{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:44:38Z","timestamp":1791895478593,"version":"4.3.4"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The plant cell wall, composed primarily of polysaccharides, is essential for normal plant growth and development. Many of these polysaccharides are synthesized within and subsequently secreted via the endomembrane system. Mutations in genes including MURUS3 (MUR3), YPT\/RAB GTPase-interacting protein 4 homologs (YIP4a\/YIP4b), and ECHIDNA (ECH) result in dwarf plants, which is believed to be a consequence of impaired cell wall polysaccharide secretion. Here, we identify a LMBR1 (Limb Development Membrane Protein 1)-like membrane protein (LMBD2) and find that loss of LMBD2 suppresses the secretion and growth defects in the mur3, yip4a\/yip4b, and ech mutants. LMBD2 localizes to the trans-Golgi apparatus and trans-Golgi network (TGN)\/early endosome (EE), where it interacts with YIP4b and orchestrates TGN\/EE-mediated trafficking. Furthermore, LMBD2 can competitively attenuate the interaction of YIP4b and ECH. Our findings establish LMBD2 as a component of endomembrane trafficking homeostasis in plant cells and offer new insights into endomembrane dynamics and their influence on plant development.<\/jats:p>","DOI":"10.1093\/plcell\/koag310","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:56:31Z","timestamp":1791374191000},"source":"Crossref","is-referenced-by-count":0,"title":["LMBD2 interacts with components of the ECH\/YIP complex and contributes to post-Golgi trafficking in Arabidopsis"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9730-5550","authenticated-orcid":false,"given":"Meng","family":"Wang","sequence":"first","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7871-487X","authenticated-orcid":false,"given":"Zongchang","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tobacco Gene Resources, Tobacco Research Institute, Chinese Academy of Agricultural Sciences , Qingdao 266101 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7557-8283","authenticated-orcid":false,"given":"Natalie","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Cell & Systems Biology, University of Toronto , Toronto ON, M5S3B2 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9924-7780","authenticated-orcid":false,"given":"Shuaiqiang","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9443-5775","authenticated-orcid":false,"given":"Xuefeng","family":"Dou","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3330-0804","authenticated-orcid":false,"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8745-0031","authenticated-orcid":false,"given":"Yuyue","family":"Su","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1762-7533","authenticated-orcid":false,"given":"Yingyu","family":"Qu","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7886-3207","authenticated-orcid":false,"given":"Xinxin","family":"Song","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1739-075X","authenticated-orcid":false,"given":"Malcolm","family":"O\u2019Neill","sequence":"additional","affiliation":[{"name":"Complex Carbohydrate Research Center, University of Georgia , Athens, GA 30602-4712 \u00a0","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5641-7791","authenticated-orcid":false,"given":"Peter Klemmed","family":"Bj\u00f8rk","sequence":"additional","affiliation":[{"name":"Copenhagen Plant Science Center, Department Plant & Environment Science, University Copenhagen , DK-1871 Frederiksberg C, Denmark Affiliation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6377-5132","authenticated-orcid":false,"given":"Staffan","family":"Persson","sequence":"additional","affiliation":[{"name":"Copenhagen Plant Science Center, Department Plant & Environment Science, University Copenhagen , DK-1871 Frederiksberg C, Denmark Affiliation"},{"name":"Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University , Minhang 200240, Shanghai ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1820-8788","authenticated-orcid":false,"given":"Yan","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Resources and Environment, Qingdao Agricultural University , Qingdao, P R China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7447-6958","authenticated-orcid":false,"given":"Congpeng","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Landscape Architecture and Forestry, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6125-8505","authenticated-orcid":false,"given":"Dian","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8144-066X","authenticated-orcid":false,"given":"Yingzhen","family":"Kong","sequence":"additional","affiliation":[{"name":"College of Agronomy, Qingdao Agricultural University , Qingdao 266109 ,","place":["P R China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5569-5151","authenticated-orcid":false,"given":"Heather E","family":"McFarlane","sequence":"additional","affiliation":[{"name":"Department of Cell & Systems Biology, University of Toronto , Toronto ON, M5S3B2 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0771-7165","authenticated-orcid":false,"given":"Gongke","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Resources and Environment, Qingdao Agricultural University , Qingdao, P R China"},{"name":"Shandong Key Laboratory for Germplasm Innovation of Saline-alkaline Tolerant Grasses and Trees , Qingdao Agricultural University, Qingdao 266109 ,","place":["P R China"]},{"name":"Academy of Dongying Efficient Agricultural Technology and Industry on Saline and Alkaline Land in Collaboration with Qingdao Agricultural University , Dongying 257000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,13]]},"container-title":["The Plant Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plcell\/advance-article-pdf\/doi\/10.1093\/plcell\/koag310\/71904184\/koag310.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plcell\/advance-article-pdf\/doi\/10.1093\/plcell\/koag310\/71904184\/koag310.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:45:52Z","timestamp":1791891952000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plcell\/advance-article\/doi\/10.1093\/plcell\/koag310\/8913741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,13]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/plcell\/koag310","relation":{},"ISSN":["1040-4651","1532-298X"],"issn-type":[{"value":"1040-4651","type":"print"},{"value":"1532-298X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,13]]},"article-number":"koag310"}}