{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T07:32:15Z","timestamp":1767598335720,"version":"3.44.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"US\u2013Israel Binational Agricultural Research and Development Fund","award":["IS-5010-17"],"award-info":[{"award-number":["IS-5010-17"]}]},{"DOI":"10.13039\/501100023700","name":"Pears Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ovule fertilization initiates fruit set, the transition from a quiescent ovary to a growing ovary (fruit), yet how ovary growth is arrested before fertilization remains poorly understood. Previously, we have shown that the ovaries of the tomato (Solanum lycopersicum) AGAMOUS-like6 (SlAGL6) loss-of-function mutant (slagl6CR-sg1) develop normally until anthesis but nevertheless can set fruits independently of fertilization (parthenocarpy). Here, we demonstrate that SlAGL6 suppresses parthenocarpy specifically from the ovules, as reintroducing SlAGL6 into slagl6CR-sg1 using an ovule-specific promoter restored ovary arrest and eliminated parthenocarpy. A yeast 2-hybrid (Y2H) screen of a cDNA library derived from arrested and developing ovaries identified MADS-domain protein3 (SlMBP3) and MADS-domain protein22 (SlMBP22), both predominantly expressed in arrested ovary ovules, as high-confidence SlAGL6 interactors. Clustered regularly interspaced short palindromic repeats (CRISPR)\/CRISPR-associated nuclease 9 (Cas9)-mediated knockout of SlMBP3 and SlMBP22, followed by genetic interaction study involving slagl6CR-sg1, revealed that SlMBP3 acts cooperatively with SlAGL6 and SlMBP22 to suppress parthenocarpy. Protein interaction assays, together with AlphaFold-based structural predictions, revealed that SlMBP3 and SlMBP22 form homomeric and heteromeric complexes in planta, but only in the presence of SlAGL6, and that these complexes are predicted to adopt a Flower Quartet-like complex (FQC) structure. Taken together, our results establish a mechanistic framework for ovary arrest regulation, indicating that complexes containing SlAGL6, SlMBP22, and SlMBP3 operate within ovules to arrest ovary growth and prevent parthenocarpy.<\/jats:p>","DOI":"10.1093\/plphys\/kiaf363","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T11:55:56Z","timestamp":1755690956000},"source":"Crossref","is-referenced-by-count":1,"title":["MADS-BOX PROTEIN3 acts cooperatively with AGAMOUS-like6 and MADS-BOX PROTEIN22 to suppress parthenocarpy in tomato"],"prefix":"10.1093","volume":"199","author":[{"given":"Jackson","family":"Khedia","sequence":"first","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3244-3653","authenticated-orcid":false,"given":"Hawi Deressa","family":"Kenea","sequence":"additional","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]},{"name":"Department of Plant Science, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , P.O. Box 12, Rehovot 7610001 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Castaneda-M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Michigan State University , 603 Wilson Road, East Lansing, MI 48824 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Kwarteng","sequence":"additional","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]},{"name":"Department of Plant Science, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , P.O. Box 12, Rehovot 7610001 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8121-0004","authenticated-orcid":false,"given":"Daniel","family":"Feder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ortal","family":"Galsurker","sequence":"additional","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rivka","family":"Barg","sequence":"additional","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4720-7290","authenticated-orcid":false,"given":"Erich","family":"Grotewold","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Michigan State University , 603 Wilson Road, East Lansing, MI 48824 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9821-2604","authenticated-orcid":false,"given":"Tzahi","family":"Arazi","sequence":"additional","affiliation":[{"name":"Institute of Plant Sciences, Agricultural Research Organization, Volcani Institute , HaMaccabbim Road 68, Rishon LeZion 7505101 ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"issue":"8016","key":"2025091920402197600_kiaf363-B1","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1038\/s41586-024-07487-w","article-title":"Accurate structure prediction of biomolecular interactions with AlphaFold 3","volume":"630","author":"Abramson","year":"2024","journal-title":"Nature"},{"issue":"2","key":"2025091920402197600_kiaf363-B2","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1104\/pp.005223","article-title":"Down-regulation of TM29, a tomato SEPALLATA homolog, causes parthenocarpic fruit development and floral reversion","volume":"130","author":"Ampomah-Dwamena","year":"2002","journal-title":"Plant Physiol."},{"issue":"11","key":"2025091920402197600_kiaf363-B3","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1093\/jxb\/48.11.1919","article-title":"The TYLCV-tolerant tomato line MP-1 is characterized by superior transformation competence","volume":"48","author":"Barg","year":"1997","journal-title":"J Exp Bot."},{"issue":"9","key":"2025091920402197600_kiaf363-B4","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1002\/j.1537-2197.1931.tb04945.x","article-title":"Macrosporogenesis and the development of the macrogametophyte of Lycopersicon esculentum","volume":"18","author":"Cooper","year":"1931","journal-title":"Am J Bot."},{"issue":"6","key":"2025091920402197600_kiaf363-B5","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1111\/j.1365-313X.2006.02846.x","article-title":"A Bsister MADS-box gene involved in ovule and seed development in petunia and Arabidopsis","volume":"47","author":"de Folter","year":"2006","journal-title":"Plant J."},{"issue":"2","key":"2025091920402197600_kiaf363-B6","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1093\/jxb\/erq293","article-title":"The Solanum lycopersicum AUXIN RESPONSE FACTOR 7 (SlARF7) mediates cross-talk between auxin and gibberellin signalling during tomato fruit set and development","volume":"62","author":"de Jong","year":"2011","journal-title":"J Exp Bot."},{"issue":"6","key":"2025091920402197600_kiaf363-B7","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1093\/jxb\/erw046","article-title":"Flower development: the evolutionary history and functions of the AGL6 subfamily MADS-box genes","volume":"67","author":"Dreni","year":"2016","journal-title":"J Exp Bot."},{"issue":"1","key":"2025091920402197600_kiaf363-B8","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1752-0509-8-9","article-title":"Tetramer formation in Arabidopsis MADS domain proteins: analysis of a protein-protein interaction network","volume":"8","author":"Espinosa-Soto","year":"2014","journal-title":"BMC Syst Biol."},{"issue":"20","key":"2025091920402197600_kiaf363-B9","doi-asserted-by":"publisher","first-page":"6254","DOI":"10.1093\/jxb\/erad214","article-title":"Molecular, hormonal, and metabolic mechanisms of fruit set, the ovary-to-fruit transition, in horticultural crops","volume":"74","author":"Ezura","year":"2023","journal-title":"J Exp Bot."},{"issue":"3","key":"2025091920402197600_kiaf363-B10","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhae019","article-title":"Insights into the functional role of tomato TM6 as a transcriptional regulator of flower development","volume":"11","author":"Fonseca","year":"2024","journal-title":"Hortic Res."},{"issue":"6","key":"2025091920402197600_kiaf363-B11","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s11103-019-00836-8","article-title":"Downregulation of the auxin transporter gene SlPIN8 results in pollen abortion in tomato","volume":"99","author":"Gan","year":"2019","journal-title":"Plant Mol Biol."},{"issue":"10","key":"2025091920402197600_kiaf363-B12","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.2307\/3869794","article-title":"Fruits: a developmental perspective","volume":"5","author":"Gillaspy","year":"1993","journal-title":"Plant Cell."},{"issue":"6","key":"2025091920402197600_kiaf363-B13","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/gb-2010-11-6-214","article-title":"A hitchhiker's guide to the MADS world of plants","volume":"11","author":"Gramzow","year":"2010","journal-title":"Genome Biol."},{"issue":"3","key":"2025091920402197600_kiaf363-B14","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1093\/plphys\/kiaa078","article-title":"Tomato agamous-like6 parthenocarpy is facilitated by ovule integument reprogramming involving the growth regulator KLUH","volume":"185","author":"Gupta","year":"2021","journal-title":"Plant Physiol."},{"issue":"18","key":"2025091920402197600_kiaf363-B15","doi-asserted-by":"publisher","first-page":"5497","DOI":"10.1093\/jxb\/ert324","article-title":"The tomato NAC transcription factor SlNAM2 is involved in flower-boundary morphogenesis","volume":"64","author":"Hendelman","year":"2013","journal-title":"J Exp Bot."},{"issue":"1","key":"2025091920402197600_kiaf363-B16","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1038\/s41467-021-21229-w","article-title":"Multifunctional evolution of B and AGL6 MADS box genes in orchids","volume":"12","author":"Hsu","year":"2021","journal-title":"Nat Commun."},{"issue":"5","key":"2025091920402197600_kiaf363-B17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/nplants.2015.46","article-title":"Model for perianth formation in orchids","volume":"1","author":"Hsu","year":"2015","journal-title":"Nat Plants."},{"issue":"8","key":"2025091920402197600_kiaf363-B18","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1105\/tpc.18.00363","article-title":"DELLA-ARF\/IAA interaction mediates crosstalk between gibberellin and auxin signaling in controlling fruit initiation in Solanum lycopersicum","volume":"30","author":"Hu","year":"2018","journal-title":"Plant Cell."},{"issue":"5","key":"2025091920402197600_kiaf363-B19","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1038\/s41477-023-01396-y","article-title":"Four class A AUXIN RESPONSE FACTORs promote tomato fruit growth despite suppressing fruit set","volume":"9","author":"Hu","year":"2023","journal-title":"Nat Plants."},{"issue":"1","key":"2025091920402197600_kiaf363-B20","doi-asserted-by":"publisher","first-page":"6892","DOI":"10.1038\/s41467-021-27117-7","article-title":"Interaction of two MADS-box genes leads to growth phenotype divergence of all-flesh type of tomatoes","volume":"12","author":"Huang","year":"2021","journal-title":"Nat Commun."},{"issue":"11","key":"2025091920402197600_kiaf363-B21","doi-asserted-by":"publisher","first-page":"2615","DOI":"10.1093\/emboj\/19.11.2615","article-title":"Solution structure of the MEF2A\u2013DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors","volume":"19","author":"Huang","year":"2000","journal-title":"EMBO J."},{"issue":"9","key":"2025091920402197600_kiaf363-B22","doi-asserted-by":"publisher","first-page":"3435","DOI":"10.1093\/plcell\/koae151","article-title":"SEPALLATA-driven MADS transcription factor tetramerization is required for inner whorl floral organ development","volume":"36","author":"Hugouvieux","year":"2024","journal-title":"Plant Cell."},{"issue":"10","key":"2025091920402197600_kiaf363-B23","doi-asserted-by":"publisher","first-page":"4966","DOI":"10.1093\/nar\/gky205","article-title":"Tetramerization of MADS family transcription factors SEPALLATA3 and AGAMOUS is required for floral meristem determinacy in Arabidopsis","volume":"46","author":"Hugouvieux","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"2025091920402197600_kiaf363-B24","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1093\/jxb\/erx446","article-title":"The making of virgin fruit: the molecular and genetic basis of parthenocarpy","volume":"69","author":"Joldersma","year":"2018","journal-title":"J Exp Bot."},{"issue":"2","key":"2025091920402197600_kiaf363-B25","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.gene.2004.12.014","article-title":"MIKC-type MADS-domain proteins: structural modularity, protein interactions and network evolution in land plants","volume":"347","author":"Kaufmann","year":"2005","journal-title":"Gene"},{"issue":"5","key":"2025091920402197600_kiaf363-B26","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1111\/pbi.12662","article-title":"Tomato facultative parthenocarpy results from SlAGAMOUS-LIKE 6 loss of function","volume":"15","author":"Klap","year":"2017","journal-title":"Plant Biotechnol J."},{"issue":"1","key":"2025091920402197600_kiaf363-B27","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/pbi.13696","article-title":"The wheat AGL6-like MADS-box gene is a master regulator for floral organ identity and a target for spikelet meristem development manipulation","volume":"20","author":"Kong","year":"2022","journal-title":"Plant Biotechnol J."},{"issue":"6","key":"2025091920402197600_kiaf363-B28","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1111\/pbi.12069","article-title":"Early anther ablation triggers parthenocarpic fruit development in tomato","volume":"11","author":"Medina","year":"2013","journal-title":"Plant Biotechnol J."},{"issue":"7","key":"2025091920402197600_kiaf363-B29","doi-asserted-by":"publisher","first-page":"2560","DOI":"10.1105\/tpc.112.108688","article-title":"MADS domain transcription factors mediate short-range DNA looping that is essential for target gene expression in Arabidopsis","volume":"25","author":"Mendes","year":"2013","journal-title":"Plant Cell."},{"issue":"12","key":"2025091920402197600_kiaf363-B30","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.3390\/genes11121441","article-title":"How hormones and MADS-box transcription factors are involved in controlling fruit set and parthenocarpy in tomato","volume":"11","author":"Molesini","year":"2020","journal-title":"Genes (Basel)."},{"issue":"10","key":"2025091920402197600_kiaf363-B31","doi-asserted-by":"publisher","first-page":"2463","DOI":"10.1105\/tpc.004127","article-title":"The TRANSPARENT TESTA16 locus encodes the ARABIDOPSIS BSISTER MADS domain protein and is required for proper development and pigmentation of the seed coat","volume":"14","author":"Nesi","year":"2002","journal-title":"Plant Cell."},{"issue":"1","key":"2025091920402197600_kiaf363-B32","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.hpj.2023.01.002","article-title":"Histological, transcriptomic, and gene functional analyses reveal the regulatory events underlying gibberellin-induced parthenocarpy in tomato","volume":"10","author":"Niu","year":"2023","journal-title":"Horticultural Plant J"},{"issue":"2","key":"2025091920402197600_kiaf363-B33","doi-asserted-by":"publisher","first-page":"175","DOI":"10.2307\/3869637","article-title":"The TM5 MADS box gene mediates organ differentiation in the three inner whorls of tomato flowers","volume":"6","author":"Pnueli","year":"1994","journal-title":"Plant Cell."},{"issue":"9","key":"2025091920402197600_kiaf363-B34","doi-asserted-by":"publisher","first-page":"3603","DOI":"10.1105\/tpc.114.127910","article-title":"Structural basis for the oligomerization of the MADS domain transcription factor SEPALLATA3 in Arabidopsis[W]","volume":"26","author":"Puranik","year":"2014","journal-title":"Plant Cell."},{"issue":"1","key":"2025091920402197600_kiaf363-B35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-313X.2009.03917.x","article-title":"The petunia AGL6 gene has a SEPALLATA-like function in floral patterning","volume":"60","author":"Rijpkema","year":"2009","journal-title":"Plant J."},{"issue":"13","key":"2025091920402197600_kiaf363-B36","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1038\/nbt1297-1398","article-title":"Genetic engineering of parthenocarpic plants","volume":"15","author":"Rotino","year":"1997","journal-title":"Nat Biotechnol."},{"issue":"5","key":"2025091920402197600_kiaf363-B37","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msad088","article-title":"The origin of floral quartet formation\u2014ancient exon duplications shaped the evolution of MIKC-type MADS-domain transcription factor interactions","volume":"40","author":"R\u00fcmpler","year":"2023","journal-title":"Mol Biol Evol."},{"issue":"8","key":"2025091920402197600_kiaf363-B38","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.1093\/jxb\/ery063","article-title":"A conserved leucine zipper-like motif accounts for strong tetramerization capabilities of SEPALLATA-like MADS-domain transcription factors","volume":"69","author":"R\u00fcmpler","year":"2018","journal-title":"J Exp Bot."},{"issue":"7","key":"2025091920402197600_kiaf363-B39","doi-asserted-by":"publisher","first-page":"e21622","DOI":"10.1371\/journal.pone.0021622","article-title":"GoldenBraid: an iterative cloning system for standardized assembly of reusable genetic modules","volume":"6","author":"Sarrion-Perdigones","year":"2011","journal-title":"PLoS One"},{"issue":"4","key":"2025091920402197600_kiaf363-B40","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.bbrc.2010.09.108","article-title":"Rice ternary MADS protein complexes containing class B MADS heterodimer","volume":"401","author":"Seok","year":"2010","journal-title":"Biochem Biophys Res Commun."},{"issue":"38","key":"2025091920402197600_kiaf363-B41","doi-asserted-by":"publisher","first-page":"23970","DOI":"10.1073\/pnas.2011859117","article-title":"Fruit setting rewires central metabolism via gibberellin cascades","volume":"117","author":"Shinozaki","year":"2020","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"5","key":"2025091920402197600_kiaf363-B42","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1073\/pnas.1112871109","article-title":"Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development","volume":"109","author":"Smaczniak","year":"2012","journal-title":"Proc Natl Acad Sci U S A."},{"author":"Spena","key":"2025091920402197600_kiaf363-B43"},{"issue":"18","key":"2025091920402197600_kiaf363-B44","doi-asserted-by":"publisher","first-page":"3259","DOI":"10.1242\/dev.134080","article-title":"MADS-domain transcription factors and the floral quartet model of flower development: linking plant development and evolution","volume":"143","author":"Thei\u00dfen","year":"2016","journal-title":"Development (Cambridge, England)"},{"issue":"1","key":"2025091920402197600_kiaf363-B45","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1093\/jxb\/erj011","article-title":"In vivo imaging of MADS-box transcription factor interactions","volume":"57","author":"Tonaco","year":"2006","journal-title":"J Exp Bot."},{"issue":"10","key":"2025091920402197600_kiaf363-B46","doi-asserted-by":"publisher","first-page":"2676","DOI":"10.1105\/tpc.105.033415","article-title":"The tomato aux\/IAA transcription factor IAA9 is involved in fruit development and leaf morphogenesis","volume":"17","author":"Wang","year":"2005","journal-title":"The Plant Cell Online"},{"issue":"5","key":"2025091920402197600_kiaf363-B47","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1105\/tpc.108.060830","article-title":"Regulatory features underlying pollination-dependent and -independent tomato fruit set revealed by transcript and primary metabolite profiling","volume":"21","author":"Wang","year":"2009","journal-title":"Plant Cell."},{"issue":"3","key":"2025091920402197600_kiaf363-B48","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1093\/jxb\/ery418","article-title":"An AGAMOUS MADS-box protein, SlMBP3, regulates the speed of placenta liquefaction and controls seed formation in tomato","volume":"70","author":"Zhang","year":"2019","journal-title":"J Exp Bot."}],"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article-pdf\/doi\/10.1093\/plphys\/kiaf363\/64104041\/kiaf363.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/199\/1\/kiaf363\/64104041\/kiaf363.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/199\/1\/kiaf363\/64104041\/kiaf363.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:40:29Z","timestamp":1758328829000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/article\/doi\/10.1093\/plphys\/kiaf363\/8239364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,21]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/plphys\/kiaf363","relation":{},"ISSN":["0032-0889","1532-2548"],"issn-type":[{"type":"print","value":"0032-0889"},{"type":"electronic","value":"1532-2548"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,8,21]]},"article-number":"kiaf363"}}