{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:08:42Z","timestamp":1792786122417,"version":"4.5.0"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Hainan Provincial Natural Science Foundation of China","award":["326YXQN0953"],"award-info":[{"award-number":["326YXQN0953"]}]},{"name":"International Science and Technology Cooperation Program of Hainan Province","award":["GHYF2026030"],"award-info":[{"award-number":["GHYF2026030"]}],"id":[{"id":"https:\/\/ror.org\/00bsdxt65","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Hainan Province Science and Technology Special Fund","award":["ZDYF2026XDNY164"],"award-info":[{"award-number":["ZDYF2026XDNY164"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Light regulates carotenoid biosynthesis in plants at multiple levels. However, the involvement of protein phosphorylation in light-induced carotenoid biosynthesis remains largely unexplored. Our previous studies demonstrated that blue light promotes carotenoid biosynthesis in mango fruit. In this study, we elucidated that blue light induces carotenoid biosynthesis in mango fruit by disrupting the MiMPK4 (MITOGEN-ACTIVATED PROTEIN KINASE 4)-MiRAP2.11 regulatory module. MiRAP2.11, an ethylene response factor subfamily transcription factor (TF) induced by blue light, acts as a nucleus-localized transcriptional activator. MiRAP2.11 activates the expression of carotenoid biosynthesis-related gene MiZEP (zeaxanthin epoxidase) by directly binding to its promoter, leading to carotenoid biosynthesis in mango fruit. Conversely, MiMPK4 negatively responds to blue light, interacts with MiRAP2.11 and phosphorylates it, promoting proteasome-dependent degradation of MiRAP2.11. Furthermore, the protein interaction between MiMPK4 and MiRAP2.11, rather than phosphorylation, reduces the binding activity of MiRAP2.11 to the MiZEP promoter, thereby weakening its transcriptional activation of MiZEP. Therefore, MiMPK4 suppresses MiRAP2.11-induced carotenoid biosynthesis through a dual inhibitory mechanism: phosphorylation-triggered protein degradation and interaction-mediated suppression of its transcriptional activation. Collectively, these findings demonstrate that blue light induces carotenoid biosynthesis in mango fruit flesh by disrupting the MiMPK4\u2013MiRAP2.11 signaling module. This study provides new insights into the role of phosphorylation in light-induced carotenoid biosynthesis, further enriching the molecular network of blue light regulation of carotenoid biosynthesis pathways.<\/jats:p>","DOI":"10.1093\/plphys\/kiag672","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T08:45:09Z","timestamp":1788770709000},"source":"Crossref","is-referenced-by-count":0,"title":["Dual disruption of MiMPK4-mediated phosphorylation and interaction with MiRAP2.11 is required for blue light-induced carotenoid biosynthesis in mango fruit"],"prefix":"10.1093","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4548-8751","authenticated-orcid":false,"given":"Manman","family":"Zhang","sequence":"first","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]},{"name":"Zhejiang University (Hainan) Advanced Technology and Industrial Innovation Platform, Hainan Institute of Zhejiang University , Zhenzhou Road, Science and Technology City, Yazhou District, Sanya 572025, Hainan ,","place":["China"]},{"name":"Frontiers Science Center for Molecular Design Breeding (MOE), Beijing Key Laboratory of Development and Quality Control of Ornamental Crops, Department of Ornamental Horticulture, College of Horticulture, China Agricultural University , No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]},{"name":"Zhejiang University (Hainan) Advanced Technology and Industrial Innovation Platform, Hainan Institute of Zhejiang University , Zhenzhou Road, Science and Technology City, Yazhou District, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Yu","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1007-1879","authenticated-orcid":false,"given":"Yongchen","family":"Fang","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Jin","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]},{"name":"Zhejiang University (Hainan) Advanced Technology and Industrial Innovation Platform, Hainan Institute of Zhejiang University , Zhenzhou Road, Science and Technology City, Yazhou District, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5110-0026","authenticated-orcid":false,"given":"Chen","family":"Pan","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahao","family":"Wu","sequence":"additional","affiliation":[{"name":"Agricultural Experiment Station, Zhejiang University , Si'an Town, Changxing County, Huzhou 313113, Zhejiang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5736-8121","authenticated-orcid":false,"given":"Chengkun","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University , Huijin Road, Yazhou Distrcit, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4854-3982","authenticated-orcid":false,"given":"Minjie","family":"Qian","sequence":"additional","affiliation":[{"name":"School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University , Huijin Road, Yazhou Distrcit, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3315-8835","authenticated-orcid":false,"given":"\u00c5ke","family":"Strid","sequence":"additional","affiliation":[{"name":"School of Science and Technology, \u0150rebro University , Fakultetsgatan 1, \u0150rebro SE-701 82 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7421-7240","authenticated-orcid":false,"given":"Kaibing","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University , Huijin Road, Yazhou Distrcit, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8103-3095","authenticated-orcid":false,"given":"Songling","family":"Bai","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8033-5094","authenticated-orcid":false,"given":"Junbei","family":"Ni","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]},{"name":"Zhejiang University (Hainan) Advanced Technology and Industrial Innovation Platform, Hainan Institute of Zhejiang University , Zhenzhou Road, Science and Technology City, Yazhou District, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8656-9035","authenticated-orcid":false,"given":"Yuanwen","family":"Teng","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Horticultural Crop Quality Improvement, College of Agriculture and Biotechnology, Zhejiang University , No. 866, Yuhangtang Road, Xihu District, Hangzhou 310058, Zhejiang ,","place":["China"]},{"name":"Zhejiang University (Hainan) Advanced Technology and Industrial Innovation Platform, Hainan Institute of Zhejiang University , Zhenzhou Road, Science and Technology City, Yazhou District, Sanya 572025, Hainan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"2026092106114862700_kiag672-B1","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1111\/tpj.14510","article-title":"Two B-box proteins, PpBBX18 and PpBBX21, antagonistically regulate anthocyanin biosynthesis via competitive association with Pyrus pyrifolia ELONGATED HYPOCOTYL 5 in the peel of pear fruit","volume":"100","author":"Bai","year":"2019","journal-title":"Plant J."},{"key":"2026092106114862700_kiag672-B2","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1016\/j.hpj.2022.09.015","article-title":"Phytoene synthases 1 modulates tomato fruit quality through influencing the metabolic flux between carotenoid and flavonoid pathways","volume":"10","author":"Cao","year":"2024","journal-title":"Horticult Plant J"},{"key":"2026092106114862700_kiag672-B3","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1016\/j.molp.2020.06.009","article-title":"TBtools: an integrative toolkit developed for interactive analyses of big biological data","volume":"13","author":"Chen","year":"2020","journal-title":"Mol Plant."},{"key":"2026092106114862700_kiag672-B4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2405894122","article-title":"Ethylene response factor SlERF.D6 promotes ripening in part through transcription factors SlDEAR2 and SlTCP12","volume":"122","author":"Chen","year":"2025","journal-title":"Proc Natl Acad Sci U S A."},{"key":"2026092106114862700_kiag672-B5","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1093\/plcell\/koac025","article-title":"SlERF.F12 modulates the transition to ripening in tomato fruit by recruiting the co-repressor TOPLESS and histone deacetylases to repress key ripening genes","volume":"34","author":"Deng","year":"2022","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B6","doi-asserted-by":"publisher","first-page":"7405","DOI":"10.1021\/jf070711h","article-title":"Carotenoid biosynthetic pathway in the citrus genus: number of copies and phylogenetic diversity of seven genes","volume":"55","author":"Fanciullino","year":"2007","journal-title":"J Agric Food Chem."},{"key":"2026092106114862700_kiag672-B7","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1104\/pp.111.173369","article-title":"Lutein from deepoxidation of lutein epoxide replaces zeaxanthin to sustain an enhanced capacity for nonphotochemical chlorophyll fluorescence quenching in avocado shade leaves in the dark","volume":"156","author":"Foerster","year":"2011","journal-title":"Plant Physiol."},{"key":"2026092106114862700_kiag672-B8","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.plipres.2003.10.002","article-title":"The biosynthesis and nutritional uses of carotenoids","volume":"43","author":"Fraser","year":"2004","journal-title":"Prog Lipid Res."},{"key":"2026092106114862700_kiag672-B9","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1105\/tpc.12.3.393","article-title":"Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression","volume":"12","author":"Fujimoto","year":"2000","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B10","doi-asserted-by":"publisher","first-page":"6274","DOI":"10.1093\/jxb\/erab283","article-title":"Red light-induced kumquat fruit coloration is attributable to increased carotenoid metabolism regulated by FcrNAC22","volume":"72","author":"Gong","year":"2021","journal-title":"J Exp Bot"},{"key":"2026092106114862700_kiag672-B11","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.scienta.2009.01.031","article-title":"Effects of fruit bagging on coloring and related physiology, and qualities of red Chinese sand pears during fruit maturation","volume":"121","author":"Huang","year":"2009","journal-title":"Sci Horticult"},{"key":"2026092106114862700_kiag672-B12","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1186\/s12870-016-0785-5","article-title":"Carotenoid metabolism during bilberry (Vaccinium myrtillus L.) fruit development under different light conditions is regulated by biosynthesis and degradation","volume":"16","author":"Karppinen","year":"2016","journal-title":"BMC Plant Biol"},{"key":"2026092106114862700_kiag672-B13","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1126\/science.284.5416.977","article-title":"Roles of phosphorylation sites in regulating activity of the transcription factor Pho4","volume":"284","author":"Komeili","year":"1999","journal-title":"Science (New York, N.Y.)"},{"key":"2026092106114862700_kiag672-B14","doi-asserted-by":"publisher","first-page":"87","DOI":"10.5511\/plantbiotechnology.18.0122b","article-title":"The function of ETHYLENE RESPONSE FACTOR genes in the light-induced anthocyanin production of Arabidopsis thaliana leaves","volume":"35","author":"Koyama","year":"2018","journal-title":"Plant Biotechnol (Tokyo, Japan)"},{"key":"2026092106114862700_kiag672-B15","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-016-0731-6","article-title":"Substrate thiophosphorylation by Arabidopsis mitogen-activated protein kinases","volume":"16","author":"Leissing","year":"2016","journal-title":"BMC Plant Biol."},{"key":"2026092106114862700_kiag672-B16","doi-asserted-by":"publisher","first-page":"W293","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"2026092106114862700_kiag672-B17","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29315-3","article-title":"The phytochrome interacting proteins ERF55 and ERF58 repress light-induced seed germination in Arabidopsis thaliana","volume":"13","author":"Li","year":"2022","journal-title":"Nat Commun."},{"key":"2026092106114862700_kiag672-B18","doi-asserted-by":"publisher","DOI":"10.3390\/horticulturae10030239","article-title":"Identification of eggplant SmMPK gene family and functional verification of SmMPK4.1","volume":"10","author":"Liao","year":"2024","journal-title":"Horticulturae"},{"key":"2026092106114862700_kiag672-B19","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/nph.12771","article-title":"The chimeric repressor version of an ethylene response factor (ERF) family member, sl-ERF.B3, shows contrasting effects on tomato fruit ripening","volume":"203","author":"Liu","year":"2014","journal-title":"New Phytol."},{"key":"2026092106114862700_kiag672-B20","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.1111\/pce.14606","article-title":"Revisiting the role of MAPK signalling pathway in plants and its manipulation for crop improvement","volume":"46","author":"Manna","year":"2023","journal-title":"Plant Cell Environ."},{"key":"2026092106114862700_kiag672-B21","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1093\/plcell\/koac006","article-title":"Low temperature inhibits anthocyanin accumulation in strawberry fruit by activating FvMAPK3-induced phosphorylation of FvMYB10 and degradation of Chalcone Synthase 1","volume":"34","author":"Mao","year":"2022","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B22","doi-asserted-by":"publisher","first-page":"16021","DOI":"10.1021\/acs.jafc.2c07137","article-title":"Blue light simultaneously induces peel anthocyanin biosynthesis and flesh carotenoid\/sucrose biosynthesis in mango fruit","volume":"70","author":"Ni","year":"2022","journal-title":"J Agric Food Chem."},{"key":"2026092106114862700_kiag672-B23","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1093\/plcell\/koad077","article-title":"The ethylene-responsive transcription factor PpERF9 represses PpRAP2.4 and PpMYB114 via histone deacetylation to inhibit anthocyanin biosynthesis in pear","volume":"35","author":"Ni","year":"2023","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B24","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.molp.2014.12.007","article-title":"Carotenoid metabolism in plants","volume":"8","author":"Nisar","year":"2015","journal-title":"Mol Plant."},{"key":"2026092106114862700_kiag672-B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2024.109315","article-title":"Blue light-induced MiBBX24 and MiBBX27 simultaneously promote peel anthocyanin and flesh carotenoid biosynthesis in mango","volume":"219","author":"Pan","year":"2025","journal-title":"Plant Physiol Biochem."},{"key":"2026092106114862700_kiag672-B26","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1101\/gad.1740009","article-title":"MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays","volume":"23","author":"Popescu","year":"2009","journal-title":"Genes Dev."},{"key":"2026092106114862700_kiag672-B27","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1111\/febs.13159","article-title":"MicroRNA biogenesis factor DRB1 is a phosphorylation target of mitogen activated protein kinase MPK3 in both rice and Arabidopsis","volume":"282","author":"Raghuram","year":"2015","journal-title":"FEBS J."},{"key":"2026092106114862700_kiag672-B28","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.abb.2010.06.016","article-title":"Supply of precursors for carotenoid biosynthesis in plants","volume":"504","author":"Rodriguez-Concepcion","year":"2010","journal-title":"Arch Biochem Biophys."},{"key":"2026092106114862700_kiag672-B29","doi-asserted-by":"publisher","first-page":"3343","DOI":"10.1105\/tpc.114.128702","article-title":"A mitogen-activated protein kinase cascade module, MKK3-MPK6 and MYC2, is involved in blue light-mediated seedling development in Arabidopsis","volume":"26","author":"Sethi","year":"2014","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B30","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01884","article-title":"The role and regulation of ABI5 (ABA-Insensitive 5) in plant development, abiotic stress responses and phytohormone crosstalk","volume":"7","author":"Skubacz","year":"2016","journal-title":"Front Plant Sci."},{"key":"2026092106114862700_kiag672-B31","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.01017","article-title":"Transcriptional regulation of carotenoid biosynthesis in plants: so many regulators, so little consensus","volume":"10","author":"Stanley","year":"2019","journal-title":"Front Plant Sci."},{"key":"2026092106114862700_kiag672-B32","doi-asserted-by":"publisher","first-page":"R338","DOI":"10.1016\/j.cub.2011.02.036","article-title":"The molecular mechanism and evolution of the GA-GID1-DELLA signaling module in plants","volume":"21","author":"Sun","year":"2011","journal-title":"Curr Biol."},{"key":"2026092106114862700_kiag672-B33","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.molp.2017.09.010","article-title":"Carotenoid metabolism in plants: the role of plastids","volume":"11","author":"Sun","year":"2018","journal-title":"Mol Plant."},{"key":"2026092106114862700_kiag672-B34","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1105\/tpc.106.046581","article-title":"The mitogen-activated protein kinase cascade MKK3-MPK6 is an important part of the jasmonate signal transduction pathway in Arabidopsis","volume":"19","author":"Takahashi","year":"2007","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B35","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13875-y","article-title":"MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response","volume":"11","author":"Takahashi","year":"2020","journal-title":"Nat Commun."},{"key":"2026092106114862700_kiag672-B36","doi-asserted-by":"publisher","first-page":"11626","DOI":"10.1073\/pnas.0914428107","article-title":"Direct regulation of phytoene synthase gene expression and carotenoid biosynthesis by phytochrome-interacting factors","volume":"107","author":"Toledo-Ortiz","year":"2010","journal-title":"Proc Natl Acad Sci U S A."},{"key":"2026092106114862700_kiag672-B37","doi-asserted-by":"publisher","first-page":"4535","DOI":"10.1093\/plcell\/koae223","article-title":"MPK4-mediated phosphorylation of PHYTOCHROME INTERACTING FACTOR4 controls thermosensing by regulating histone variant H2A.Z deposition","volume":"36","author":"Verma","year":"2024","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B38","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhaf054","article-title":"Carotene hydroxylase DcCYP97A3 affects carotenoid metabolic flow and taproot color by influencing the conversion of \u03b1-carotene to lutein in carrot","volume":"12","author":"Wang","year":"2025","journal-title":"Hortic Res."},{"key":"2026092106114862700_kiag672-B39","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1093\/plcell\/koac049","article-title":"Phosphorylation of MdERF17 by MdMPK4 promotes apple fruit peel degreening during light\/dark transitions","volume":"34","author":"Wang","year":"2022","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B40","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s00425-019-03157-8","article-title":"Overexpression of a basic helix-loop-helix transcription factor gene, SlbHLH22, promotes early flowering and accelerates fruit ripening in tomato (Solanum lycopersicum L.)","volume":"250","author":"Waseem","year":"2019","journal-title":"Planta"},{"key":"2026092106114862700_kiag672-B41","doi-asserted-by":"publisher","first-page":"2887","DOI":"10.1093\/plcell\/koad122","article-title":"Ethylene enhances MdMAPK3-mediated phosphorylation of MdNAC72 to promote apple fruit softening","volume":"35","author":"Wei","year":"2023","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B42","doi-asserted-by":"publisher","first-page":"29476","DOI":"10.1074\/jbc.274.41.29476","article-title":"Phosphorylation of the parsley bZIP transcription factor CPRF2 is regulated by light","volume":"274","author":"Wellmer","year":"1999","journal-title":"J Biol Chem."},{"key":"2026092106114862700_kiag672-B43","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1104\/pp.107.104828","article-title":"Transcription factor RAP2.2 and its interacting partner SINAT2: stable elements in the carotenogenesis of Arabidopsis leaves","volume":"145","author":"Welsch","year":"2007","journal-title":"Plant Physiol."},{"key":"2026092106114862700_kiag672-B44","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24108829","article-title":"Genome-wide identification of the MAPK and MAPKK gene families in response to cold stress in Prunus mume","volume":"24","author":"Wen","year":"2023","journal-title":"Int J Mol Sci."},{"key":"2026092106114862700_kiag672-B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112832","article-title":"Banana MKK1 modulates fruit ripening via the MKK1-MPK6-3\/11-4-bZIP21 module","volume":"42","author":"Wu","year":"2023","journal-title":"Cell Rep."},{"key":"2026092106114862700_kiag672-B46","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koaf032","article-title":"The maize GSK3-like kinase ZmSK1 negatively regulates drought tolerance by phosphorylating the transcription factor ZmCPP2","volume":"37","author":"Xiang","year":"2025","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B47","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/pbi.13941","article-title":"MPK6-mediated HY5 phosphorylation regulates light-induced anthocyanin accumulation in apple fruit","volume":"21","author":"Xing","year":"2023","journal-title":"Plant Biotechnol J."},{"key":"2026092106114862700_kiag672-B48","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1016\/j.hpj.2023.02.010","article-title":"New insights into the carotenoid biosynthesis in Torreya grandis kernels","volume":"9","author":"Yan","year":"2023","journal-title":"Horticult Plant J"},{"key":"2026092106114862700_kiag672-B49","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1111\/tpj.15267","article-title":"Apple MPK4 mediates phosphorylation of MYB1 to enhance light-induced anthocyanin accumulation","volume":"106","author":"Yang","year":"2021","journal-title":"Plant J."},{"key":"2026092106114862700_kiag672-B50","doi-asserted-by":"publisher","DOI":"10.1038\/hortres.2015.36","article-title":"Carotenoid metabolism and regulation in horticultural crops","volume":"2","author":"Yuan","year":"2015","journal-title":"Hortic Res."},{"key":"2026092106114862700_kiag672-B51","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1093\/plcell\/koac363","article-title":"Jasmonate activates a CsMPK6-CsMYC2 module that regulates the expression of \u03b2-citraurin biosynthetic genes and fruit coloration in orange (Citrus sinensis)","volume":"35","author":"Yue","year":"2023","journal-title":"Plant Cell."},{"key":"2026092106114862700_kiag672-B52","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.1111\/pbi.70100","article-title":"CRY1\u2013GAIP1 complex mediates blue light to hinder the repression of PIF5 on AGL5 to promote carotenoid biosynthesis in mango fruit","volume":"23","author":"Zhang","year":"2025","journal-title":"Plant Biotechnol J."},{"key":"2026092106114862700_kiag672-B53","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1111\/jipb.13913","article-title":"Switch on and off: phospho-events in light signaling pathways","volume":"67","author":"Zhang","year":"2025","journal-title":"J Integr Plant Biol."},{"key":"2026092106114862700_kiag672-B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112729","article-title":"Protein phosphorylation: a molecular switch in plant signaling","volume":"42","author":"Zhang","year":"2023","journal-title":"Cell Rep."},{"key":"2026092106114862700_kiag672-B55","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiae574","article-title":"Chemical-sensitized MITOGEN-ACTIVATED PROTEIN KINASE 4 provides insights into its functions in plant growth and immunity","volume":"197","author":"Zhang","year":"2024","journal-title":"Plant Physiol."},{"key":"2026092106114862700_kiag672-B56","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232315225","article-title":"Genome-wide identification of AP2\/ERF superfamily genes in Juglans mandshurica and expression analysis under cold stress","volume":"23","author":"Zhao","year":"2022","journal-title":"Int J Mol Sci."},{"key":"2026092106114862700_kiag672-B57","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.hpj.2020.05.004","article-title":"Overexpression of the watermelon ethylene response factor ClERF069 in transgenic tomato resulted in delayed fruit ripening","volume":"6","author":"Zhou","year":"2020","journal-title":"Horticult Plant J"},{"key":"2026092106114862700_kiag672-B58","doi-asserted-by":"publisher","first-page":"3137","DOI":"10.1093\/jxb\/erab047","article-title":"Ethylene activation of carotenoid biosynthesis by a novel transcription factor CsERF061","volume":"72","author":"Zhu","year":"2021","journal-title":"J Exp Bot."}],"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article-pdf\/doi\/10.1093\/plphys\/kiag672\/70976023\/kiag672.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/202\/1\/kiag672\/70976023\/kiag672.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/article-pdf\/202\/1\/kiag672\/70976023\/kiag672.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:47:36Z","timestamp":1789991256000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/article\/doi\/10.1093\/plphys\/kiag672\/8786546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/plphys\/kiag672","relation":{},"ISSN":["0032-0889","1532-2548"],"issn-type":[{"value":"0032-0889","type":"print"},{"value":"1532-2548","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,9,1]]},"article-number":"kiag672"}}