{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T22:35:39Z","timestamp":1773873339324,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1187","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cutaneous leishmaniasis (CL) is most common in childhood because children are exposed to the parasite early and, unlike adults, do not have immunity to CL. Since CL is less common in geriatric patients, clinical and epidemiological data in this age group are limited. This study aims to compare the clinical and demographic characteristics of geriatric patients diagnosed with CL with young patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In this retrospective study, 622 patients aged 65 and over and 6350 patients aged 19\u201364, who applied to \u015eanl\u0131urfa Oriental Boil Diagnosis and Treatment Center between January 2013 and February 2024 and were diagnosed with CL by parasitological examination, were included. Clinical and demographic characteristics of patients diagnosed with CL, such as age, gender, location of the lesion, lesion size, duration of the lesion, and treatments applied due to the diagnosis of CL, were recorded. Clinical and demographic characteristics of geriatric and young patients were compared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean age of elderly CL cases was 72.95\u2009\u00b1\u20096.54\u00a0years, and 65.2% were female. The most common clinical forms were ulcers (51.9%) and plaques (41%), respectively, in young and elderly patients. The most common locations of the lesions were upper limbs (54.8%) in all patients. The most preferred treatment method was intralesional (IL) meglumine antimoniate (MA) treatment (98.3%) in all patients. There were no difference between young and elderly CL cases in terms of mean number of lesions, average lesion duration, average lesion size, lesion location, clinical forms of lesions, and treatments options (P\u2009&amp;gt;\u20090.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Based on the results of our study, it can be said that the clinical and demographic characteristics of CL are similar in young and old patients and systemic MA treatment shows similar clinical benefit in both age groups. In addition, it can be said that systemic MA therapy can be used safely in young patients and elderly patients without contraindications. IL MA therapy can be used in elderly patients where systemic MA therapy is contraindicated.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/postmj\/qgae048","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T21:56:46Z","timestamp":1712786206000},"page":"666-670","source":"Crossref","is-referenced-by-count":3,"title":["Geriatric cutaneous leishmaniasis: a retrospective analysis of 622 cases"],"prefix":"10.1093","volume":"100","author":[{"given":"Nebiye Yentur","family":"Doni","sequence":"first","affiliation":[{"name":"Harran University Medical Faculty Department of Medical Microbiology, , \u015eanl\u0131urfa 63000, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130sa","family":"An","sequence":"additional","affiliation":[{"name":"\u015eanl\u0131urfa Training and Research Hospital Department of Dermatology, , \u015eanl\u0131urfa 63000, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,10]]},"reference":[{"key":"2024081911461701000_ref1","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s40257-022-00726-8","article-title":"Cutaneous leishmaniasis: a 2022 updated narrative review into diagnosis and management developments","volume":"23","author":"de Vries","year":"2022","journal-title":"Am J Clin Dermatol"},{"key":"2024081911461701000_ref2","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1111\/ijd.14002","article-title":"Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey","volume":"57","author":"Uzun","year":"2018","journal-title":"Int J Dermatol"},{"key":"2024081911461701000_ref3","doi-asserted-by":"crossref","first-page":"e13730","DOI":"10.1111\/ijcp.13730","article-title":"Atypical and unusual morphological variants of cutaneous 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