{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:29:52Z","timestamp":1785464992081,"version":"3.56.0"},"reference-count":116,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T00:00:00Z","timestamp":1779494400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007165","name":"University of Missouri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014456","name":"Center for Bioenergy Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014456","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000015","name":"US Department of Energy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006206","name":"Office of Biological and Environmental Research in the DOE Office of Science","doi-asserted-by":"publisher","award":["ERKP886"],"award-info":[{"award-number":["ERKP886"]}],"id":[{"id":"10.13039\/100006206","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005825","name":"US Department of Agriculture National Institute of Food and Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foundational Knowledge of Plant Products program","award":["2026-67013-45667"],"award-info":[{"award-number":["2026-67013-45667"]}]},{"name":"Biorefining and Biomanufacturing program","award":["2026-67021-45696"],"award-info":[{"award-number":["2026-67021-45696"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cytosolic ascorbate peroxidases (APXs) have been proposed to have bifunctional 4-coumarate 3-hydroxylase (C3H) activity, linking redox regulation to lignin biosynthesis in plants. Although this dual role has been shown in vitro, in vivo validation remains limited. Here, we used CRISPR\/Cas9 gene editing to knock out cytosolic C3H\/APX genes in Brachypodium distachyon and poplar (Populus tremula \u00d7 Populus alba). In Brachypodium, BdC3H\/APX1 catalyzed the ascorbate-dependent hydroxylation of 4-coumarate to caffeate in vitro. Loss of BdC3H\/APX1 function led to reduced lignin content, altered monomer composition, elevated H2O2 levels, and impaired growth, while double monoallelic knockouts of BdC3H\/APX1 combined with a biallelic BdC3H\/APX2 mutation (Bdc3h\/apx1&amp;2) exhibited severe developmental defects. Exogenous caffeate and ferulate rescued the growth and lignin phenotype of the Bdc3h\/apx1 knockout mutants, whereas catalase reduced H2O2 without restoring plant growth. Similarly, CRISPR\/Cas9-mediated PtC3H\/APX1 knockout in poplar resulted in stunted growth and altered lignin composition, while the double Ptc3h\/apx1&amp;2 mutants were unable to regenerate from tissue culture. These results provide in vivo evidence of C3H\/APX bifunctionality, suggesting that perturbed lignin biosynthesis is the primary cause of the growth defects typically observed in C3H\/APX-deficient plants.<\/jats:p>","DOI":"10.1093\/plphys\/kiag293","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:45:20Z","timestamp":1779363920000},"source":"Crossref","is-referenced-by-count":1,"title":["Conserved 4-coumarate 3-hydroxylase\/ascorbate peroxidase bifunctionality coordinates lignin deposition and plant growth in\n                    <i>Brachypodium<\/i>\n                    and\n                    <i>Populus<\/i>"],"prefix":"10.1093","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2974-2186","authenticated-orcid":false,"given":"Weiwei","family":"Zhu","sequence":"first","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8685-9556","authenticated-orcid":false,"given":"Harmeet","family":"Singh-Bakala","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3129-8367","authenticated-orcid":false,"given":"Bo","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3493-3496","authenticated-orcid":false,"given":"William","family":"Bewg","sequence":"additional","affiliation":[{"name":"School of Forestry and Natural Resources, University of Georgia , Athens, GA 30602 ,","place":["United States"]},{"name":"Center for Bioenergy Innovation (CBI), Oak Ridge National Laboratory , Oak Ridge, TN 37830 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7357-917X","authenticated-orcid":false,"given":"Max","family":"Bentelspacher","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8813-2632","authenticated-orcid":false,"given":"Rachel","family":"Weber","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9739-9932","authenticated-orcid":false,"given":"Mar\u00eda \u00c1ngeles","family":"Pel\u00e1ez-Vico","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]},{"name":"Christopher S. Bond Life Sciences Center, University of Missouri , Columbia, MO 65211 \u00a0","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margot S S","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Forestry and Natural Resources, University of Georgia , Athens, GA 30602 ,","place":["United States"]},{"name":"Center for Bioenergy Innovation (CBI), Oak Ridge National Laboratory , Oak Ridge, TN 37830 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9282-7704","authenticated-orcid":false,"given":"Chung-Jui","family":"Tsai","sequence":"additional","affiliation":[{"name":"School of Forestry and Natural Resources, University of Georgia , Athens, GA 30602 ,","place":["United States"]},{"name":"Center for Bioenergy Innovation (CBI), Oak Ridge National Laboratory , Oak Ridge, TN 37830 ,","place":["United States"]},{"name":"Department of Plant Biology, University of Georgia , Athens, GA 30602 ,","place":["United States"]},{"name":"Department of Genetics, University of Georgia , Athens, GA 30602 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3192-7450","authenticated-orcid":false,"given":"Ron","family":"Mittler","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]},{"name":"Christopher S. Bond Life Sciences Center, University of Missouri , Columbia, MO 65211 \u00a0","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2293-3384","authenticated-orcid":false,"given":"Bing","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]},{"name":"Donald Danforth Plant Science Center , St.Louis, MO 63132 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9545-312X","authenticated-orcid":false,"given":"Jaime","family":"Barros","sequence":"additional","affiliation":[{"name":"Division of Plant Science and Technology, College of Agriculture Food and Natural Resources and Interdisciplinary Plant Group, University of Missouri , Columbia, MO 65211 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"2026061011332815300_kiag293-B201","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1104\/pp.105.069690","article-title":"A coumaroyl-ester-3-hydroxylase insertion mutant reveals the existence of nonredundant meta-hydroxylation pathways and essential roles for phenolic precursors in cell expansion and plant growth","volume":"140","author":"Abdulrazzak","year":"2006","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B1","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1038\/nprot.2009.30","article-title":"A protocol for Agrobacterium-mediated transformation of Brachypodium distachyon community standard line Bd21","volume":"4","author":"Alves","year":"2009","journal-title":"Nat Protoc"},{"key":"2026061011332815300_kiag293-B2","doi-asserted-by":"publisher","first-page":"19002","DOI":"10.1007\/s11356-016-7309-6","article-title":"Catalase and ascorbate peroxidase\u2014representative H2O2-detoxifying heme enzymes in plants","volume":"23","author":"Anjum","year":"2016","journal-title":"Environ Sci Pollut Res"},{"key":"2026061011332815300_kiag293-B3","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.plaphy.2018.08.007","article-title":"Evaluation and validation of housekeeping genes in two contrast species of thyme plant to drought stress using real-time PCR","volume":"132","author":"Ashrafi","year":"2018","journal-title":"Plant Physiol Biochem"},{"key":"2026061011332815300_kiag293-B202","doi-asserted-by":"crossref","first-page":"14931","DOI":"10.1021\/acs.analchem.4c07070","article-title":"Detection and analysis of reactive oxygen species (ROS): buffer components are not bystanders","volume":"97","author":"Bansal","year":"2025","journal-title":"Anal Chem"},{"key":"2026061011332815300_kiag293-B4","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1006\/anbo.1998.0655","article-title":"Hydrogen peroxide production is a general property of the lignifying xylem from vascular plants","volume":"82","author":"Barcel\u00f3","year":"1998","journal-title":"Ann Bot"},{"key":"2026061011332815300_kiag293-B5","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.tplants.2019.09.011","article-title":"Plant phenylalanine\/tyrosine ammonia-lyases","volume":"25","author":"Barros","year":"2020","journal-title":"Trends Plant Sci"},{"key":"2026061011332815300_kiag293-B6","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1038\/s41467-019-10082-7","article-title":"4-Coumarate 3-hydroxylase in the lignin biosynthesis pathway is a cytosolic ascorbate peroxidase","volume":"10","author":"Barros","year":"2019","journal-title":"Nat Commun"},{"key":"2026061011332815300_kiag293-B7","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1093\/plphys\/kiac128","article-title":"Multiplex knockout of trichome-regulating MYB duplicates in hybrid poplar using a single gRNA","volume":"189","author":"Bewg","year":"2022","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B8","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.754601","article-title":"Phenoloxidases in plants-how structural diversity enables functional specificity","volume":"12","author":"Blaschek","year":"2021","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B9","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1111\/j.1365-3040.2011.02366.x","article-title":"Role of peroxidases in the compensation of cytosolic ascorbate peroxidase knockdown in rice plants under abiotic stress","volume":"34","author":"Bonifacio","year":"2011","journal-title":"Plant Cell Environ"},{"key":"2026061011332815300_kiag293-B10","doi-asserted-by":"publisher","first-page":"17555","DOI":"10.1073\/pnas.0408024101","article-title":"Evolution of xylem lignification and hydrogel transport regulation","volume":"101","author":"Boyce","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026061011332815300_kiag293-B11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041916","article-title":"Generation and characterization of the Western Regional Research Center Brachypodium T-DNA insertional mutant collection","volume":"7","author":"Bragg","year":"2012","journal-title":"PLoS One"},{"key":"2026061011332815300_kiag293-B12","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1111\/ppl.12143","article-title":"Cytosolic APX knockdown rice plants sustain photosynthesis by regulation of protein expression related to photochemistry, Calvin cycle and photorespiration","volume":"150","author":"Carvalho","year":"2014","journal-title":"Physiol Plant"},{"key":"2026061011332815300_kiag293-B13","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1590\/S1415-47572012000600016","article-title":"Plant responses to stresses: role of ascorbate peroxidase in the antioxidant protection","volume":"35","author":"Caverzan","year":"2012","journal-title":"Genet Mol Biol"},{"key":"2026061011332815300_kiag293-B14","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.copbio.2018.12.012","article-title":"Structural features and regulation of lignin deposited upon biotic and abiotic stresses","volume":"56","author":"Cesarino","year":"2019","journal-title":"Curr Opin Biotechnol"},{"key":"2026061011332815300_kiag293-B15","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/978-1-4939-8778-8_19","article-title":"CRISPR\/Cas9 for mutagenesis in rice","volume":"1864","author":"Char","year":"2019","journal-title":"Methods Mol Biol"},{"key":"2026061011332815300_kiag293-B16","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s13068-020-01865-y","article-title":"A rapid thioacidolysis method for biomass lignin composition and tricin analysis","volume":"14","author":"Chen","year":"2021","journal-title":"Biotechnol Biofuels"},{"key":"2026061011332815300_kiag293-B17","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/oxfordjournals.pcp.a078229","article-title":"Inactivation of ascorbate peroxidase by thiols requires hydrogen peroxide","volume":"33","author":"Chen","year":"1992","journal-title":"Plant Cell Physiol"},{"key":"2026061011332815300_kiag293-B18","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.1021\/jf970055t","article-title":"Antioxidant activities of caffeic acid and its related hydroxycinnamic acid compounds","volume":"45","author":"Chen","year":"1997","journal-title":"J Agric Food Chem"},{"key":"2026061011332815300_kiag293-B19","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/tpj.13299","article-title":"Reactive oxygen species, abiotic stress and stress combination","volume":"90","author":"Choudhury","year":"2017","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B20","doi-asserted-by":"publisher","first-page":"4501","DOI":"10.1073\/pnas.0706537105","article-title":"RNAi-mediated suppression of p-coumaroyl-CoA 3\u2032-hydroxylase in hybrid poplar impacts lignin deposition and soluble secondary metabolism","volume":"105","author":"Coleman","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026061011332815300_kiag293-B21","doi-asserted-by":"publisher","first-page":"3339","DOI":"10.1093\/jxb\/ert172","article-title":"Auxin induces redox regulation of ascorbate peroxidase 1 activity by S-nitrosylation\/denitrosylation balance resulting in changes of root growth pattern in Arabidopsis","volume":"64","author":"Correa-Aragunde","year":"2013","journal-title":"J Exp Bot"},{"key":"2026061011332815300_kiag293-B22","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1111\/j.1365-313X.2010.04190.x","article-title":"H2O2 in plant peroxisomes: an in vivo analysis uncovers a Ca2+-dependent scavenging system","volume":"62","author":"Costa","year":"2010","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B23","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1006\/anbo.1993.1143","article-title":"Cytochemical localization of hydrogen peroxide in lignifying cell walls","volume":"72","author":"Czaninski","year":"1993","journal-title":"Ann Bot"},{"key":"2026061011332815300_kiag293-B24","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1104\/pp.102.2.481","article-title":"Subcellular localization of oxygen defense enzymes in soybean (Glycine max [L.] Merr.) root nodules","volume":"102","author":"Dalton","year":"1993","journal-title":"Plant Phys"},{"key":"2026061011332815300_kiag293-B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/abbi.1996.0135","article-title":"Heterologous expression and characterization of soybean cytosolic ascorbate peroxidase","volume":"328","author":"Dalton","year":"1996","journal-title":"Arch Biochem Biophys"},{"key":"2026061011332815300_kiag293-B26","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1105\/tpc.104.026971","article-title":"Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis","volume":"17","author":"Davletova","year":"2005","journal-title":"Plant Cell"},{"key":"2026061011332815300_kiag293-B27","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1038\/s41587-020-0703-0","article-title":"A GRF-GIF chimeric protein improves the regeneration efficiency of transgenic plants","volume":"38","author":"Debernardi","year":"2020","journal-title":"Nat Biotechnol"},{"key":"2026061011332815300_kiag293-B28","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.190215","article-title":"Lignin biosynthesis: old roads revisited and new roads explored","volume":"9","author":"Dixon","year":"2019","journal-title":"Open Biol"},{"key":"2026061011332815300_kiag293-B29","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1146\/annurev-arplant-062923-022602","article-title":"Enabling lignin valorization through integrated advances in plant biology and biorefining","volume":"75","author":"Dixon","year":"2024","journal-title":"Annu Rev Plant Biol"},{"key":"2026061011332815300_kiag293-B30","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1111\/j.1399-3054.1982.tb00696.x","article-title":"Lack of involvement of polyphenol oxidase in ortho-hydroxylation of phenolic compounds in mung bean seedlings","volume":"54","author":"Duke","year":"1982","journal-title":"Physiol Plant"},{"key":"2026061011332815300_kiag293-B31","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/j.1469-8137.2007.01995.x","article-title":"Distribution of superoxide and hydrogen peroxide in Arabidopsis root and their influence on root development: possible interaction with peroxidases","volume":"174","author":"Dunand","year":"2007","journal-title":"New Phytol"},{"key":"2026061011332815300_kiag293-B32","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1111\/tpj.14685","article-title":"Rapid systemic signaling during abiotic and biotic stresses: is the ROS wave master of all trades?","volume":"102","author":"Fichman","year":"2020","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B33","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1046\/j.1365-313X.2002.01267.x","article-title":"Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis","volume":"30","author":"Franke","year":"2002","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B34","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1046\/j.1365-313X.2002.01266.x","article-title":"The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism","volume":"30","author":"Franke","year":"2002","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B35","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2019103894","article-title":"SCHENGEN receptor module drives localized ROS production and lignification in plant roots","volume":"39","author":"Fujita","year":"2020","journal-title":"EMBO J"},{"key":"2026061011332815300_kiag293-B36","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.00446","article-title":"Cytosolic ascorbate peroxidases plays a critical role in photosynthesis by modulating reactive oxygen species level in stomatal guard cell","volume":"11","author":"Guo","year":"2020","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B37","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1111\/j.1365-3040.2011.02442.x","article-title":"Convergence and divergence in gene expression profiles induced by leaf senescence and 27 senescence-promoting hormonal, pathological and environmental stress treatments","volume":"35","author":"Guo","year":"2012","journal-title":"Plant Cell Environ"},{"key":"2026061011332815300_kiag293-B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2023.100741","article-title":"Modularly assembled multiplex prime editors for simultaneous editing of agronomically important genes in rice","volume":"5","author":"Gupta","year":"2024","journal-title":"Plant Commun"},{"key":"2026061011332815300_kiag293-B39","first-page":"95","article-title":"BIOEDIT: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT","volume":"41","author":"Hall","year":"1999","journal-title":"Nucleic Acids Symp Ser."},{"key":"2026061011332815300_kiag293-B40","doi-asserted-by":"publisher","first-page":"10360","DOI":"10.1021\/bi0106033","article-title":"Cationic ascorbate peroxidase isoenzyme II from tea: structural insights into the heme pocket of a unique hybrid peroxidase","volume":"40","author":"Heering","year":"2001","journal-title":"Biochemistry"},{"key":"2026061011332815300_kiag293-B203","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/0014-5793(86)81230-3","article-title":"Rate constants for reaction of hydroxyl radicals with Tris, Tricine and Hepes buffers","volume":"199","author":"Hicks","year":"1986","journal-title":"FEBS Lett"},{"key":"2026061011332815300_kiag293-B41","doi-asserted-by":"publisher","first-page":"4062","DOI":"10.1016\/j.biortech.2009.12.145","article-title":"Changes of microbial population structure related to lignin degradation during lignocellulosic waste composting","volume":"101","author":"Huang","year":"2010","journal-title":"Bioresour Technol"},{"key":"2026061011332815300_kiag293-B42","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.00800","article-title":"Mechanisms of ROS regulation of plant development and stress responses","volume":"10","author":"Huang","year":"2019","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B43","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.molcel.2014.02.021","article-title":"Direct regulation of the NADPH oxidase RBOHD by the PRR-associated kinase BIK1 during plant immunity","volume":"54","author":"Kadota","year":"2014","journal-title":"Mol Cell"},{"key":"2026061011332815300_kiag293-B44","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1093\/plphys\/kiae287","article-title":"Extracellular vesicles of Norway spruce contain precursors and enzymes for lignin formation and salicylic acid","volume":"196","author":"Kankaanp\u00e4\u00e4","year":"2024","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B45","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s10327-006-0283-y","article-title":"Pea extracellular Cu\/Zn-superoxide dismutase responsive to signal molecules from a fungal pathogen","volume":"72","author":"Kasai","year":"2006","journal-title":"J Gen Plant Pathol"},{"key":"2026061011332815300_kiag293-B46","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/s13205-019-1924-0","article-title":"Deciphering hydrogen peroxide-induced signalling towards stress tolerance in plants","volume":"9","author":"Khedia","year":"2019","journal-title":"3 Biotech"},{"key":"2026061011332815300_kiag293-B47","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s11816-021-00660-x","article-title":"Downregulation of swpa4 peroxidase expression in transgenic sweetpotato plants decreases abiotic stress tolerance and reduces stress-related peroxidase expression","volume":"15","author":"Kim","year":"2021","journal-title":"Plant Biotechnol Rep"},{"key":"2026061011332815300_kiag293-B48","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1093\/oxfordjournals.jbchem.a122651","article-title":"Detection and characterization of p-coumaric acid hydroxylase in mung bean, Vigna mungo, seedlings","volume":"105","author":"Kojima","year":"1989","journal-title":"J Biochem"},{"key":"2026061011332815300_kiag293-B49","doi-asserted-by":"publisher","first-page":"34197","DOI":"10.1074\/jbc.M806337200","article-title":"Ascorbate peroxidase 1 plays a key role in the response of Arabidopsis thaliana to stress combination","volume":"283","author":"Koussevitzky","year":"2008","journal-title":"J Biol Chem"},{"key":"2026061011332815300_kiag293-B50","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3390\/antiox10010065","article-title":"Arabidopsis APx-R is a plastidial ascorbate-independent peroxidase regulated by photomorphogenesis","volume":"10","author":"Lazzarotto","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"2026061011332815300_kiag293-B51","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1093\/mp\/ssu044","article-title":"CRISPR-P: a web tool for synthetic single-guide RNA design of CRISPR-system in plants","volume":"7","author":"Lei","year":"2014","journal-title":"Mol Plant"},{"key":"2026061011332815300_kiag293-B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2023.102789","article-title":"Novel insight into functions of ascorbate peroxidase in higher plants: more than a simple antioxidant enzyme","volume":"64","author":"Li","year":"2023","journal-title":"Redox Biol"},{"key":"2026061011332815300_kiag293-B53","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2014.00745","article-title":"A simple, rapid, and reliable protocol to localize hydrogen peroxide in large plant organs by DAB-mediated tissue printing","volume":"5","author":"Liu","year":"2014","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B54","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1016\/j.tibtech.2022.09.014","article-title":"Creative biological lignin conversion routes toward lignin valorization","volume":"40","author":"Liu","year":"2022","journal-title":"Trends Biotechnol"},{"key":"2026061011332815300_kiag293-B55","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1093\/jxb\/ern278","article-title":"The role of xylem class III peroxidases in lignification","volume":"60","author":"Marjamaa","year":"2009","journal-title":"J Exp Bot"},{"key":"2026061011332815300_kiag293-B56","doi-asserted-by":"publisher","first-page":"4877","DOI":"10.1093\/plcell\/koac284","article-title":"Plant biomechanics and resilience to environmental changes are controlled by specific lignin chemistries in each vascular cell type and morphotype","volume":"34","author":"M\u00e9nard","year":"2022","journal-title":"Plant Cell"},{"key":"2026061011332815300_kiag293-B57","doi-asserted-by":"publisher","DOI":"10.1242\/dev.164376","article-title":"Reactive oxygen species in plant development","volume":"145","author":"Mhamdi","year":"2018","journal-title":"Development"},{"key":"2026061011332815300_kiag293-B58","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1104\/pp.107.101436","article-title":"Double mutants deficient in cytosolic and thylakoid ascorbate peroxidase reveal a complex mode of interaction between reactive oxygen species, plant development, and response to abiotic stresses","volume":"144","author":"Miller","year":"2007","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B59","first-page":"101","volume-title":"Ascorbate peroxidase: antioxidants and reactive oxygen species in plants","author":"Mittler","year":"2005"},{"key":"2026061011332815300_kiag293-B60","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1038\/s41580-022-00499-2","article-title":"Reactive oxygen species signalling in plant stress responses","volume":"23","author":"Mittler","year":"2022","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2026061011332815300_kiag293-B61","doi-asserted-by":"publisher","first-page":"21802","DOI":"10.1016\/S0021-9258(19)36683-9","article-title":"Molecular cloning and characterization of a gene encoding pea cytosolic ascorbate peroxidase","volume":"267","author":"Mittler","year":"1992","journal-title":"J Biol Chem"},{"key":"2026061011332815300_kiag293-B62","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1038\/s41477-021-00991-1","article-title":"Precise plant genome editing using base editors and prime editors","volume":"7","author":"Molla","year":"2021","journal-title":"Nat Plants"},{"key":"2026061011332815300_kiag293-B63","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110000","article-title":"The acetyl bromide method is faster, simpler and presents best recovery of lignin in different herbaceous tissues than Klason and thioglycolic acid methods","volume":"9","author":"Moreira-Vilar","year":"2014","journal-title":"PLoS One"},{"key":"2026061011332815300_kiag293-B64","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1093\/oxfordjournals.pcp.a029014","article-title":"Intra-and extra-cellular localization of \u201ccytosolic\u201d CuZn-superoxide dismutase in spinach leaf and hypocotyl","volume":"37","author":"Ogawa","year":"1996","journal-title":"Plant Cell Physiol"},{"key":"2026061011332815300_kiag293-B65","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1105\/tpc.001487","article-title":"Polymerization of monolignols by redox shuttle\u2013mediated enzymatic oxidation: a new model in lignin biosynthesis I","volume":"14","author":"Onnerud","year":"2002","journal-title":"Plant Cell"},{"key":"2026061011332815300_kiag293-B66","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1111\/nph.18624","article-title":"In vitro floral development in poplar: insights into seed trichome regulation and trimonoecy","volume":"237","author":"Ortega","year":"2022","journal-title":"New Phytol"},{"key":"2026061011332815300_kiag293-B67","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.00537","article-title":"Impact of combined abiotic and biotic stresses on plant growth and avenues for crop improvement by exploiting physio-morphological traits","volume":"8","author":"Pandey","year":"2017","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B68","doi-asserted-by":"publisher","DOI":"10.4172\/2161-1009.1000308","article-title":"A comprehensive review on function and application of plant peroxidases","volume":"6","author":"Pandey","year":"2017","journal-title":"Biochem Anal Biochem"},{"key":"2026061011332815300_kiag293-B69","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2023.1189020","article-title":"Genome-wide characterization of ascorbate peroxidase gene family in pepper (Capsicum annuum L.) in response to multiple abiotic stresses","volume":"14","author":"Pang","year":"2023","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B70","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1046\/j.1365-313X.2003.01715.x","article-title":"Growth suppression, altered stomatal responses, and augmented induction of heat shock proteins in cytosolic ascorbate peroxidase (Apx1)-deficient Arabidopsis plants","volume":"34","author":"Pnueli","year":"2003","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B71","doi-asserted-by":"publisher","DOI":"10.3791\/51381","article-title":"Histochemical staining of Arabidopsis thaliana secondary cell wall elements","volume":"13","author":"Pradhan Mitra","year":"2014","journal-title":"J Vis Exp"},{"key":"2026061011332815300_kiag293-B72","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.ab.2007.01.005","article-title":"A plate reader method for the measurement of NAD, NADP, glutathione, and ascorbate in tissue extracts: application to redox profiling during Arabidopsis rosette development","volume":"363","author":"Queval","year":"2007","journal-title":"Anal Biochem"},{"key":"2026061011332815300_kiag293-B73","doi-asserted-by":"publisher","DOI":"10.1126\/science.1246843","article-title":"Lignin valorization: improving lignin processing in the biorefinery","volume":"344","author":"Ragauskas","year":"2014","journal-title":"Science"},{"key":"2026061011332815300_kiag293-B74","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1007\/s12155-012-9218-y","article-title":"Effects on lignin structure of coumarate 3-hydroxylase downregulation in poplar","volume":"5","author":"Ralph","year":"2012","journal-title":"Bioenergy Res"},{"key":"2026061011332815300_kiag293-B75","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21239149","article-title":"Use of H2O2 to cause oxidative stress, the catalase issue","volume":"21","author":"Ransy","year":"2020","journal-title":"Int J Mol Sci"},{"key":"2026061011332815300_kiag293-B76","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1042\/bss0710027","article-title":"Defining substrate specificity and catalytic mechanism in ascorbate peroxidase","volume":"71","author":"Raven","year":"2004","journal-title":"Biochem Soc Symp"},{"key":"2026061011332815300_kiag293-B77","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1038\/s41467-021-22550-0","article-title":"Two chemically distinct root lignin barriers control solute and water balance","volume":"12","author":"Reyt","year":"2021","journal-title":"Nat Commun"},{"key":"2026061011332815300_kiag293-B78","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.plantsci.2017.07.009","article-title":"Rice peroxisomal ascorbate peroxidase knockdown affects ROS signaling and triggers early leaf senescence","volume":"263","author":"Ribeiro","year":"2017","journal-title":"Plant Sci"},{"key":"2026061011332815300_kiag293-B79","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1104\/pp.16.00163","article-title":"Production and scavenging of reactive oxygen species and redox signaling during leaf and flower senescence: similar but different","volume":"171","author":"Rogers","year":"2016","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B80","doi-asserted-by":"publisher","first-page":"29166","DOI":"10.1073\/pnas.2012728117","article-title":"High-order mutants reveal an essential requirement for peroxidases but not laccases in Casparian strip lignification","volume":"117","author":"Rojas-Murcia","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026061011332815300_kiag293-B81","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.phytochem.2010.01.003","article-title":"Cytosolic APx knockdown indicates an ambiguous redox responses in rice","volume":"71","author":"Rosa","year":"2010","journal-title":"Phytochemistry"},{"key":"2026061011332815300_kiag293-B82","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1111\/j.1365-313X.2009.03996.x","article-title":"Mutations in the cinnamate 4-hydroxylase gene impact metabolism, growth and development in Arabidopsis","volume":"60","author":"Schilmiller","year":"2009","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B83","doi-asserted-by":"publisher","first-page":"36566","DOI":"10.1074\/jbc.M104047200","article-title":"CYP98A3 from Arabidopsis thaliana is a 3\u2032-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway","volume":"276","author":"Schoch","year":"2001","journal-title":"J Biol Chem"},{"key":"2026061011332815300_kiag293-B84","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1093\/mp\/sst079","article-title":"Organelle pH in the Arabidopsis endomembrane system","volume":"6","author":"Shen","year":"2013","journal-title":"Mol Plant"},{"key":"2026061011332815300_kiag293-B85","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1093\/jexbot\/53.372.1305","article-title":"Regulation and function of ascorbate peroxidase isoenzymes","volume":"53","author":"Shigeoka","year":"2002","journal-title":"J Exp Bot"},{"key":"2026061011332815300_kiag293-B86","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.908649","article-title":"Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification-associated pleiotropic effects","volume":"13","author":"Shrestha","year":"2022","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B87","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.14388","article-title":"Ascorbate, plant hormones and their interactions during plant responses to biotic stress","volume":"176","author":"Singh","year":"2024","journal-title":"Physiol Plant"},{"key":"2026061011332815300_kiag293-B88","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1093\/jxb\/ers335","article-title":"Enhanced seed production under prolonged heat stress conditions in Arabidopsis thaliana plants deficient in cytosolic ascorbate peroxidase 2","volume":"64","author":"Suzuki","year":"2013","journal-title":"J Exp Bot"},{"key":"2026061011332815300_kiag293-B89","doi-asserted-by":"publisher","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol Biol Evol"},{"key":"2026061011332815300_kiag293-B90","doi-asserted-by":"publisher","first-page":"4876","DOI":"10.1093\/nar\/25.24.4876","article-title":"The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools","volume":"25","author":"Thompson","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"2026061011332815300_kiag293-B91","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1046\/j.1365-313X.1997.11061187.x","article-title":"Subcellular localization of H2O2 in plants. H2O2 accumulation in papillae and hypersensitive response during the barley\u2014powdery mildew interaction","volume":"11","author":"Thordal-Christensen","year":"1997","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B92","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1038\/s41467-018-03463-x","article-title":"Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor","volume":"9","author":"Tian","year":"2018","journal-title":"Nat Commun"},{"key":"2026061011332815300_kiag293-B93","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.copbio.2018.10.001","article-title":"Lignin polymerization: how do plants manage the chemistry so well?","volume":"56","author":"Tobimatsu","year":"2019","journal-title":"Curr Opin Biotechnol"},{"key":"2026061011332815300_kiag293-B94","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1073\/pnas.1018359108","article-title":"Extranuclear protection of chromosomal DNA from oxidative stress","volume":"108","author":"Vanderauwera","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026061011332815300_kiag293-B95","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.copbio.2019.02.018","article-title":"Lignin biosynthesis and its integration into metabolism","volume":"56","author":"Vanholme","year":"2019","journal-title":"Curr Opin Biotechnol"},{"key":"2026061011332815300_kiag293-B96","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1042\/bj1190089","article-title":"The action of o-dihydric phenols in the hydroxylation of p-coumaric acid by a phenolase from leaves of spinach beet (Beta vulgaris L.)","volume":"119","author":"Vaughan","year":"1970","journal-title":"Biochem J"},{"key":"2026061011332815300_kiag293-B97","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/s00299-007-0472-y","article-title":"High-efficiency Agrobacterium-mediated transformation of Brachypodium distachyon inbred line Bd21-3","volume":"27","author":"Vogel","year":"2008","journal-title":"Plant Cell Rep"},{"key":"2026061011332815300_kiag293-B98","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01523","article-title":"Peroxidases bound to the growing lignin polymer produce natural like extracellular lignin in a cell culture of Norway spruce","volume":"7","author":"Warinowski","year":"2016","journal-title":"Front Plant Sci"},{"key":"2026061011332815300_kiag293-B99","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1016\/j.molp.2015.06.001","article-title":"AGEseq: analysis of genome editing by sequencing","volume":"8","author":"Xue","year":"2015","journal-title":"Mol Plant"},{"key":"2026061011332815300_kiag293-B100","doi-asserted-by":"publisher","first-page":"6652","DOI":"10.1007\/s00344-023-10926-z","article-title":"Lignin: the building block of defense responses to stress in plants","volume":"42","author":"Yadav","year":"2023","journal-title":"J Plant Growth Regul"},{"key":"2026061011332815300_kiag293-B101","doi-asserted-by":"publisher","first-page":"2700","DOI":"10.1093\/jxb\/erae061","article-title":"Physiological function and regulation of ascorbate peroxidase isoforms","volume":"75","author":"Yoshimura","year":"2024","journal-title":"J Exp Bot"},{"key":"2026061011332815300_kiag293-B102","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1105\/tpc.008680","article-title":"Nicotiana benthamiana gp91phox homologs NbrbohA and NbrbohB participate in H2O2 accumulation and resistance to Phytophthora infestans","volume":"15","author":"Yoshioka","year":"2003","journal-title":"Plant Cell"},{"key":"2026061011332815300_kiag293-B103","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s11658-021-00300-w","article-title":"Specificity of H2O2 signaling in leaf senescence: is the ratio of H2O2 contents in different cellular compartments sensed in Arabidopsis plants?","volume":"27","author":"Zentgraf","year":"2022","journal-title":"Cell Mol Biol Lett"},{"key":"2026061011332815300_kiag293-B104","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021778","article-title":"Activity of cytosolic ascorbate peroxidase (APX) from Panicum virgatum against ascorbate and phenylpropanoids","volume":"24","author":"Zhang","year":"2023","journal-title":"Int J Mol Sci"},{"key":"2026061011332815300_kiag293-B105","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1093\/plphys\/kiac604","article-title":"A sorghum ascorbate peroxidase with four binding sites has activity against ascorbate and phenylpropanoids","volume":"192","author":"Zhang","year":"2023","journal-title":"Plant Physiol"},{"key":"2026061011332815300_kiag293-B106","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1038\/s41477-022-01181-3","article-title":"PtomtAPX is an autonomous lignification peroxidase during the earliest stage of secondary wall formation in Populus tomentosa Carr","volume":"8","author":"Zhang","year":"2022","journal-title":"Nat Plants"},{"key":"2026061011332815300_kiag293-B107","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057472","article-title":"Gene knockout study reveals that cytosolic ascorbate peroxidase 2 (OsAPX2) plays a critical role in growth and reproduction in rice under drought, salt and cold stresses","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"key":"2026061011332815300_kiag293-B108","doi-asserted-by":"publisher","first-page":"3976","DOI":"10.1105\/tpc.113.117770","article-title":"Laccase is necessary and nonredundant with peroxidase for lignin polymerization during vascular development in Arabidopsis","volume":"25","author":"Zhao","year":"2013","journal-title":"Plant Cell"},{"key":"2026061011332815300_kiag293-B109","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1111\/tpj.16454","article-title":"Haplotype-resolved genome assembly of Populus tremula \u00d7 P. alba reveals aspen-specific megabase satellite DNA","volume":"116","author":"Zhou","year":"2023","journal-title":"Plant J"},{"key":"2026061011332815300_kiag293-B110","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1093\/treephys\/tpaf081","article-title":"Populus VariantDB v3. 2 facilitates CRISPR and functional genomics research","volume":"45","author":"Zhou","year":"2025","journal-title":"Tree Physiol"},{"key":"2026061011332815300_kiag293-B111","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.70607","article-title":"Tissue-specific developmental changes in lignin deposition in model plants","volume":"177","author":"Zhu","year":"2025","journal-title":"Physiol Plant"},{"key":"2026061011332815300_kiag293-B112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2503491122","article-title":"Factors underlying a latitudinal gradient in the S\/G lignin monomer ratio in natural poplar variants","volume":"122","author":"Zhu","year":"2025","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026061011332815300_kiag293-B113","first-page":"515","article-title":"The correlation between oxidative stress and leaf senescence during plant development","volume":"10","author":"Zimmermann","year":"2005","journal-title":"Cell Mol Biol Lett"}],"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article-pdf\/doi\/10.1093\/plphys\/kiag293\/68372170\/kiag293.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/201\/2\/kiag293\/68372170\/kiag293.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/201\/2\/kiag293\/68372170\/kiag293.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:33:35Z","timestamp":1781105615000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/article\/doi\/10.1093\/plphys\/kiag293\/8691101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":116,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6,2]]}},"URL":"https:\/\/doi.org\/10.1093\/plphys\/kiag293","relation":{},"ISSN":["0032-0889","1532-2548"],"issn-type":[{"value":"0032-0889","type":"print"},{"value":"1532-2548","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,5,22]]},"article-number":"kiag293"}}