{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T16:37:58Z","timestamp":1770827878001,"version":"3.50.1"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"1201","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Central Health Research","award":["2020ZD10"],"award-info":[{"award-number":["2020ZD10"]}]},{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"publisher","award":["2022YFC2010103"],"award-info":[{"award-number":["2022YFC2010103"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Alzheimer\u2019s disease, the most prevalent cause of dementia, is a worldwide health problem. Proteomics is the systematic study of proteins and peptides to provide comprehensive descriptions. Aiming to obtain a more accurate and convenient clinical diagnosis, researchers are working on blood biomarkers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>This review synthesizes findings from previous studies investigating blood biomarkers for Alzheimer\u2019s disease using proteomic approaches.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We summarized the application of blood proteomics as diagnostic biomarkers and associations with clinical indicators such as neuropsychological performances, A\u03b2 deposition and brain atrophy in Alzheimer\u2019s disease, and mild cognitive impairment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In summary, blood proteomics is suggested to be promising in biomarkers of Alzheimer\u2019s disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/postmj\/qgaf039","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T08:22:57Z","timestamp":1742199777000},"page":"1103-1114","source":"Crossref","is-referenced-by-count":1,"title":["Blood biomarkers of Alzheimer\u2019s disease: findings from proteomics"],"prefix":"10.1093","volume":"101","author":[{"given":"Yuye","family":"Wang","sequence":"first","affiliation":[{"name":"Department of neurology, China-Japan Friendship Hospital , No. 2 Yinghua East Street, Chaoyang district, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqian","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of neurology, Xijing Hospital, Fourth Military Medical University , No. 127 Changle West Road, Xi'an, Shaanxi 710032 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weizhe","family":"Zhen","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine , No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[{"name":"China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College , No. 2 Yinghua East Street, Chaoyang district, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leian","family":"Chen","sequence":"additional","affiliation":[{"name":"China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College , No. 2 Yinghua East Street, Chaoyang district, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuchen","family":"Liu","sequence":"additional","affiliation":[{"name":"China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College , No. 2 Yinghua East Street, Chaoyang district, Beijing 100029 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"Core Facility of Instrument, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College , No. 5 Dong Dan San Tiao, Dongcheng District, Beijing 100005 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dantao","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of neurology, China-Japan Friendship Hospital , No. 2 Yinghua East Street, Chaoyang district, Beijing 100029 ,","place":["China"]},{"name":"China-Japan Friendship Hospital, 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