{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T19:48:17Z","timestamp":1782416897618,"version":"3.54.5"},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Effective management of infectious disease relies not only on biomedical interventions but also on the circulation and interpretation of health-related information. Narratives, whether accurate or misleading, influence public perceptions, adherence to protective measures, and policy debates, as illustrated during COVID-19, measles resurgences, and vaccine controversies. YouTube, as a global platform combining an information repository and interactive discussion space, exerts persuasive influence through its audiovisual formats. Avian influenza, a recurrent zoonotic threat with episodic media attention, provides a valuable case for analyzing evolving health narratives. We analyzed 11,465 YouTube videos and associated comments related to avian influenza published between 2020 and 2025. Thematic structures were identified using an MPNet-based topic modeling approach, and sentiment analysis was conducted with XLM-RoBERTa to assess emotional tone across content and audience interactions. Temporal patterns of narrative clusters were also examined. Video content predominantly conveyed factual health information aligned with epidemiological updates and preventive measures. In contrast, user comments displayed substantial interpretive activity, including contestation, speculation, and the adoption of controversial frames concerning virus origins, institutional trust, public health interventions, and alternative treatments. These discussions were characterized by predominantly negative sentiment, indicating that audiences frequently recontextualize online information, potentially fostering ambiguity and misinformation. YouTube serves as both a disseminator of factual health information and a forum for audience reinterpretation, highlighting the platform's dual role in digital health communication. Understanding these dynamics is crucial for public health authorities seeking to design interventions that mitigate misinformation and promote effective protective behaviors during emerging infectious disease threats.<\/jats:p>","DOI":"10.1093\/pnasnexus\/pgag209","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:50:21Z","timestamp":1781077821000},"source":"Crossref","is-referenced-by-count":0,"title":["Health information dynamics and audience responses to avian influenza on YouTube: Implications for digital public health communication"],"prefix":"10.1093","volume":"5","author":[{"given":"Lisa","family":"Vors","sequence":"first","affiliation":[{"name":"CIRAD, UMR ASTRE, Montpellier, France, ASTRE, CIRAD, INRAE, Univ Montpellier , Montpellier, Universit\u00e9 de Toulouse, ENVT, Toulouse 31000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7245-7298","authenticated-orcid":false,"given":"Israa","family":"Farouk","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Calgary , Calgary , T2N 1N4","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3497-5404","authenticated-orcid":false,"given":"Paul","family":"Delon","sequence":"additional","affiliation":[{"name":"CIRAD, UMR ASTRE, Montpellier, France, ASTRE, CIRAD, INRAE, Univ Montpellier , Montpellier, Universit\u00e9 de Toulouse, ENVT, Toulouse 31000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Raboisson","sequence":"additional","affiliation":[{"name":"CIRAD, UMR ASTRE, Montpellier, France, ASTRE, CIRAD, INRAE, Univ Montpellier , Montpellier, Universit\u00e9 de Toulouse, ENVT, Toulouse 31000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5529-6572","authenticated-orcid":false,"given":"Jean-Christophe","family":"Boucher","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, University of Calgary , Calgary , T2N 1N4","place":["Canada"]},{"name":"Department of Political Science, Faculty of Arts, University of Calgary , Calgary , T2N 4V8","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2538-1586","authenticated-orcid":false,"given":"Guillaume","family":"Lhermie","sequence":"additional","affiliation":[{"name":"CIRAD, UMR ASTRE, Montpellier, France, ASTRE, CIRAD, INRAE, Univ Montpellier , Montpellier, Universit\u00e9 de Toulouse, ENVT, Toulouse 31000 ,","place":["France"]},{"name":"Faculty of Veterinary Medicine, University of Calgary , Calgary , T2N 1N4","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"2026062515164305600_pgag209-B1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/B978-0-12-801980-1.00010-6","volume-title":"Disasters and public health","author":"Clements","year":"2016"},{"key":"2026062515164305600_pgag209-B2","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1186\/s12889-019-7707-z","article-title":"What makes health systems resilient against infectious disease outbreaks and natural hazards? 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