{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:09:17Z","timestamp":1791176957496,"version":"4.1.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Trigeminal neuralgia is considered the worst pain a human being can experience. Initial treatment uses anticonvulsant sodium channel blockers, which relieve pain in approximately 70% of patients. In refractory cases, it is possible to perform ablative treatments, decompressive surgeries, and neuromodulatory techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This report describes the treatment of a patient with refractory trigeminal neuralgia who continued to have a painful clinical presentation after four surgical procedures and three ablative procedures. The patient presented with severe pain (verbal numerical scale between 9 and 10), manifesting an evident suicidal ideation. A dorsal root ganglion (DRG) stimulation electrode was implanted in the trigeminal ganglion through intraoral puncture with maxillary fixation of the electrode, in order to minimize the chances of displacement. The test phase consisted of implanting a quadripolar electrode for DRG stimulation through puncture lateral to the buccal rim in a fluoroscopic coaxial view. The electrode was fixed to the skin and maintained for 5\u00a0days, during which the patient remained completely pain\u00a0free. After the 5-day test period, the definitive stimulation electrode was implanted, this time with intraoral puncture and maxillary electrode fixation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patient remains pain free in the 3-month follow-up, with no displacement of the electrode.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The DRG electrode may be considered a therapeutic option in patients with severe trigeminal neuralgia. Controlled studies must be performed to determine the efficacy and safety of the method.<\/jats:p><\/jats:sec>","DOI":"10.1093\/pm\/pnac120","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T14:00:31Z","timestamp":1660744831000},"page":"300-305","source":"Crossref","is-referenced-by-count":2,"title":["New Trigeminal Stimulation Technique with Dorsal Root Ganglion Stimulation Electrode and Maxillary Fixation: Technique Description"],"prefix":"10.1093","volume":"24","author":[{"given":"Andr\u00e9 Marques","family":"Mansano","sequence":"first","affiliation":[{"name":"Interventional Pain Management, Hospital Israelita Albert Einstein , S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago","family":"Nouer Frederico","sequence":"additional","affiliation":[{"name":"Interventional Pain Management, Hospital Israelita Albert Einstein , S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Luiz","family":"de Mirando","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein , S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adonai Peixoto","family":"Cheim Junior","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein , S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"issue":"8","key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1056\/NEJMra1914484","article-title":"Trigeminal neuralgia","volume":"383","author":"Cruccu","year":"2020","journal-title":"N Engl J Med"},{"issue":"6","key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/ene.13950","article-title":"European Academy of Neurology guideline on trigeminal neuralgia","volume":"26","author":"Bendtsen","year":"2019","journal-title":"Eur J Neurol"},{"key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/978-3-7091-8592-6_37","volume-title":"Advances in Stereotactic and Functional Neurosurgery 4","author":"Meyerson","year":"1980"},{"issue":"2","key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1055\/s-0028-1090324","article-title":"Percutaneous electro stimulation of the trigeminal nerve in patients with atypical trigeminal neuralgia","volume":"21","author":"Steude","year":"1978","journal-title":"Minim Invasive Neurosurg"},{"issue":"2","key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3171\/jns.1997.86.2.0197","article-title":"Chronic electrical stimulation of the Gasserian ganglion for the relief of pain in a series of 34 patients","volume":"86","author":"Taub","year":"1997","journal-title":"J Neurosurg"},{"key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/978-3-211-33081-4_11","volume-title":"Operative Neuromodulation","author":"Mehrkens","year":"2007"},{"issue":"6","key":"2023030119154234700_","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/ner.13421","article-title":"Implantable peripheral nerve stimulation for trigeminal neuropathic pain: A systematic review and meta-analysis","volume":"24","author":"Ni","year":"2021","journal-title":"Neuromodulation"}],"container-title":["Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/painmedicine\/advance-article-pdf\/doi\/10.1093\/pm\/pnac120\/46500312\/pnac120.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/painmedicine\/article-pdf\/24\/3\/300\/49346104\/pnac120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/painmedicine\/article-pdf\/24\/3\/300\/49346104\/pnac120.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T21:47:54Z","timestamp":1700948874000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/painmedicine\/article\/24\/3\/300\/6670635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,17]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,8,17]]},"published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/pm\/pnac120","relation":{},"ISSN":["1526-2375","1526-4637"],"issn-type":[{"value":"1526-2375","type":"print"},{"value":"1526-4637","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3,1]]},"published":{"date-parts":[[2022,8,17]]}}}