{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:55:37Z","timestamp":1791284137738,"version":"4.1.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Brown planthopper (Nilaparvata lugens, BPH) is a major pest that severely limits rice production. Although plant defense against BPH involves complex metabolic and structural responses, the role of non-protein amino acids (NPAAs) in this process remains poorly understood. Here, we demonstrate that (R)-\u03b2-tyrosine functions as a key defense metabolite that enhances rice resistance to BPH. Exogenous application and genetic manipulation across different rice backgrounds revealed that (R)-\u03b2-tyrosine does not directly affect insect survival but instead acts through host-mediated mechanisms. Transcriptomic, histological, and physiological analyses showed that (R)-\u03b2-tyrosine promotes the expression of phenylpropanoid pathway genes, leading to increased lignin accumulation, enhanced mechanical strength, and reinforced physical barriers that restrict BPH feeding. Mechanistically, we identify the JA-inducible transcription factor OsMYB72 as a key activator of OsTAM1, the enzyme catalyzing \u03b2-tyrosine biosynthesis, thereby linking JA signaling to (R)-\u03b2-tyrosine accumulation. This JA-OsMYB72-OsTAM1 module coordinates \u03b2-tyrosine production with downstream phenylpropanoid metabolism, promoting lignin deposition and reinforcing structural defense against BPH. Together, our findings establish a link between NPAA metabolism and lignin-associated structural defense, offering insight into metabolite mediated plant resistance to piercing-sucking herbivores.<\/jats:p>","DOI":"10.1093\/plphys\/kiag743","type":"journal-article","created":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:40:37Z","timestamp":1791027637000},"source":"Crossref","is-referenced-by-count":0,"title":["A JA-OsMYB72-OsTAM1 module promotes (R)-\u03b2-tyrosine-mediated lignin defense against brown planthopper in rice"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4536-1112","authenticated-orcid":false,"given":"Mengyun","family":"Xu","sequence":"first","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genxiang","family":"Bai","sequence":"additional","affiliation":[{"name":"Hubei Shizhen Laboratory, School of Basic Medical Sciences, Hubei University of Chinese Medicine , Wuhan 430065 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junru","family":"Long","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2676-7364","authenticated-orcid":false,"given":"Dongqian","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9161-8735","authenticated-orcid":false,"given":"Ping","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zepeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Tobacco Shaoguan Co. Ltd. , Shaoguan, Guangdong 512000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6172-7153","authenticated-orcid":false,"given":"Zhongyan","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayun","family":"Hu","sequence":"additional","affiliation":[{"name":"Guangzhou Suicong Agriculture and Forestry Development Co., Ltd. , Guangzhou 510000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3643-7875","authenticated-orcid":false,"given":"Shaoqun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences , Shenzhen 518120 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8215-8084","authenticated-orcid":false,"given":"Jian","family":"Yan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Environment in the Tropics, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Eco-Circular Agriculture; Guangdong Engineering Research Centre for Modern Eco-Agriculture; College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,6]]},"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article-pdf\/doi\/10.1093\/plphys\/kiag743\/71625196\/kiag743.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article-pdf\/doi\/10.1093\/plphys\/kiag743\/71625196\/kiag743.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:38:28Z","timestamp":1791283108000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/advance-article\/doi\/10.1093\/plphys\/kiag743\/8868857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/plphys\/kiag743","relation":{},"ISSN":["0032-0889","1532-2548"],"issn-type":[{"value":"0032-0889","type":"print"},{"value":"1532-2548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,6]]},"article-number":"kiag743"}}