{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:44:32Z","timestamp":1792683872897,"version":"4.5.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1213","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Osteoporosis (OP) and aromatase inhibitor (AI)-induced bone loss are major concerns among postmenopausal women with breast cancer. This study aimed to comparatively evaluate guideline-concordant bone health management for OP and AI-induced bone loss across two tertiary centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed medical records of 2224 postmenopausal women with breast cancer. Demographic characteristics, comorbidities, medication use, and baseline bone mineral density (BMD) and T-score values were extracted for all patients screened or followed between 2019 and 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 2224 women, AI use at the time of DXA assessment (N\u2009=\u20091146) was more frequent in Center 2 than Center 1 (79.4% vs. 35.6%, P\u2009&amp;lt;\u2009.001). Among AI users, OP prevalence was similar between centers (Center 1: 25.0%; Center 2: 26.2%); however, anti-osteoporotic treatment prescribing was higher in Center 2 (85.7% vs. 49.2%, P\u2009&amp;lt;\u2009.001). Among treatment-indicated non-osteoporotic AI users according to European Society of Medical Oncology guideline, prescribing rates were also higher in Center 2 (85.1% vs. 23.0%, P\u2009&amp;lt;\u2009.001). Among osteoporotic AI nonusers, treatment rates remained higher in Center 2 (75.9% vs. 45.8%, P\u2009&amp;lt;\u2009.001). Binary logistic regression confirmed center type as an independent predictor of treatment prescribing (OR: 9.414, 95% confidence interval: 6.669\u201313.289, P\u2009&amp;lt;\u2009.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Guideline-concordant prescribing for AI-induced bone loss differed substantially between the two centers. Prospective studies evaluating longitudinal BMD changes, fracture outcomes, and treatment persistence are warranted to determine the clinical impact of these differences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/postmj\/qgag098","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:52:22Z","timestamp":1783511542000},"page":"1030-1036","source":"Crossref","is-referenced-by-count":0,"title":["Guideline adherence in the management of aromatase inhibitor-induced bone loss in women with breast cancer"],"prefix":"10.1093","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2884-6994","authenticated-orcid":false,"given":"Pelin","family":"Menemencio\u011flu","sequence":"first","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Kara","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice G\u00fclg\u00fcn","family":"F\u0131rat","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Abdurrahman Yurtaslan Oncology Training and Research Hospital , Yenimahalle, 06200 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4034-1558","authenticated-orcid":false,"given":"Ahmet Furkan","family":"\u00c7olak","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahya","family":"Demirler","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmud Faz\u0131l","family":"Aksakal","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Ocak","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilmi Berkan","family":"Abac\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6069-4575","authenticated-orcid":false,"given":"Berkay","family":"Yal\u00e7\u0131nkaya","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Toprak","sequence":"additional","affiliation":[{"name":"Department of Pain Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara 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\u0130rem","family":"Kara","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Abdurrahman Yurtaslan Oncology Training and Research Hospital , Yenimahalle, 06200 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zg\u00fcr","family":"Kara","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Abdurrahman Yurtaslan Oncology Training and Research Hospital , Yenimahalle, 06200 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bayram","family":"Kaymak","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Hacettepe University Medical School , Alt\u0131nda\u011f, 06230 Ankara ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zt\u00fcrk","family":"Ate\u015f","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Abdurrahman 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