{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:59:25Z","timestamp":1790686765388,"version":"4.1.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Low back pain (LBP) is a leading cause of pain and disability worldwide. Recent studies demonstrate a vertebrogenic model involving the basivertebral nerve (BVN) as a cause of chronic LBP. Vertebral endplates are highly innervated by the BVN, and literature shows that type 1 and 2 Modic changes at vertebral endplates are a source of vertebrogenic low back pain (VBP). As a result, intraosseous radiofrequency ablation of the BVN is a minimally invasive outpatient procedure used to treat VBP. We conducted a retrospective review of 1145 patients that have undergone BVN ablation to assess for safety and complication management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Chart reviews were conducted to obtain demographic and pre-procedural information regarding patient gender, age at the time of BVN ablation, duration of LBP, and BMI. Post-procedure information derived from chart notes included vertebral levels ablated and post-BVN ablation complications, which were categorized as increased LBP &amp;gt; 7\u2009days, increased radicular pain &amp;gt; 7\u2009days, lower extremity weakness, infection, vertebral compression fracture, superficial bleeding, spinal or epidural hematoma, serious neurological injury, visit to the ER, and deep vein thrombosis\/clot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1145 patient charts were reviewed showing an overall complication rate of 3.2% (37 complications). Increased radicular pain was the most common complication at 2.2% (25 complications) and resolved completely in all but 1 patient. The overall complication rate fell to 1.1% (13 complications) when the 24 cases of transient radicular pain were not counted as adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this multicenter retrospective review, the overall rate of complications related to BVN ablation was low (3.2%). The most common complication was temporary radicular pain that resolved with conservative care. These findings suggest that BVN ablation is a safe treatment for VBP in real-world clinical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/pm\/pnag122","type":"journal-article","created":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T11:36:32Z","timestamp":1789817792000},"source":"Crossref","is-referenced-by-count":0,"title":["Analysis of complications associated with basivertebral nerve ablation for vertebrogenic low back pain: a multicenter retrospective cohort study of 1145 patients"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7726-0763","authenticated-orcid":false,"given":"Bryan C","family":"Hoelzer","sequence":"first","affiliation":[{"name":"Southwest Spine and Pain Center , Vineyard, UT,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Acelan","family":"Obray","sequence":"additional","affiliation":[{"name":"Southwest Spine and Pain Center , Vineyard, UT,","place":["United 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and Perioperative Medicine, Mayo Clinic , Rochester, MN,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oludare","family":"Olatoye","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Mayo Clinic , Rochester, MN,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Freeman","sequence":"additional","affiliation":[{"name":"Southwest Spine and Pain Center , Vineyard, UT,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikayla","family":"Parker","sequence":"additional","affiliation":[{"name":"Southwest Spine and Pain Center , Vineyard, UT,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellie A","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Southwest Spine and Pain Center , Vineyard, UT,","place":["United 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Orthopedics , Hutchinson, MN,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley L","family":"Hamann","sequence":"additional","affiliation":[{"name":"Pacific Sports & Spine , Springfield, OR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace G","family":"Carson","sequence":"additional","affiliation":[{"name":"Pacific Sports & Spine , Springfield, OR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa S","family":"Mayeri","sequence":"additional","affiliation":[{"name":"Pacific Sports & Spine , Springfield, OR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candance M","family":"Peterson","sequence":"additional","affiliation":[{"name":"Pacific Sports & Spine , Springfield, OR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayden 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