{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T14:44:54Z","timestamp":1782485094000,"version":"3.54.5"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T00:00:00Z","timestamp":1626307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neurovascular compression (NVC) in patients with trigeminal neuralgia (TN) can be a factor of treatment outcome, especially in microvascular decompression and stereotactic radiosurgery. No such effect has been reported in percutaneous radiofrequency rhizotomy (RF). This study aims to investigate whether NVC affects the efficacy of RF in patients with TN.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We retrospectively reviewed patients with TN who received RF in our institution. Pretreatment magnetic resonance imaging was performed in every patient, and the presence of NVC was reviewed independently by two physicians. The patients were followed up at least for a year after the treatment. Pain severity was assessed with a numeric rating scale (NRS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Sixty-two patients were included in the study. All of the patients had single-sided lesions, and 35 patients had NVC. There were no significant differences between these two groups of patients in terms of gender distribution, age, and pretreatment pain severity. Comparable pain severity improvement was found at 1-year follow-up between these two groups (NRS 7.93\u2009\u00b1\u20090.492 without compression vs 7.57\u2009\u00b1\u20090.451 with compression, P\u2009=\u20090.600). No significant difference in posttreatment pain severity at 1 year was found between these two patient groups (NRS 1.37\u2009\u00b1\u20090.466 without compression vs 1.66\u2009\u00b1\u20090.458 with compression, P\u2009=\u20090.667).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>For patients with TN treated by RF, the presence or absence of NVC is not likely to affect the 1-year pain control rate.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/pm\/pnab221","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T19:11:43Z","timestamp":1626203503000},"page":"807-814","source":"Crossref","is-referenced-by-count":6,"title":["Percutaneous Radiofrequency Rhizotomy Is Equally Effective for Trigeminal Neuralgia Patients with or Without Neurovascular Compression"],"prefix":"10.1093","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8416-8817","authenticated-orcid":false,"given":"Chih-Hao","family":"Kao","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hsueh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jen-Tsung","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi, Taiwan"},{"name":"College of Medicine, Chang Gung University, Tao-Yuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Hsiung","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chia-Yi, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Hsiu-Chu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,15]]},"reference":[{"issue":"suppl 1","key":"2022040813455976900_pnab221-B1","first-page":"25","article-title":"A review of percutaneous treatments for trigeminal neuralgia","volume":"10","author":"Cheng","year":"2014","journal-title":"Neurosurgery"},{"issue":"15","key":"2022040813455976900_pnab221-B2","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1212\/01.wnl.0000326598.83183.04","article-title":"Practice parameter: The diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies","volume":"71","author":"Gronseth","year":"2008","journal-title":"Neurology"},{"key":"2022040813455976900_pnab221-B3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2147\/TCRM.S37592","article-title":"Advances in diagnosis and treatment of trigeminal neuralgia","volume":"11","author":"Montano","year":"2015","journal-title":"Ther Clin Risk Manag"},{"issue":"1","key":"2022040813455976900_pnab221-B4","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00002508-200201000-00002","article-title":"Pathophysiology of trigeminal neuralgia: the ignition hypothesis","volume":"18","author":"Devor","year":"2002","journal-title":"Clin J Pain"},{"issue":"1","key":"2022040813455976900_pnab221-B5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s701-002-8269-4","article-title":"Anatomical observations during microvascular decompression for idiopathic trigeminal neuralgia (with correlations between topography of pain and site of the neurovascular conflict). 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