{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T03:51:47Z","timestamp":1781322707505,"version":"3.54.1"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T00:00:00Z","timestamp":1545782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Department of Defense\/Defense Health","award":["D61_I_10_J5_148"],"award-info":[{"award-number":["D61_I_10_J5_148"]}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2 TR001118"],"award-info":[{"award-number":["KL2 TR001118"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to examine the effect of pain severity on activity levels and physical disability in the context of high pain acceptance. We hypothesized that pain acceptance moderates the effect of pain severity on general activity and physical disability, such that at higher levels of acceptance, the deleterious effect of pain is mitigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two hundred seven patients with chronic pain were recruited from three clinics in a large southwestern military treatment facility. Participants completed an anonymous self-report battery of standardized measures, including the Chronic Pain Acceptance Questionnaire, modified Oswestry Disability Index, and Pain Severity and General Activity subscales of the West Haven-Yale Multidimensional Pain Inventory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Chronic pain acceptance was found to significantly moderate relations between pain severity and general activity (b \u2009= \u20090.0061, t(198) = 2.75, P = 0.007, 95% confidence interval [CI] = 0.002 to 0.011) and pain severity and disability (b \u2009= \u20090.036, t(193) = \u20132.564, P = 0.011, 95% CI = \u20130.063 to \u20130.008). In the context of higher acceptance, the negative effect of pain on activity and disability appeared reduced. Conversely, in the context of low acceptance, the effect of pain on disability appeared accentuated at all levels of pain severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Higher acceptance mitigated both activity level and disability in a military-affiliated clinical sample of patients with chronic pain. Results further establish the role of acceptance in relation to functioning in a unique sample of people with chronic pain. These findings have implications for understanding and enhancing functioning in chronic pain populations.<\/jats:p><\/jats:sec>","DOI":"10.1093\/pm\/pny197","type":"journal-article","created":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T03:14:13Z","timestamp":1536203653000},"page":"1509-1518","source":"Crossref","is-referenced-by-count":19,"title":["Mitigating the Effect of Pain Severity on Activity and Disability in Patients with Chronic Pain: The Crucial Context of Acceptance"],"prefix":"10.1093","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7253-7067","authenticated-orcid":false,"given":"Kathryn E","family":"Kanzler","sequence":"first","affiliation":[{"name":"Department of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas"},{"name":"Department of Family and Community Medicine, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline A","family":"Pugh","sequence":"additional","affiliation":[{"name":"South Texas Veterans Health Care System"},{"name":"Department of Medicine, University of Texas Health Science Center San Antonio, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald D","family":"McGeary","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas"},{"name":"Department of Family and Community Medicine, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willie J","family":"Hale","sequence":"additional","affiliation":[{"name":"Department of Psychology, The University of Texas at San Antonio, San Antonio, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles W","family":"Mathias","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa S","family":"Kilpela","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara E","family":"Karns-Wright","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia J","family":"Robinson","sequence":"additional","affiliation":[{"name":"Mountainview Consulting Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara A","family":"Dixon","sequence":"additional","affiliation":[{"name":"81 DS\/SGD Orofacial Pain, 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