor downstream of Ghd7 in rice","volume":"57","author":"Tan","year":"2016","journal-title":"Plant Cell Physiol"},{"key":"2026100604470474800_koag246-B39","doi-asserted-by":"publisher","first-page":"3200","DOI":"10.1111\/gcb.12250","article-title":"Single rice growth period was prolonged by cultivars shifts, but yield was damaged by climate change during 1981-2009 in China, and late rice was just opposite","volume":"19","author":"Tao","year":"2013","journal-title":"Glob Chang Biol"},{"key":"2026100604470474800_koag246-B40","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.pbi.2010.08.016","article-title":"Regulation of flowering in rice: two florigen genes, a complex gene network, and natural variation","volume":"14","author":"Tsuji","year":"2010","journal-title":"Curr Opin Plant Biol"},{"key":"2026100604470474800_koag246-B41","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1186\/gb-2009-10-12-248","article-title":"The WUS homeobox-containing (WOX) protein family","volume":"10","author":"Van der Graaff","year":"2009","journal-title":"Genome Biol"},{"key":"2026100604470474800_koag246-B42","doi-asserted-by":"publisher","DOI":"10.1101\/pdb.prot4995","article-title":"In planta visualization of protein interactions using bimolecular fluorescence complementation (BiFC)","volume":"2008","author":"Waadt","year":"2008","journal-title":"CSH Protoc"},{"key":"2026100604470474800_koag246-B43","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/s41586-018-0063-9","article-title":"Genomic variation in 3,010 diverse accessions of Asian cultivated rice","volume":"557","author":"Wang","year":"2018","journal-title":"Nature"},{"key":"2026100604470474800_koag246-B44","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1104\/pp.110.156943","article-title":"DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously","volume":"153","author":"Wei","year":"2010","journal-title":"Plant Physiol"},{"key":"2026100604470474800_koag246-B45","doi-asserted-by":"publisher","first-page":"12915","DOI":"10.1073\/pnas.0806019105","article-title":"RID1, encoding a Cys2\/His2-type zinc finger transcription factor, acts as a master switch from vegetative to floral development in rice","volume":"105","author":"Wu","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026100604470474800_koag246-B46","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jare.2022.08.001","article-title":"The clock component OsLUX regulates rice heading through recruiting OsELF3-1 and OsELF4s to repress Hd1 and Ghd7","volume":"48","author":"Xu","year":"2023","journal-title":"J Adv Res"},{"key":"2026100604470474800_koag246-B47","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/ng.143","article-title":"Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice","volume":"40","author":"Xue","year":"2008","journal-title":"Nat Genet"},{"key":"2026100604470474800_koag246-B48","doi-asserted-by":"publisher","first-page":"e96064","DOI":"10.1371\/journal.pone.0096064","article-title":"Se14, encoding a JmjC domain-containing protein, plays key roles in long-day suppression of rice flowering through the demethylation of H3K4me3 of RFT1","volume":"9","author":"Yokoo","year":"2014","journal-title":"PLoS One"},{"key":"2026100604470474800_koag246-B49","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koae309","article-title":"The DENSE AND ERECT PANICLE1-GRAIN NUMBER ASSOCIATED module enhances rice yield by repressing CYTOKININ OXIDASE 2 expression","volume":"37","author":"Zhang","year":"2025","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B50","doi-asserted-by":"publisher","first-page":"4002","DOI":"10.1093\/plcell\/koad223","article-title":"The WD40 domain-containing protein Ehd5 positively regulates flowering in rice (Oryza sativa)","volume":"35","author":"Zhang","year":"2023","journal-title":"Plant Cell"},{"key":"2026100604470474800_koag246-B51","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1746-4811-7-30","article-title":"A highly efficient rice green tissue protoplast system for transient gene expression and studying light\/chloroplast-related processes","volume":"7","author":"Zhang","year":"2011","journal-title":"Plant Methods"},{"key":"2026100604470474800_koag246-B52","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1111\/nph.13503","article-title":"Genetic interactions between diverged alleles of Early heading date 1 (Ehd1) and Heading date 3a (Hd3a)\/RICE FLOWERING LOCUS T1 (RFT1) control differential heading and contribute to regional adaptation in rice (Oryza sativa)","volume":"208","author":"Zhao","year":"2015","journal-title":"New phytol"},{"key":"2026100604470474800_koag246-B53","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1111\/jipb.12383","article-title":"Nonfunctional alleles of long-day suppressor genes independently regulate flowering time","volume":"58","author":"Zheng","year":"2016","journal-title":"J Integr Plant Biol"},{"key":"2026100604470474800_koag246-B54","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1111\/pbi.14221","article-title":"Fine-tuning rice heading date through multiplex editing of the regulatory regions of key genes by CRISPR-Cas9","volume":"22","author":"Zhou","year":"2024","journal-title":"Plant Biotechnol J"},{"key":"2026100604470474800_koag246-B55","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1093\/jxb\/erw468","article-title":"The OsHAPL1-DTH8-Hd1 complex functions as the transcription regulator to repress heading date in rice","volume":"68","author":"Zhu","year":"2017","journal-title":"J Exp Bot"}],"container-title":["The Plant Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plcell\/advance-article-pdf\/doi\/10.1093\/plcell\/koag246\/70671275\/koag246.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plcell\/article-pdf\/38\/9\/koag246\/70671275\/koag246.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plcell\/article-pdf\/38\/9\/koag246\/70671275\/koag246.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:47:13Z","timestamp":1791276433000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plcell\/article\/doi\/10.1093\/plcell\/koag246\/8762760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":55,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/plcell\/koag246","relation":{},"ISSN":["1040-4651","1532-298X"],"issn-type":[{"value":"1040-4651","type":"print"},{"value":"1532-298X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,8,17]]},"article-number":"koag246"}}