{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T19:12:01Z","timestamp":1788549121841,"version":"build-2803163510"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32472577"],"award-info":[{"award-number":["32472577"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32522089"],"award-info":[{"award-number":["32522089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Yunnan Key Laboratory of Plant Pathology","award":["szbkf2024006"],"award-info":[{"award-number":["szbkf2024006"]}]},{"name":"Key Laboratory of Herbage and Endemic Crop Biology"},{"DOI":"10.13039\/100009122","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009122","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009381","name":"IMU","doi-asserted-by":"publisher","award":["HECB2024OF03"],"award-info":[{"award-number":["HECB2024OF03"]}],"id":[{"id":"10.13039\/501100009381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004763","name":"Natural Science Foundation of Inner Mongolia Autonomous Region","doi-asserted-by":"publisher","award":["2023ZD14"],"award-info":[{"award-number":["2023ZD14"]}],"id":[{"id":"10.13039\/501100004763","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Innovative Research Team in Universities of Inner Mongolia Autonomous Region","award":["NMGIRT2410"],"award-info":[{"award-number":["NMGIRT2410"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The reactive oxygen species (ROS) burst is a hallmark of immune responses, and its fine-tuned regulation is essential for balancing plant immunity and growth. Although mechanistic understanding of ROS production has improved in Arabidopsis, corresponding knowledge remains sparse in crops, particularly in the non-Brassicaceae species that lack PBL13-mediated negative regulation of the ROS burst. Here, we report an RLCK-V subfamily member in potato, StSOAK1, which negatively regulates disease resistance to the oomycete Phytophthora infestans and the fungus Botrytis cinerea. Furthermore, the potato stsoak1 mutants displayed elevated ROS production upon pathogen infection and immune activation. StSOAK1 interacts with and directly phosphorylates the ROS-producing enzyme StRBOHB at Ser849. Notably, the StSOAK1-StRBOHB complex exhibits dynamic changes upon immune activation. Moreover, the phosphorylation status of the S849 site is essential for StRBOHB protein stability and the function of StRBOHB in regulating ROS burst. Together, our study reveals a regulatory mechanism of potato StRBOHB, which occurs in parallel with its paradigmatic AtPBL13-mediated regulation in Arabidopsis.<\/jats:p>","DOI":"10.1093\/plphys\/kiag558","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:53:11Z","timestamp":1785412391000},"source":"Crossref","is-referenced-by-count":0,"title":["Gene editing of the transmembrane kinase SOAK1 fine-tunes reactive oxygen species production for enhanced disease resistance in potato"],"prefix":"10.1093","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6147-2796","authenticated-orcid":false,"given":"Yingying","family":"Song","sequence":"first","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1654-4908","authenticated-orcid":false,"given":"Yongming","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]},{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Plant Immunity Center, Fujian Agriculture and Forestry University , Fuzhou 350002 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3608-1477","authenticated-orcid":false,"given":"Jiayuan","family":"Qin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4541-9852","authenticated-orcid":false,"given":"Xiuli","family":"Qin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6214-2863","authenticated-orcid":false,"given":"Zhipeng","family":"Tu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0342-2588","authenticated-orcid":false,"given":"Jiaxin","family":"Pan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Li","sequence":"additional","affiliation":[{"name":"Dingxi Potato Research Institute , Dingxi, Gansu Province 743000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyong","family":"Xue","sequence":"additional","affiliation":[{"name":"Dingxi Potato Research Institute , Dingxi, Gansu Province 743000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Decai","family":"Yu","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Plant Pathology, Yunnan Agricultural University , Kunming 650201 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences\/the Key Laboratory of Biology and Genetic Improvement of Oil Crops, The Ministry of Agriculture and Rural Affairs, Wuhan 430062 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5387-2748","authenticated-orcid":false,"given":"Xiaodan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-6642","authenticated-orcid":false,"given":"Daolong","family":"Dou","sequence":"additional","affiliation":[{"name":"College of Plant Protection, Nanjing Agricultural University , Nanjing 210095 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0524-6355","authenticated-orcid":false,"given":"Jianjian","family":"Qi","sequence":"additional","affiliation":[{"name":"Potato Engineering and Technology Research Centre, Key Laboratory of Herbage and Endemic Crop Biology, Ministry of Education, Inner Mongolia University , Hohhot 010021 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0355-9611","authenticated-orcid":false,"given":"Guangyuan","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, Ministry of Agriculture Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University , Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"2026090414222912900_kiag558-B1","doi-asserted-by":"publisher","first-page":"2645","DOI":"10.1105\/tpc.15.00213","article-title":"WRKY transcription factors phosphorylated by MAPK regulate a plant immune NADPH oxidase in Nicotiana benthamiana","volume":"27","author":"Adachi","year":"2015","journal-title":"Plant Cell"},{"key":"2026090414222912900_kiag558-B2","doi-asserted-by":"publisher","first-page":"102276","DOI":"10.1016\/j.pbi.2022.102276","article-title":"Connecting the dots between cell surface- and intracellular-triggered immune pathways in plants","volume":"69","author":"Bernoux","year":"2022","journal-title":"Curr Opin Plant Biol."},{"key":"2026090414222912900_kiag558-B3","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1038\/s41477-022-01252-5","article-title":"The cytosolic thiol peroxidase PRXIIB is an intracellular sensor for H2O2 that regulates plant immunity through a redox relay","volume":"8","author":"Bi","year":"2022","journal-title":"Nat Plants"},{"key":"2026090414222912900_kiag558-B4","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/pbi.14175","article-title":"CRISPR\/Cas9-guided editing of a novel susceptibility gene in potato improves Phytophthora resistance without growth penalty","volume":"22","author":"Bi","year":"2024","journal-title":"Plant Biotechnol J"},{"key":"2026090414222912900_kiag558-B5","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.1111\/jipb.13876","article-title":"Potato DMP2 positively regulates plant immunity by modulating endoplasmic reticulum homeostasis","volume":"67","author":"Bi","year":"2025","journal-title":"J Integr Plant Biol"},{"key":"2026090414222912900_kiag558-B6","doi-asserted-by":"publisher","first-page":"e25114","DOI":"10.7554\/eLife.25114","article-title":"Plant immune and growth receptors share common signalling components but localise to distinct plasma membrane nanodomains","volume":"6","author":"B\u00fccherl","year":"2017","journal-title":"eLife"},{"key":"2026090414222912900_kiag558-B7","doi-asserted-by":"publisher","first-page":"koaf049","DOI":"10.1093\/plcell\/koaf049","article-title":"Gene editing of the E3 ligase PIRE1 fine-tunes reactive oxygen species production for enhanced bacterial disease resistance in tomato","volume":"37","author":"Castro","year":"2025","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B8","doi-asserted-by":"publisher","first-page":"2265","DOI":"10.1038\/s41467-017-02340-3","article-title":"Extracellular ATP elicits DORN1-mediated RBOHD phosphorylation to regulate stomatal aperture","volume":"8","author":"Chen","year":"2017","journal-title":"Nat Commun"},{"key":"2026090414222912900_kiag558-B9","doi-asserted-by":"publisher","first-page":"eadt2315","DOI":"10.1126\/sciadv.adt2315","article-title":"Reciprocal phosphorylation between SOAK1 and SOBIR1 fine-tunes receptor-like protein (RLP)-mediated plant immunity","volume":"11","author":"Chen","year":"2025","journal-title":"Sci Adv"},{"key":"2026090414222912900_kiag558-B10","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1038\/nature05999","article-title":"A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence","volume":"448","author":"Chinchilla","year":"2007","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B11","doi-asserted-by":"publisher","first-page":"8744","DOI":"10.1073\/pnas.1221294110","article-title":"Calcium-dependent protein kinase\/NADPH oxidase activation circuit is required for rapid defense signal propagation","volume":"110","author":"Dubiella","year":"2013","journal-title":"Proc Natl Acad Sci U S A."},{"key":"2026090414222912900_kiag558-B12","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.copbio.2021.05.005","article-title":"Stop helping pathogens: engineering plant susceptibility genes for durable resistance","volume":"70","author":"Garcia-Ruiz","year":"2021","journal-title":"Curr Opin Biotechnol."},{"key":"2026090414222912900_kiag558-B13","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/nature08358","article-title":"Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans","volume":"461","author":"Haas","year":"2009","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B14","doi-asserted-by":"publisher","first-page":"100050","DOI":"10.1016\/j.xplc.2020.100050","article-title":"All roads lead to susceptibility: the many modes of action of fungal and oomycete intracellular effectors","volume":"1","author":"He","year":"2020","journal-title":"Plant Commun."},{"key":"2026090414222912900_kiag558-B15","doi-asserted-by":"publisher","first-page":"6494","DOI":"10.1074\/jbc.M608966200","article-title":"Novel mechanism of activation of NADPH oxidase 5. Calcium sensitization via phosphorylation","volume":"282","author":"Jagnandan","year":"2007","journal-title":"J Biol Chem"},{"key":"2026090414222912900_kiag558-B16","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.molcel.2014.02.021","article-title":"Direct regulation of the NADPH oxidase RBOHD by the PRR-associated kinase BIK1 during plant immunity","volume":"54","author":"Kadota","year":"2014","journal-title":"Mol Cell"},{"key":"2026090414222912900_kiag558-B17","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1105\/tpc.19.00525","article-title":"CRK2 and C-terminal phosphorylation of NADPH oxidase RBOHD regulate reactive oxygen Species production in Arabidopsis","volume":"32","author":"Kimura","year":"2020","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B18","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1105\/tpc.106.048884","article-title":"Calcium-dependent protein kinases regulate the production of reactive oxygen Species by potato NADPH oxidase","volume":"19","author":"Kobayashi","year":"2007","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B19","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1093\/jxb\/erj113","article-title":"Subcellular localization of Strboh proteins and NADPH-dependent O2-generating activity in potato tuber tissues","volume":"57","author":"Kobayashi","year":"2006","journal-title":"J Exp Bot."},{"key":"2026090414222912900_kiag558-B20","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.cell.2023.12.030","article-title":"Dual phosphorylation of DGK5-mediated PA burst regulates ROS in plant immunity","volume":"187","author":"Kong","year":"2024","journal-title":"Cell"},{"key":"2026090414222912900_kiag558-B21","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.tplants.2021.07.018","article-title":"Susceptibility reversed: modified plant susceptibility genes for resistance to bacteria","volume":"27","author":"Koseoglou","year":"2022","journal-title":"Trends Plant Sci."},{"key":"2026090414222912900_kiag558-B22","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1105\/tpc.17.00579","article-title":"Defended to the nines: 25 years of resistance gene cloning identifies nine mechanisms for R protein function","volume":"30","author":"Kourelis","year":"2018","journal-title":"Plant Cell"},{"key":"2026090414222912900_kiag558-B23","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1038\/s41467-020-15601-5","article-title":"Regulation of reactive oxygen species during plant immunity through phosphorylation and ubiquitination of RBOHD","volume":"11","author":"Lee","year":"2020","journal-title":"Nat Commun."},{"key":"2026090414222912900_kiag558-B24","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1104\/pp.16.00992","article-title":"Capping protein modulates actin remodeling in response to reactive oxygen Species during plant innate immunity","volume":"173","author":"Li","year":"2017","journal-title":"Plant Physiol"},{"key":"2026090414222912900_kiag558-B25","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.chom.2014.02.009","article-title":"The FLS2-associated kinase BIK1 directly phosphorylates the NADPH oxidase RbohD to control plant immunity","volume":"15","author":"Li","year":"2014","journal-title":"Cell Host Microbe."},{"key":"2026090414222912900_kiag558-B26","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1016\/j.molp.2021.06.010","article-title":"The receptor-like cytoplasmic kinase RIPK regulates broad-spectrum ROS signaling in multiple layers of plant immune system","volume":"14","author":"Li","year":"2021","journal-title":"Mol Plant"},{"key":"2026090414222912900_kiag558-B27","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/s41586-022-04395-9","article-title":"Genome-edited powdery mildew resistance in wheat without growth penalties","volume":"602","author":"Li","year":"2022","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B28","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.molp.2025.01.016","article-title":"A genomic variation map provides insights into potato evolution and key agronomic traits","volume":"18","author":"Lian","year":"2025","journal-title":"Mol Plant."},{"key":"2026090414222912900_kiag558-B29","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1093\/plcell\/koab261","article-title":"Membrane nanodomains modulate formin condensation for actin remodeling in Arabidopsis innate immune responses","volume":"34","author":"Ma","year":"2022","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B30","doi-asserted-by":"publisher","first-page":"19613","DOI":"10.1073\/pnas.0705147104","article-title":"CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis","volume":"104","author":"Miya","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026090414222912900_kiag558-B31","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/s41586-021-03315-7","article-title":"Mutual potentiation of plant immunity by cell-surface and intracellular receptors","volume":"592","author":"Ngou","year":"2021","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B32","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1093\/plcell\/koac041","article-title":"Thirty years of resistance: zig-zag through the plant immune system","volume":"34","author":"Ngou","year":"2022","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B33","doi-asserted-by":"publisher","first-page":"8885","DOI":"10.1074\/jbc.M708106200","article-title":"Synergistic activation of the Arabidopsis NADPH oxidase AtrbohD by Ca2+ and phosphorylation","volume":"283","author":"Ogasawara","year":"2008","journal-title":"J Biol Chem"},{"key":"2026090414222912900_kiag558-B34","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1038\/s41587-019-0267-z","article-title":"Broad-spectrum resistance to bacterial blight in rice using genome editing","volume":"37","author":"Oliva","year":"2019","journal-title":"Nat Biotechnol"},{"key":"2026090414222912900_kiag558-B35","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s00425-022-03910-6","article-title":"Late blight resistance genes in potato breeding","volume":"255","author":"Paluchowska","year":"2022","journal-title":"Planta"},{"key":"2026090414222912900_kiag558-B36","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1038\/s41586-021-03829-0","article-title":"The EDS1\u2013PAD4\u2013ADR1 node mediates Arabidopsis pattern-triggered immunity","volume":"598","author":"Pruitt","year":"2021","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B37","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1096\/fj.08-114553","article-title":"Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox\/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox","volume":"23","author":"Raad","year":"2009","journal-title":"FASEB J"},{"key":"2026090414222912900_kiag558-B38","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1038\/s41586-023-06205-2","article-title":"Genome editing of a rice CDP-DAG synthase confers multipathogen resistance","volume":"618","author":"Sha","year":"2023","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B39","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1111\/pbi.12804","article-title":"Transfer of tomato immune receptor Ve1 confers Ave1-dependent Verticillium resistance in tobacco and cotton","volume":"16","author":"Song","year":"2018","journal-title":"Plant Biotechnol J"},{"key":"2026090414222912900_kiag558-B40","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1105\/tpc.110.082602","article-title":"Of PAMPs and effectors: the blurred PTI-ETI dichotomy","volume":"23","author":"Thomma","year":"2011","journal-title":"Plant Cell."},{"key":"2026090414222912900_kiag558-B41","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1038\/s41586-020-2702-1","article-title":"The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity","volume":"585","author":"Thor","year":"2020","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B42","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1038\/s41586-021-03987-1","article-title":"Activation of TIR signalling boosts pattern-triggered immunity","volume":"598","author":"Tian","year":"2021","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B43","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/s41586-019-1413-y","article-title":"A calmodulin-gated calcium channel links pathogen patterns to plant immunity","volume":"572","author":"Tian","year":"2019","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B44","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1073\/pnas.012452499","article-title":"Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response","volume":"99","author":"Torres","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026090414222912900_kiag558-B45","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1126\/science.adg5261","article-title":"Functional diversification of a wild potato immune receptor at its center of origin","volume":"381","author":"Torres Ascurra","year":"2023","journal-title":"Science"},{"key":"2026090414222912900_kiag558-B46","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1146\/annurev-phyto-102313-045854","article-title":"Susceptibility genes 101: how to be a good host","volume":"52","author":"van Schie","year":"2014","journal-title":"Annu Rev Phytopathol."},{"key":"2026090414222912900_kiag558-B47","doi-asserted-by":"publisher","first-page":"eaar4509","DOI":"10.1126\/sciadv.aar4509","article-title":"Pipecolic acid confers systemic immunity by regulating free radicals","volume":"4","author":"Wang","year":"2018","journal-title":"Sci Adv"},{"key":"2026090414222912900_kiag558-B48","doi-asserted-by":"publisher","first-page":"2961","DOI":"10.1016\/j.cell.2022.06.027","article-title":"Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi","volume":"185","author":"Wang","year":"2022","journal-title":"Cell"},{"key":"2026090414222912900_kiag558-B49","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/nbt.2969","article-title":"Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew","volume":"32","author":"Wang","year":"2014","journal-title":"Nat Biotechnol."},{"key":"2026090414222912900_kiag558-B50","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/nbt.3540","article-title":"Accelerated cloning of a potato late blight-resistance gene using RenSeq and SMRT sequencing","volume":"34","author":"Witek","year":"2016","journal-title":"Nat Biotechnol"},{"key":"2026090414222912900_kiag558-B51","doi-asserted-by":"publisher","first-page":"3840","DOI":"10.1016\/j.molcel.2025.09.010","article-title":"Orchestration of plant PRR- and NLR-mediated immunity: protein kinases and beyond","volume":"85","author":"Yan","year":"2025","journal-title":"Mol Cell."},{"key":"2026090414222912900_kiag558-B52","doi-asserted-by":"publisher","DOI":"10.1111\/pbi.70331","article-title":"Winning by losing: exploiting modified plant susceptibility genes to counteract necrotrophic fungal pathogens","volume":"23:5710\u20135727.","author":"You","year":"2025","journal-title":"Plant Biotechnol J."},{"key":"2026090414222912900_kiag558-B56","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1111\/pbi.14332","article-title":"PTI-ETI synergistic signal mechanisms in plant immunity","volume":"22","author":"Yu","year":"2024","journal-title":"Plant Biotechnol J."},{"key":"2026090414222912900_kiag558-B53","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/s41586-021-03316-6","article-title":"Pattern-recognition receptors are required for NLR-mediated plant immunity","volume":"592","author":"Yuan","year":"2021","journal-title":"Nature"},{"key":"2026090414222912900_kiag558-B54","doi-asserted-by":"publisher","first-page":"102030","DOI":"10.1016\/j.pbi.2021.102030","article-title":"PTI-ETI crosstalk: an integrative view of plant immunity","volume":"62","author":"Yuan","year":"2021","journal-title":"Curr Opin Plant Biol."},{"key":"2026090414222912900_kiag558-B55","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.chom.2018.08.007","article-title":"The MAP4 kinase SIK1 ensures robust extracellular ROS burst and antibacterial immunity in plants","volume":"24","author":"Zhang","year":"2018","journal-title":"Cell Host Microbe"}],"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/202\/1\/kiag558\/70964720\/kiag558.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/202\/1\/kiag558\/70964720\/kiag558.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:22:42Z","timestamp":1788546162000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/article\/doi\/10.1093\/plphys\/kiag558\/8785947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":56,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/plphys\/kiag558","relation":{},"ISSN":["0032-0889","1532-2548"],"issn-type":[{"value":"0032-0889","type":"print"},{"value":"1532-2548","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,9,1]]},"article-number":"kiag558"}}