{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:10:29Z","timestamp":1780387829546,"version":"3.54.1"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Sheikh Shakhbout Medical City"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Neuromodulation via transcutaneous electrical stimulation shows promise in fibromyalgia, but conventional devices have limited coverage. The EXOPULSE Mollii Suit is a full-body garment with 58 electrodes, potentially addressing widespread pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated repeated Mollii Suit sessions on disease impact, pain, and fibromyalgia-related symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This study consisted of a randomized, sham-controlled crossover phase and an open-label phase.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Inclusion occurred in a hospital setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Adults with fibromyalgia were enrolled.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>In this double-blind, randomized, sham-controlled crossover trial (phase 1), participants received 2\u00a0weeks of daily active or sham stimulation (1\u2009h\/day), followed by a \u22652-week washout and crossover. A 4-week open-label extension (phase 2) was proposed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>The primary outcome was the Fibromyalgia Impact Questionnaire (FIQtotal). Secondary outcomes included pain, anxiety, depression, and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-two patients completed phase 1 and 20 completed phase 2. In phase 1, FIQtotal scores significantly decreased following the active intervention (66.06\u2009\u00b1\u200913.46 to 50.81\u2009\u00b1\u200923.22, Friedman\u2019s P\u2009&amp;lt;\u2009.01, Bonferroni-adjusted Dunn\u2019s P\u2009&amp;lt;\u2009.05), whereas no significant effects were observed following the sham intervention. Improvements were also observed in several secondary measures (pain catastrophizing and some quality of life domains). Phase 2 also revealed significant benefits in FIQtotal as well as several secondary outcomes. No severe adverse events occurred at any time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EXOPULSE Mollii Suit led to clinically meaningful improvements in fibromyalgia impact and related outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance<\/jats:title>\n                    <jats:p>The results of this work are in line with those of previous trials and support its potential as a home-based neuromodulation therapy for fibromyalgia. Future large-scale studies would help further understand the effects of this medical device.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/pm\/pnag010","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T12:45:38Z","timestamp":1768999538000},"page":"660-670","source":"Crossref","is-referenced-by-count":0,"title":["The effects of EXOPULSE Mollii Suit in patients with fibromyalgia: a double-blind randomized sham-controlled trial (EXOFIB2)"],"prefix":"10.1093","volume":"27","author":[{"given":"Naji","family":"Riachi","sequence":"first","affiliation":[{"name":"Neurology Division, Sheikh Shakhbout Medical City , Abu Dhabi, UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Shatila","sequence":"additional","affiliation":[{"name":"Neurology Division, Sheikh Shakhbout Medical City , Abu Dhabi, 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des NeuroSciences (ICVNS) , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pascal","family":"Lefaucheur","sequence":"additional","affiliation":[{"name":"UR 4391, Equipe Excitabilit\u00e9 Nerveuse and Th\u00e9rapeutique (ENT), Facult\u00e9 de Sant\u00e9, Universit\u00e9 Paris Est Cr\u00e9teil , Cr\u00e9teil,","place":["France"]},{"name":"Unit\u00e9 de Neurophysiologie Clinique, H\u00f4pital Henri Mondor, Assistance Publique - H\u00f4pitaux de Paris , Cr\u00e9teil,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0880-8608","authenticated-orcid":false,"given":"Moussa A","family":"Chalah","sequence":"additional","affiliation":[{"name":"Institut de la Colonne Vert\u00e9brale et des NeuroSciences (ICVNS) , Paris,","place":["France"]},{"name":"Department of Neurology, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University , Byblos,","place":["Lebanon"]},{"name":"Institut de Neuromodulation, Service Hospitalo-Universitaire, P\u00f4le Hospitalo-Universitaire Psychiatrie Paris 15, H\u00f4pital Sainte-Anne, GHU Paris Psychiatrie et Neurosciences , Paris,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samar S","family":"Ayache","sequence":"additional","affiliation":[{"name":"Institut de la Colonne Vert\u00e9brale et des NeuroSciences (ICVNS) , Paris,","place":["France"]},{"name":"Unit\u00e9 de Neurophysiologie Clinique, H\u00f4pital Henri Mondor, Assistance Publique - H\u00f4pitaux de Paris , Cr\u00e9teil,","place":["France"]},{"name":"Department of Neurology, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University , 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