{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T20:05:25Z","timestamp":1783973125891,"version":"3.55.0"},"reference-count":114,"publisher":"Oxford University Press (OUP)","issue":"1186","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2023xkj144"],"award-info":[{"award-number":["2023xkj144"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Health Research Project of Anhui Province","award":["AHWJ2023A30009"],"award-info":[{"award-number":["AHWJ2023A30009"]}]},{"name":"Applied Medical Research Project of Hefei Health Commission","award":["Hwk2021zd008"],"award-info":[{"award-number":["Hwk2021zd008"]}]},{"name":"Applied Medical Research Project of Hefei Health Commission","award":["Hwk2022zd013"],"award-info":[{"award-number":["Hwk2022zd013"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Fibrosis is a prevalent pathological condition observed in various organs and tissues. It primarily arises from the excessive and abnormal accumulation of the extracellular matrix, resulting in the structural and functional impairment of tissues and organs, which can culminate in death. Many forms of fibrosis, including liver, cardiac, pulmonary, and renal fibrosis, are considered irreversible. Maternally expressed gene 3 (MEG3) is an imprinted RNA gene. Historically, the downregulation of MEG3 has been linked to tumor pathogenesis. However, recent studies indicate an emerging association of MEG3 with fibrotic diseases. In this review, we delve into the current understanding of MEG3\u2019s role in fibrosis, aiming to shed light on the molecular mechanisms of fibrosis and the potential of MEG3 as a novel therapeutic target.<\/jats:p>","DOI":"10.1093\/postmj\/qgad124","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T13:13:52Z","timestamp":1709385232000},"page":"529-538","source":"Crossref","is-referenced-by-count":5,"title":["The role of long noncoding RNA MEG3 in fibrosis diseases"],"prefix":"10.1093","volume":"100","author":[{"given":"Wenlong","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine , , Hefei 230022 , China"},{"name":"The First Afiliated Hospital of Anhui Medical University , , Hefei 230022 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Occupational Disease , , Hefei 230022 , China"},{"name":"Hefei Third Clinical College of Anhui Medical University , , Hefei 230022 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghe","family":"Fei","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine , , Hefei 230022 , China"},{"name":"The First Afiliated Hospital of Anhui Medical University , , Hefei 230022 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine , , Hefei 230022 , China"},{"name":"The First Afiliated Hospital of Anhui Medical University , , Hefei 230022 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,1]]},"reference":[{"key":"2024072206551546300_ref1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1172\/JCI93563","article-title":"Resolution of organ 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