{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T08:28:26Z","timestamp":1793608106447,"version":"4.5.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine whether Dermabond (2-octyl cyanoacrylate) provides superior lead stability to suture for percutaneous spinal cord stimulator (SCS) trial leads, and whether migration reflects patient-level factors rather than anchoring method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective, randomized, within-patient controlled trial (ClinicalTrials.gov NCT05914311).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Interventional Pain and Spine Medicine Center at an academic medical center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects<\/jats:title>\n                    <jats:p>Forty-eight adults (96 leads) undergoing bilateral thoracic percutaneous SCS trial implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Within each patient, one lead was randomized to Dermabond and the contralateral lead to suture. The primary outcome was absolute radiographic lead migration (mm) between placement and end-of-trial, both imaged upright. All analyses accounted for within-patient correlation; a post hoc non-inferiority framing used the a priori 9\u2009mm clinically meaningful threshold.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean absolute migration was 9.15\u2009\u00b1\u200914.49\u2009mm (Dermabond) and 10.60\u2009\u00b1\u200917.42\u2009mm (suture); the paired difference was \u22121.46\u2009mm (95% CI, \u22126.73 to 3.81; P\u2009=\u2009.58), with the upper bound well below the 9\u2009mm threshold. In adjusted analyses, male sex (+8.17\u2009mm; P\u2009=\u2009.036) and prior spine surgery (+7.08\u2009mm; P\u2009=\u2009.048) predicted greater migration; body mass index (BMI), age, and fixation method did not. Clinically significant (\u22659\u2009mm) migration occurred in 27.1% of Dermabond and 22.9% of suture leads (McNemar P\u2009=\u2009.77).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Dermabond was not superior to suture but showed clinically comparable stability, supporting it as a noninvasive alternative. The stronger signal was at the patient level: male sex and prior spine surgery, but not BMI, predicted migration. Future efforts to reduce migration should target patient-level drivers rather than anchor choice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration number<\/jats:title>\n                    <jats:p>ClinicalTrials.gov NCT05914311 (registered a priori).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/pm\/pnag083","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T11:49:20Z","timestamp":1782992960000},"page":"1221-1230","source":"Crossref","is-referenced-by-count":0,"title":["Dermabond versus suture fixation for spinal cord stimulator trial lead anchoring: a randomized within-patient controlled trial"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6591-9390","authenticated-orcid":false,"given":"Robert W","family":"Hurley","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Wake Forest University School 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