{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:53:04Z","timestamp":1789228384141,"version":"build-2803163510"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Med"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1093\/pm\/pnw012","type":"journal-article","created":{"date-parts":[[2016,3,20]],"date-time":"2016-03-20T01:03:11Z","timestamp":1458435791000},"page":"1933-1941","source":"Crossref","is-referenced-by-count":8,"title":["SoluMatrix<sup>\u00ae<\/sup>Diclofenac: Sustained Opioid-Sparing Effects in a Phase 3 Study in Patients with Postoperative Pain"],"prefix":"10.1093","volume":"17","author":[{"given":"Charles","family":"Argoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bill","family":"McCarberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Gudin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas","family":"Nalamachu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarence","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,3,19]]},"reference":[{"key":"2016101306323856000_17.10.1933.1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3810\/pgm.2011.03.2270","article-title":"Pain management in primary care: Strategies to mitigate opioid misuse, abuse, and diversion","volume":"123","author":"McCarberg","year":"2011","journal-title":"Postgrad Med"},{"key":"2016101306323856000_17.10.1933.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03318.x"},{"key":"2016101306323856000_17.10.1933.3","doi-asserted-by":"publisher","DOI":"10.1002\/art.23177"},{"key":"2016101306323856000_17.10.1933.4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00003643-199705001-00003","article-title":"Mechanisms of actions of opioids and non-steroidal anti-inflammatory drugs","volume":"15","author":"Bovill","year":"1997","journal-title":"Eur J Anaesthesiol Suppl"},{"key":"2016101306323856000_17.10.1933.5","unstructured":"Institute of Medicine (US) Committee on Advancing Pain Research, Care, and Education. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research. Washington, DC: National Academies Press (US); 2011."},{"key":"2016101306323856000_17.10.1933.6","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1111\/pme.12289","article-title":"NSAIDs or opioids, damned if you do, damned if you don't?: Evidence-based selections to optimize therapeutic goals and minimize harms","volume":"14(suppl 1)","author":"Argoff","year":"2013","journal-title":"Pain Med"},{"key":"2016101306323856000_17.10.1933.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1406143"},{"key":"2016101306323856000_17.10.1933.8","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.36076\/ppj.2008\/11\/S105","article-title":"Opioid complications and side effects","volume":"11","author":"Benyamin","year":"2008","journal-title":"Pain Physician"},{"key":"2016101306323856000_17.10.1933.9","doi-asserted-by":"publisher","DOI":"10.1177\/2049463712436536"},{"key":"2016101306323856000_17.10.1933.10","doi-asserted-by":"publisher","DOI":"10.1186\/ar1782"},{"key":"2016101306323856000_17.10.1933.11","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.391"},{"key":"2016101306323856000_17.10.1933.12","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2014.921610"},{"key":"2016101306323856000_17.10.1933.13","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31825c049f"},{"key":"2016101306323856000_17.10.1933.14","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.1827"},{"key":"2016101306323856000_17.10.1933.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2014.03.001"},{"key":"2016101306323856000_17.10.1933.16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/JPR.S75234","article-title":"Assessment of rescue opioid use in patients with post-bunionectomy pain treated with diclofenac potassium liquid-filled capsules","volume":"8:","author":"Willens","year":"2015","journal-title":"J Pain Res"},{"key":"2016101306323856000_17.10.1933.17","doi-asserted-by":"publisher","DOI":"10.3310\/hta14220"},{"key":"2016101306323856000_17.10.1933.18","doi-asserted-by":"publisher","DOI":"10.1007\/BF03261999"},{"key":"2016101306323856000_17.10.1933.19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pmed.1001098","article-title":"Cardiovascular risk with non-steroidal anti-inflammatory drugs: Systematic review of population-based controlled observational studies","volume":"8","author":"McGettigan","year":"2011","journal-title":"PLoS Med"},{"key":"2016101306323856000_17.10.1933.20","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2004.12.005"},{"key":"2016101306323856000_17.10.1933.21","unstructured":"Food and Drug Administration. Public Health Advisory\u2014FDA Announces Important Changes and Additional Warnings for COX-2 Selective and Non-Selective Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). 2005. US Food and Drug Administration. Silver Spring, MD. Available at: http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm150314.htm. Page last updated 16 Aug 2013 (accessed 4 February 2016)."},{"key":"2016101306323856000_17.10.1933.22","unstructured":"European Medicines Agency Press Office. Press Release: European Medicines Agency Concludes Action on COX-2 Inhibitors. London, UK: European Medicines Agency; 2005."},{"key":"2016101306323856000_17.10.1933.23","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000160005.90598.41"},{"key":"2016101306323856000_17.10.1933.24","unstructured":"Food and Drug Administration . FDA Drug Safety Communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokes. 2015. Available at: http:\/\/www.fda.gov\/Drugs\/DrugSafety\/ucm451800.htm. Page last updated 09 July 2015 (accessed 16 January 2016)."},{"key":"2016101306323856000_17.10.1933.25","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2013.09.2693"},{"key":"2016101306323856000_17.10.1933.26","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2014.946123"},{"key":"2016101306323856000_17.10.1933.27","unstructured":"Iroko Pharmaceuticals, LLC. ZORVOLEX Full Prescribing Information. Available at: http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2014\/204592s002s004lbl.pdf. Last updated 08 January 2014 (accessed 02 February 2016)."},{"key":"2016101306323856000_17.10.1933.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2014.10.018"},{"key":"2016101306323856000_17.10.1933.29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.23.3043"},{"key":"2016101306323856000_17.10.1933.30","doi-asserted-by":"publisher","DOI":"10.7547\/0940305"},{"key":"2016101306323856000_17.10.1933.31","doi-asserted-by":"publisher","DOI":"10.7547\/0960393"},{"key":"2016101306323856000_17.10.1933.32","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-011-0052-y"},{"key":"2016101306323856000_17.10.1933.33","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2012.694363"},{"key":"2016101306323856000_17.10.1933.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.09.002"},{"key":"2016101306323856000_17.10.1933.35","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2009.09.011"},{"key":"2016101306323856000_17.10.1933.36","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2010.515478"}],"container-title":["Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/painmedicine\/article-pdf\/17\/10\/1933\/8021842\/pnw012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T18:41:29Z","timestamp":1655318489000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/painmedicine\/article-lookup\/doi\/10.1093\/pm\/pnw012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,19]]},"references-count":36,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,10,13]]},"published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1093\/pm\/pnw012"],"URL":"https:\/\/doi.org\/10.1093\/pm\/pnw012","relation":{},"ISSN":["1526-2375","1526-4637"],"issn-type":[{"value":"1526-2375","type":"print"},{"value":"1526-4637","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,19]]}}}