{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T02:23:28Z","timestamp":1781144608937,"version":"3.54.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Centre for Research Excellence on Low Back Pain","award":["APP1171459"],"award-info":[{"award-number":["APP1171459"]}]},{"name":"New South Wales State Insurance Regulatory Authority"},{"name":"Australian Research Council Future","award":["FT19010218"],"award-info":[{"award-number":["FT19010218"]}]},{"DOI":"10.13039\/501100024339","name":"Monash Addiction Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024339","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Post-Doctoral Seeding"},{"DOI":"10.13039\/501100000925","name":"NHMRC","doi-asserted-by":"publisher","award":["GNT2025894"],"award-info":[{"award-number":["GNT2025894"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To identify longitudinal patterns in opioid dispensing dosages for workers with low back pain within a workers\u2019 compensation setting and to explore the risk factors associated with high-dose and persistent opioid use.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>We included workers with accepted claims for low back pain received by insurers between January 1, 2010, and June 30, 2016, with a follow-up period of 3.5\u2009years (data censoring on December 31, 2020) across Victoria. Trajectory modeling was used to identify different opioid dispensing patterns. Logistic regressions were utilized to compare the workers\u2019 characteristics across different opioid dispensing pattern groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among 14\u200a703 accepted claims, 33.1% reported receiving opioid medications as part of their claims. Six opioid dispensing patterns were identified. Individuals in the highest socioeconomic status (SES) quintile were less likely to rapidly escalate to dispensing high-dose opioids (odds ratio [OR]: 0.58, 99% CI 0.34, 0.99) compared to other quintiles. Workers dispensed gabapentinoids and antidepressants showed an increased risk of long-term high-dose opioid use (OR: 7.96, 99% CI 5.42, 11.69; OR: 21.75, 99% CI 14.30, 33.08) relative to workers with a single opioid dispensing. Those who had surgery were also more likely to use long-term high-dose opioids compared to a non-surgery group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Lower SES, having gabapentinoids or antidepressants prescriptions or having had surgery are all associated with persistent opioid use among workers with LBP. These demographic and clinical risk factors for developing persistent opioid use could help identify individuals who would benefit from early intervention, reducing the likelihood of opioid dependence for pain management and minimizing the risk of harm.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/pm\/pnaf017","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T21:19:42Z","timestamp":1741123182000},"page":"362-371","source":"Crossref","is-referenced-by-count":1,"title":["Longitudinal patterns of opioid dispensing dosages for compensated Australian workers with low back pain: a 3.5-year follow-up study"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3611-7929","authenticated-orcid":false,"given":"Xinyi","family":"Ren","sequence":"first","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Clinical School, Monash University , Melbourne, VIC 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Health, The University of Sydney , Sydney, NSW 3150,","place":["Australia"]},{"name":"Institute for Musculoskeletal Health, Sydney Local Health District and University of Sydney , Sydney, NSW 3150,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5341-1055","authenticated-orcid":false,"given":"Suzanne","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Monash Addiction Research Centre, Eastern Clinical School, Monash University , Melbourne, VIC 3199,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2617-9339","authenticated-orcid":false,"given":"Alex","family":"Collie","sequence":"additional","affiliation":[{"name":"Healthy Working Lives Research Group, School of Public Health and Preventive Medicine, Monash University , Melbourne, VIC 3004,","place":["Australia"]},{"name":"Australian and New Zealand Centre of Research Excellence in 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