{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T22:09:36Z","timestamp":1792534176324,"version":"4.5.0"},"reference-count":95,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:00:00Z","timestamp":1557187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the effectiveness of a biobehavioral approach with and without orthopedic manual physical therapy on the intensity and frequency of pain in patients diagnosed with nonspecific chronic low back pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single-blind randomized controlled trial. Fifty patients were randomly allocated into two groups: one group received biobehavioral therapy with orthopedic manual physical therapy, and the other group received only biobehavioral therapy. Both groups completed a total of eight sessions, with a frequency of two sessions per week. The somatosensory, physical, and psychological variables were recorded at baseline and during the first and third month after initiation of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In both groups, the treatment was effective, presenting significant differences for all the variables in the time factor. There were no significant differences between groups in intensity or frequency of pain, with a large effect size (&amp;gt;0.80), but there were intragroup differences for both intervention groups at one- and three-month follow-up. There were also no significant differences between groups in the secondary variables during the same follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of this study suggest that orthopedic manual physical therapy does not increase the effects of a treatment based on biobehavioral therapy in the short or medium term, but these results should be interpreted with caution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/pm\/pnz093","type":"journal-article","created":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T11:17:01Z","timestamp":1553599021000},"page":"2571-2587","source":"Crossref","is-referenced-by-count":32,"title":["Physiotherapy Based on a Biobehavioral Approach with or Without Orthopedic Manual Physical Therapy in the Treatment of Nonspecific Chronic Low Back Pain: A Randomized Controlled Trial"],"prefix":"10.1093","volume":"20","author":[{"given":"M\u00f3nica","family":"Grande-Alonso","sequence":"first","affiliation":[{"name":"Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Motion in Brains Research Group, Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Suso-Mart\u00ed","sequence":"additional","affiliation":[{"name":"Motion in Brains Research Group, Institute of Neuroscience and Sciences of the Movement (INCIMOV), Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Department of Physiotherapy, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Cuenca-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Motion in Brains Research Group, Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Pardo-Montero","sequence":"additional","affiliation":[{"name":"Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Motion in Brains Research Group, Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Instituto de Neurociencia y Dolor Craneofacial (INDCRAN), Madrid, Espa\u00f1a"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Espa\u00f1a"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Gil-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Motion in Brains Research Group, Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Instituto de Neurociencia y Dolor Craneofacial (INDCRAN), Madrid, Espa\u00f1a"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Espa\u00f1a"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"La Touche","sequence":"additional","affiliation":[{"name":"Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Motion in Brains Research Group, Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Aut\u00f3noma de Madrid, Aravaca, Madrid, Spain"},{"name":"Instituto de Neurociencia y Dolor Craneofacial (INDCRAN), Madrid, Espa\u00f1a"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Espa\u00f1a"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,5,7]]},"reference":[{"issue":"6","key":"2020013005464968100_pnz093-B1","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jbspin.2009.07.003","article-title":"Epidemiology of low back pain: What\u2019s new?","volume":"76","author":"Rossignol","year":"2009","journal-title":"Joint Bone Spine"},{"issue":"5\u20136","key":"2020013005464968100_pnz093-B2","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0160-2527(99)00022-9","article-title":"Back pain: Delimiting the problem in the next millennium","volume":"22","author":"Nachemson","year":"1999","journal-title":"Int J Law Psychiatry"},{"issue":"6","key":"2020013005464968100_pnz093-B3","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1002\/art.34347","article-title":"A systematic review of the global prevalence of low back pain","volume":"64","author":"Hoy","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"2","key":"2020013005464968100_pnz093-B4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1054\/math.2002.0442","article-title":"Forebrain-mediated sensitization of central pain pathways: \u201cNon-specific\u201d pain and a new image for MT","volume":"7","author":"Zusman","year":"2002","journal-title":"Man Ther"},{"issue":"9","key":"2020013005464968100_pnz093-B5","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1093\/brain\/awt211","article-title":"Shape shifting pain: Chronification of back pain shifts brain representation from nociceptive to emotional circuits","volume":"136","author":"Hashmi","year":"2013","journal-title":"Brain"},{"issue":"5","key":"2020013005464968100_pnz093-B6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.math.2008.09.001","article-title":"The mechanisms of manual therapy in the treatment of musculoskeletal pain: A comprehensive model","volume":"14","author":"Bialosky","year":"2009","journal-title":"Man Ther"},{"issue":"1","key":"2020013005464968100_pnz093-B7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jmpt.2005.10.002","article-title":"Spinal manipulative therapy reduces inflammatory cytokines but not substance P production in normal subjects","volume":"29","author":"Teodorczyk-Injeyan","year":"2006","journal-title":"J Manipulative Physiol Ther"},{"issue":"7","key":"2020013005464968100_pnz093-B8","first-page":"448","article-title":"An investigation of the interrelationship between manipulative therapy-induced hypoalgesia and sympathoexcitation","volume":"21","author":"Vicenzino","year":"1998","journal-title":"J Manip Physiol Ther"},{"issue":"4444","key":"2020013005464968100_pnz093-B9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1126\/science.7367889","article-title":"Opioid and nonopioid mechanisms of stress analgesia","volume":"208","author":"Lewis","year":"1980","journal-title":"Science"},{"issue":"2","key":"2020013005464968100_pnz093-B10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2165\/00007256-200029020-00002","article-title":"Analgesia following exercise: A review","volume":"29","author":"Koltyn","year":"2000","journal-title":"Sports Med"},{"issue":"14","key":"2020013005464968100_pnz093-B11","doi-asserted-by":"crossref","first-page":"6329","DOI":"10.1073\/pnas.91.14.6329","article-title":"Central effects of baroreceptor activation in humans: Attenuation of skeletal reflexes and pain perception","volume":"91","author":"Dworkin","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"2020013005464968100_pnz093-B12","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s00421-007-0469-9","article-title":"The effect of physical therapy on beta-endorphin levels","volume":"100","author":"Bender","year":"2007","journal-title":"Eur J Appl Physiol"},{"issue":"6","key":"2020013005464968100_pnz093-B13","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.psyneuen.2011.09.017","article-title":"Intense exercise increases circulating endocannabinoid and BDNF levels in humans\u2014possible implications for reward and depression","volume":"37","author":"Heyman","year":"2012","journal-title":"Psychoneuroendocrinology"},{"issue":"7","key":"2020013005464968100_pnz093-B14","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1007\/s00421-011-2237-0","article-title":"Effects of exercise stress on the endocannabinoid system in humans under field conditions","volume":"112","author":"Feuerecker","year":"2012","journal-title":"Eur J Appl Physiol"},{"issue":"5","key":"2020013005464968100_pnz093-B15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0301-0082(00)00031-9","article-title":"Cannabinoid receptors and pain","volume":"63","author":"Pertwee","year":"2001","journal-title":"Prog Neurobiol"},{"issue":"5","key":"2020013005464968100_pnz093-B16","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.math.2011.04.005","article-title":"How to explain central sensitization to patients with \u2018unexplained\u2019 chronic musculoskeletal pain: Practice guidelines","volume":"16","author":"Nijs","year":"2011","journal-title":"Man Ther"},{"key":"2020013005464968100_pnz093-B17","doi-asserted-by":"crossref","DOI":"10.3109\/09593985.2015.1138010","article-title":"The relationship between knowledge of pain neurophysiology and fear avoidance in people with chronic pain: A point in time, observational study","author":"Fletcher","year":"2016","journal-title":"Physiother Theory Pract"},{"key":"2020013005464968100_pnz093-B18","first-page":"371","article-title":"Assessing the role of cognitive behavioral therapy in the management of chronic nonspecific back pain","volume":"5","author":"Sveinsdottir","year":"2012","journal-title":"J Pain Res"},{"issue":"4","key":"2020013005464968100_pnz093-B19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jpain.2005.10.011","article-title":"Reduction of pain catastrophizing mediates the outcome of both physical and cognitive-behavioral treatment in chronic low back pain","volume":"7","author":"Smeets","year":"2006","journal-title":"J Pain"},{"issue":"12","key":"2020013005464968100_pnz093-B20","first-page":"2519","article-title":"Effectiveness and cost-effectiveness of adding a cognitive behavioral treatment to the rehabilitation of chronic low back pain","volume":"33","author":"Schweikert","year":"2006","journal-title":"J Rheumatol"},{"issue":"3","key":"2020013005464968100_pnz093-B21","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s10942-015-0215-x","article-title":"Behavioral and cognitive\u2014behavioral approaches to treating patients with chronic pain: Thinking outside the pill box","volume":"33","author":"Okifuji","year":"2015","journal-title":"J Ration Cogn Ther"},{"key":"2020013005464968100_pnz093-B22","article-title":"Pain management using a multimodal physiotherapy program including a biobehavioral approach for chronic nonspecific neck pain: A randomized controlled trial","author":"L\u00f3pez-de-Uralde-Villanueva","year":"2018","journal-title":"Physiother Theory Pract"},{"issue":"7","key":"2020013005464968100_pnz093-B23","first-page":"CD002014.","article-title":"Behavioural treatment for chronic low-back pain (Review)","volume":"7","author":"Henschke","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"2020013005464968100_pnz093-B24","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1097\/00115550-200311000-00016","article-title":"Cognitive-behavioral approach to the treatment of chronic pain patients","volume":"28","author":"Turk","year":"2003","journal-title":"Reg Anesth Pain Med"},{"issue":"1","key":"2020013005464968100_pnz093-B25","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.2044-8260.1995.tb01443.x","article-title":"Behavioural rehabilitation of chronic low back pain: Comparison of an operant treatment, an operant-cognitive treatment and an operant-respondent treatment","volume":"34","author":"Vlaeyen","year":"1995","journal-title":"Br J Clin Psychol"},{"key":"2020013005464968100_pnz093-B26","author":"Linton"},{"issue":"6","key":"2020013005464968100_pnz093-B27","doi-asserted-by":"crossref","first-page":"289","DOI":"10.12968\/ijtr.2016.23.6.289","article-title":"Relaxation and chronic pain: A critical review","volume":"23","author":"Jeffrey","year":"2016","journal-title":"Int J Ther Rehabil"},{"issue":"11","key":"2020013005464968100_pnz093-B28","doi-asserted-by":"crossref","first-page":"726","DOI":"10.7326\/0003-4819-152-11-201006010-00232","article-title":"Group C. CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials","volume":"152","author":"Schulz","year":"2010","journal-title":"Ann Intern Med"},{"key":"2020013005464968100_pnz093-B29","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1136\/bmj.b1805","article-title":"Early management of persistent non-specific low back pain: Summary of NICE guidance","volume":"338","author":"Savigny","year":"2009","journal-title":"BMJ"},{"issue":"12","key":"2020013005464968100_pnz093-B30","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1111\/j.1553-2712.2001.tb01132.x","article-title":"Reliability of the visual analog scale for measurement of acute pain","volume":"8","author":"Bijur","year":"2001","journal-title":"Acad Emerg Med"},{"issue":"1","key":"2020013005464968100_pnz093-B31","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/BRS.0b013e31815e3a10","article-title":"Interpreting change scores for pain and functional status in low back pain","volume":"33","author":"Ostelo","year":"2008","journal-title":"Spine"},{"key":"2020013005464968100_pnz093-B32","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.apnr.2015.03.013","article-title":"Methods to measure peripheral and central sensitization using quantitative sensory testing: A focus on individuals with low back pain","volume":"29","author":"Starkweather","year":"2016","journal-title":"Appl Nurs Res"},{"issue":"3","key":"2020013005464968100_pnz093-B33","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.pain.2010.05.002","article-title":"Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes","volume":"150","author":"Maier","year":"2010","journal-title":"Pain"},{"issue":"10","key":"2020013005464968100_pnz093-B34","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1097\/j.pain.0000000000000254","article-title":"Is temporal summation of pain and spinal nociception altered during normal aging?","volume":"156","author":"Marouf","year":"2015","journal-title":"Pain"},{"issue":"2","key":"2020013005464968100_pnz093-B35","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1093\/ptj\/65.2.181","article-title":"Quantitative measure of cutaneous sensation. Two-point discrimination values for the face and trunk","volume":"65","author":"Nolan","year":"1985","journal-title":"Phys Ther"},{"issue":"8","key":"2020013005464968100_pnz093-B36","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1093\/rheumatology\/ket140","article-title":"Assessing tactile acuity in rheumatology and musculoskeletal medicine\u2014how reliable are two-point discrimination tests at the neck, hand, back and foot?","volume":"52","author":"Catley","year":"2013","journal-title":"Rheumatology"},{"issue":"2","key":"2020013005464968100_pnz093-B37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1067\/mmt.2001.112563","article-title":"Isometric back extension endurance tests: A review of the literature","volume":"24","author":"Moreau","year":"2001","journal-title":"J Manip Physiol Ther"},{"issue":"1","key":"2020013005464968100_pnz093-B38","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0003-9993(96)90224-5","article-title":"Lumbar trunk muscle endurance testing: An inexpensive","volume":"77","author":"Ito","year":"1996","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"2020013005464968100_pnz093-B39","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jmpt.2012.12.008","article-title":"Intraexaminer and interexaminer reliability of pressure biofeedback unit for assessing lumbopelvic stability during 6 lower limb movement tests","volume":"36","author":"Azevedo","year":"2013","journal-title":"J Manip Physiol Ther"},{"key":"2020013005464968100_pnz093-B40","volume-title":"Operating Instructions","author":"Chattanooga Group","year":"2005"},{"issue":"5","key":"2020013005464968100_pnz093-B41","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/00007632-200203010-00016","article-title":"Validation of the Spanish version of the Roland-Morris questionnaire","volume":"27","author":"Kovacs","year":"2002","journal-title":"Spine"},{"issue":"24","key":"2020013005464968100_pnz093-B42","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1097\/00007632-200012150-00006","article-title":"The Roland-Morris Disability Questionnaire and the Oswestry Disability Questionnaire","volume":"25","author":"Roland","year":"2000","journal-title":"Spine"},{"issue":"4","key":"2020013005464968100_pnz093-B43","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1093\/ptj\/76.4.359","article-title":"Defining the minimum level of detectable change for the Roland Morris Questionnaire","volume":"76","author":"Stratford","year":"1996","journal-title":"Phys Ther"},{"issue":"4","key":"2020013005464968100_pnz093-B44","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jpain.2010.08.004","article-title":"Psychometric properties of the Spanish version of the Tampa Scale for Kinesiophobia (TSK)","volume":"12","author":"G\u00f3mez-P\u00e9rez","year":"2011","journal-title":"J Pain"},{"issue":"13","key":"2020013005464968100_pnz093-B45","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1157\/13127277","article-title":"Validation of the Spanish version of the Pain Catastrophizing Scale in fibromyalgia","volume":"131","author":"Garc\u00eda Campayo","year":"2008","journal-title":"Med Cl\u00ednica"},{"issue":"4","key":"2020013005464968100_pnz093-B46","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2519\/jospt.2010.3298","article-title":"A psychometric investigation of fear-avoidance model measures in patients with chronic low back pain","volume":"40","author":"George","year":"2010","journal-title":"J Orthop Sport Phys Ther"},{"issue":"1\u20132","key":"2020013005464968100_pnz093-B47","first-page":"53","article-title":"Percepci\u00f3n de autoeficacia en dolor cr\u00f3nico. Adaptaci\u00f3n y validaci\u00f3n de la Chronic Pain Self-Efficacy Scale","volume":"11","author":"Mart\u00edn-Arag\u00f3n Gelabert","year":"1999","journal-title":"Rev Psicol Salud"},{"issue":"1","key":"2020013005464968100_pnz093-B48","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(95)00021-J","article-title":"Development and initial validation of a scale to measure self-efficacy beliefs in patients with chronic pain","volume":"63","author":"Anderson","year":"1995","journal-title":"Pain"},{"key":"2020013005464968100_pnz093-B49","author":"Kamper"},{"issue":"1","key":"2020013005464968100_pnz093-B50","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1177\/001316447303300111","article-title":"Eta-squared and partial eta-squared in fixed factor ANOVA designs","volume":"33","author":"Cohen","year":"1973","journal-title":"Educ Psychol Meas"},{"issue":"6","key":"2020013005464968100_pnz093-B51","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/01.BRS.0000049921.04200.A6","article-title":"Manual therapy and exercise therapy in patients with chronic low back pain","volume":"28","author":"Aure","year":"2003","journal-title":"Spine"},{"issue":"4","key":"2020013005464968100_pnz093-B52","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0004-9514(14)60169-0","article-title":"Combined physiotherapy and education is efficacious for chronic low back pain","volume":"48","author":"Moseley","year":"2002","journal-title":"Aust J Physiother"},{"issue":"7","key":"2020013005464968100_pnz093-B53","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.spinee.2011.01.036","article-title":"Supervised exercise, spinal manipulation, and home exercise for chronic low back pain: A randomized clinical trial","volume":"11","author":"Bronfort","year":"2011","journal-title":"Spine J"},{"issue":"18","key":"2020013005464968100_pnz093-B54","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1097\/BRS.0b013e3181f5dfe0","article-title":"Does maintained spinal manipulation therapy for chronic nonspecific low back pain result in better long-term outcome?","volume":"36","author":"Senna","year":"2011","journal-title":"Spine"},{"key":"2020013005464968100_pnz093-B55","first-page":"CD012087.","article-title":"Non-steroidal anti-inflammatory drugs for chronic low back pain","volume":"2","author":"Enthoven","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"2020013005464968100_pnz093-B56","first-page":"572","article-title":"Top 20 research studies of 2016 for primary care physicians","volume":"95","author":"Ebell","year":"2017","journal-title":"Am Fam Physician"},{"issue":"10","key":"2020013005464968100_pnz093-B57","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1097\/PHM.0000000000000293","article-title":"Manual therapy, therapeutic patient education, and therapeutic exercise, an effective multimodal treatment of nonspecific chronic neck pain","volume":"94","author":"Beltran-Alacreu","year":"2015","journal-title":"Am J Phys Med Rehabil"},{"issue":"1","key":"2020013005464968100_pnz093-B58","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/1471-2474-11-238","article-title":"Efficacy of a multimodal physiotherapy treatment program for hip osteoarthritis: A randomised placebo-controlled trial protocol","volume":"11","author":"Bennell","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"2020013005464968100_pnz093-B59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/09638288.2016.1236155","article-title":"Physiotherapist-delivered cognitive-behavioural interventions are effective for low back pain, but can they be replicated in clinical practice? A systematic review","volume":"40","author":"Hall","year":"2018","journal-title":"Disabil Rehabil"},{"issue":"7","key":"2020013005464968100_pnz093-B60","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.jpain.2016.01.473","article-title":"Comparative effectiveness of conservative interventions for nonspecific chronic spinal pain: Physical, behavioral\/psychologically informed, or combined? A systematic review and meta-analysis","volume":"17","author":"O\u2019Keeffe","year":"2016","journal-title":"J Pain"},{"issue":"9","key":"2020013005464968100_pnz093-B61","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1080\/09593985.2017.1423522","article-title":"Multimodal physiotherapy treatment based on a biobehavioral approach for patients with chronic cervico-craniofacial pain: A prospective case series","volume":"34","author":"Marcos-Mart\u00edn","year":"2018","journal-title":"Physiother Theory Pract"},{"issue":"12","key":"2020013005464968100_pnz093-B62","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1517\/14656566.2014.925446","article-title":"Treatment of central sensitization in patients with \u2018unexplained\u2019 chronic pain: An update","volume":"15","author":"Nijs","year":"2014","journal-title":"Expert Opin Pharmacother"},{"issue":"5","key":"2020013005464968100_pnz093-B63","first-page":"S108","article-title":"In the spine or in the brain? Recent advances in pain neuroscience applied in the intervention for low back pain","volume":"35","author":"Nijs","year":"2017","journal-title":"Clin Exp Rheumatol"},{"issue":"5472","key":"2020013005464968100_pnz093-B64","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1126\/science.288.5472.1765","article-title":"Neuronal plasticity: Increasing the gain in pain","volume":"288","author":"Woolf","year":"2000","journal-title":"Science"},{"issue":"1","key":"2020013005464968100_pnz093-B65","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1298\/ptr.E9937","article-title":"Effectiveness of classic physical therapy proposals for chronic non-specific low back pain: A literature review","volume":"21","author":"Cuenca-Mart\u00ednez","year":"2018","journal-title":"Phys Ther Res"},{"issue":"5","key":"2020013005464968100_pnz093-B66","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1080\/09593985.2016.1194663","article-title":"Combining manual therapy with pain neuroscience education in the treatment of chronic low back pain: A narrative review of the literature","volume":"32","author":"Puentedura","year":"2016","journal-title":"Physiother Theory Pract"},{"issue":"1","key":"2020013005464968100_pnz093-B67","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3233\/BMR-169723","article-title":"Short-term effects of manipulative treatment versus a therapeutic home exercise protocol for chronic cervical pain: A randomized clinical trial","volume":"31","author":"Galindez-Ibarbengoetxea","year":"2018","journal-title":"J Back Musculoskelet Rehabil"},{"key":"2020013005464968100_pnz093-B68","first-page":"1):916","article-title":"Efficacy of classification-based cognitive functional therapy in patients with non-specific chronic low back pain: A randomized controlled trial","volume":"17","author":"Fersum","year":"2013","journal-title":"Eur J Pain"},{"issue":"8","key":"2020013005464968100_pnz093-B69","doi-asserted-by":"crossref","first-page":"620","DOI":"10.2340\/16501977-0395","article-title":"Association between catastrophizing and self-rated pain and disability in patients with chronic low back pain","volume":"41","author":"Meyer","year":"2009","journal-title":"J Rehabil Med"},{"issue":"3","key":"2020013005464968100_pnz093-B70","first-page":"235","article-title":"Fear and avoidance of movement in people with chronic pain: Psychometric properties of the 11-item Tampa Scale for Kinesiophobia (TSK-11)","volume":"64","author":"Hapidou","year":"2012","journal-title":"Physiother"},{"issue":"3","key":"2020013005464968100_pnz093-B71","first-page":"593","article-title":"Self-efficacy and fear avoidance beliefs in chronic low back pain patients: Coexistence and associated factors. Pain","volume":"15","author":"de Moraes Vieira","year":"2014","journal-title":"Manag Nurs"},{"issue":"1","key":"2020013005464968100_pnz093-B72","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/00002508-200103000-00008","article-title":"Theoretical perspectives on the relation between catastrophizing and pain","volume":"17","author":"Sullivan","year":"2001","journal-title":"Clin J Pain"},{"issue":"2","key":"2020013005464968100_pnz093-B73","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1466-7657.2009.00794.x","article-title":"Evaluation of patient self-management outcomes in health care: A systematic review","volume":"57","author":"Du","year":"2010","journal-title":"Int Nurs Rev"},{"issue":"8","key":"2020013005464968100_pnz093-B74","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.ejpain.2007.01.005","article-title":"The relation between cognitive factors and levels of pain and disability in chronic low back pain patients presenting for physiotherapy","volume":"11","author":"Woby","year":"2007","journal-title":"Eur J Pain"},{"issue":"4","key":"2020013005464968100_pnz093-B75","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.pain.2012.01.007","article-title":"Patients who display protective pain behaviors are viewed as less likable, less dependable, and less likely to return to work","volume":"153","author":"Martel","year":"2012","journal-title":"Pain"},{"key":"2020013005464968100_pnz093-B76","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejpain.2005.01.003","article-title":"Psycho-social factors and coping strategies as predictors of chronic evolution and quality of life in patients with low back pain: A prospective study","author":"Koleck","year":"2006","journal-title":"Eur J Pain"},{"issue":"8","key":"2020013005464968100_pnz093-B77","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.jpain.2014.05.002","article-title":"Self-efficacy and chronic pain outcomes: A meta-analytic review","volume":"15","author":"Jackson","year":"2014","journal-title":"J Pain"},{"key":"2020013005464968100_pnz093-B78","article-title":"Pain self-efficacy and fear of movement are similarly associated with pain intensity and disability in Italian patients with chronic low back pain","author":"Ferrari","journal-title":"Pain Pract"},{"issue":"8","key":"2020013005464968100_pnz093-B79","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1097\/AJP.0000000000000027","article-title":"Associations between psychosocial factors and pain intensity, physical functioning and psychological functioning in patients with chronic pain: A cross-cultural comparison","volume":"30","author":"Ferreira-Valente","year":"2014","journal-title":"Clin J Pain"},{"key":"2020013005464968100_pnz093-B80","article-title":"The influence of self-efficacy, fear-avoidance belief, and coping styles on quality of life for Chinese patients with chronic non-specific low back pain: A multi-site cross-sectional study","author":"Du","journal-title":"Pain Pract"},{"issue":"5","key":"2020013005464968100_pnz093-B81","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1177\/0269215509353264","article-title":"A further investigation of the importance of pain cognition and behaviour in pain rehabilitation: Longitudinal data suggest disability and fear of movement are most important","volume":"24","author":"\u00c5senl\u00f6f","year":"2010","journal-title":"Clin Rehabil"},{"key":"2020013005464968100_pnz093-B82","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1016\/j.msksp.2018.03.007","article-title":"Two-point discrimination and the low back pain: Not as unreliable as it seems, but what about standardised procedures?","volume":"35","author":"Adamczyk","year":"2018","journal-title":"Musculoskelet Sci Pract"},{"issue":"11","key":"2020013005464968100_pnz093-B83","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1371\/journal.pbio.0030362","article-title":"Improvement of tactile discrimination performance and enlargement of cortical somatosensory maps after 5 Hz rTMS","volume":"3","author":"Tegenthoff","year":"2005","journal-title":"PLoS Biol"},{"issue":"3","key":"2020013005464968100_pnz093-B84","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0896-6273(03)00677-9","article-title":"Functional imaging of perceptual learning in human primary and secondary somatosensory cortex","volume":"40","author":"Pleger","year":"2003","journal-title":"Neuron"},{"issue":"21","key":"2020013005464968100_pnz093-B85","doi-asserted-by":"crossref","first-page":"12255","DOI":"10.1073\/pnas.191176298","article-title":"Shifts in cortical representations predict human discrimination improvement","volume":"98","author":"Pleger","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2020013005464968100_pnz093-B86","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.neuroimage.2017.10.016","article-title":"Structural changes in brain morphology induced by brief periods of repetitive sensory stimulation","volume":"165","author":"Schmidt-Wilcke","year":"2018","journal-title":"Neuroimage"},{"issue":"3","key":"2020013005464968100_pnz093-B87","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.pain.2008.12.002","article-title":"Why do some patients keep hurting their back? Evidence of ongoing back muscle dysfunction during remission from recurrent back pain","volume":"142","author":"Macdonald","year":"2009","journal-title":"Pain"},{"issue":"4","key":"2020013005464968100_pnz093-B88","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.jbmt.2014.12.003","article-title":"The effect of motor control and tactile acuity training on patients with non-specific low back pain and movement control impairment","volume":"19","author":"Gutknecht","year":"2015","journal-title":"J Bodyw Mov Ther"},{"issue":"4","key":"2020013005464968100_pnz093-B89","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3233\/BMR-140561","article-title":"A brief intervention utilising visual feedback reduces pain and enhances tactile acuity in CLBP patients","volume":"28","author":"Trapp","year":"2015","journal-title":"J Back Musculoskelet Rehabil"},{"issue":"68","key":"2020013005464968100_pnz093-B90","article-title":"Immediate effects of spinal manipulation on thermal pain sensitivity: An experimental study","volume":"7","author":"George","year":"2006","journal-title":"BMC Musculoskelet Disord"},{"issue":"11","key":"2020013005464968100_pnz093-B91","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1002\/acr.22070","article-title":"Psychological profiles and pain characteristics of older adults with knee osteoarthritis","volume":"65","author":"Cruz-almeida","year":"2013","journal-title":"Arthritis Care Res"},{"issue":"11","key":"2020013005464968100_pnz093-B92","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1093\/aje\/kwf136","article-title":"Pain catastrophizing and kinesiophobia: Predictors of chronic low back pain","volume":"156","author":"Picavet","year":"2002","journal-title":"Am J Epidemiol"},{"issue":"16","key":"2020013005464968100_pnz093-B93","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1097\/BRS.0000000000001645","article-title":"Motor control exercise for nonspecific low back pain: A cochrane review","volume":"41","author":"Saragiotto","year":"2016","journal-title":"Spine"},{"issue":"22","key":"2020013005464968100_pnz093-B94","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1097\/BRS.0b013e3181e53334","article-title":"Poor back muscle endurance is related to pain catastrophizing in patients with chronic low back pain","volume":"35","author":"Larivi\u00e8re","year":"2010","journal-title":"Spine"},{"key":"2020013005464968100_pnz093-B95","article-title":"A clinical perspective on a pain neuroscience education approach to manual therapy","author":"Louw","journal-title":"J Man Manip Ther"}],"container-title":["Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/painmedicine\/article-pdf\/20\/12\/2571\/32290353\/pnz093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/painmedicine\/article-pdf\/20\/12\/2571\/32290353\/pnz093.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T05:47:49Z","timestamp":1580363269000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/painmedicine\/article\/20\/12\/2571\/5487811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,7]]},"references-count":95,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,5,7]]},"published-print":{"date-parts":[[2019,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/pm\/pnz093","relation":{},"ISSN":["1526-2375","1526-4637"],"issn-type":[{"value":"1526-2375","type":"print"},{"value":"1526-4637","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,12]]},"published":{"date-parts":[[2019,5,7]]}}}