{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:06:40Z","timestamp":1780704400282,"version":"3.54.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T00:00:00Z","timestamp":1571270400000},"content-version":"vor","delay-in-days":6985,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2000,9]]},"DOI":"10.1093\/ps\/79.9.1345","type":"journal-article","created":{"date-parts":[[2014,2,6]],"date-time":"2014-02-06T19:31:19Z","timestamp":1391715079000},"page":"1345-1350","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Effect of in ovo administration of insulin-like growth factor-I on compositionand mechanical properties of chicken bone"],"prefix":"10.1016","volume":"79","author":[{"given":"H.","family":"Kocamis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.N.","family":"Yeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.U.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.B.","family":"Kenney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.C.","family":"Kirkpatrick-Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Killefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ps\/79.9.1345_bib484","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0955-2235(96)00011-7","article-title":"Conservation of IGFBP structure during evolution: Cloning of chicken insulin-like growth factor binding protein-5","volume":"6","author":"Allander","year":"1995","journal-title":"Prog. Growth Factor Res."},{"key":"10.1093\/ps\/79.9.1345_bib485","volume":"8.01","year":"1990"},{"key":"10.1093\/ps\/79.9.1345_bib486","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0092-8674(05)80085-6","article-title":"Role of insulin-like growth factors in embryonic and postnatal growth","volume":"75","author":"Baker","year":"1993","journal-title":"Cell"},{"key":"10.1093\/ps\/79.9.1345_bib487","doi-asserted-by":"crossref","first-page":"637","DOI":"10.2337\/diab.37.5.637","article-title":"Developmental regulation of insulin and type I IGF receptor and absence of type II receptors in chicken embryo tissues","volume":"37","author":"Bassas","year":"1988","journal-title":"Diabetes"},{"key":"10.1093\/ps\/79.9.1345_bib488","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0739-7240(88)90033-1","article-title":"Recombinant bovine somatotropin stimulates short term increases in growth rate and IGF-I in chickens","volume":"5","author":"Buonomo","year":"1988","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib489","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1172\/JCI109908","article-title":"Effect of insulin-like growth factor-I on DNA and protein synthesis in cultured rat calvaria","volume":"66","author":"Canalis","year":"1980","journal-title":"J. Clin. Invest."},{"key":"10.1093\/ps\/79.9.1345_bib490","doi-asserted-by":"crossref","first-page":"620","DOI":"10.3382\/ps.0630620","article-title":"Leg deformities: Inability to increase severity by increasing body weight of chicks and poults","volume":"63","author":"Cook","year":"1984","journal-title":"Poultry Sci."},{"key":"10.1093\/ps\/79.9.1345_bib491","first-page":"49","article-title":"Additive effects on body growth of insulin-like growth factor-I and growth hormone in hypophysectomized rats","volume":"1","author":"Clark","year":"1994","journal-title":"Endocrinol. Metab."},{"key":"10.1093\/ps\/79.9.1345_bib492","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0092-8674(89)90281-X","article-title":"Signal transmission by the IGFs","volume":"59","author":"Czech","year":"1989","journal-title":"Cell"},{"key":"10.1093\/ps\/79.9.1345_bib493","series-title":"Growth hormone and the somatomedins. Pages 1\u201324 in: Endocrine Control of Growth","author":"Daughaday","year":"1981"},{"key":"10.1093\/ps\/79.9.1345_bib494","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1677\/joe.0.1280035","article-title":"Stimulation of DNA synthesis in chicken muscle satellite cells by insulin and insulin-like growth factors: Evidence for exclusive mediation by type I IGF receptor","volume":"128","author":"Duclos","year":"1991","journal-title":"J. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib495","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/S0006-291X(88)80466-2","article-title":"Isolation and characterization of insulin-like growth factor-II from human bone","volume":"151","author":"Frolik","year":"1988","journal-title":"Biochem. Biophys. Res. Comm."},{"key":"10.1093\/ps\/79.9.1345_bib496","series-title":"Mechanics of Materials","author":"Gere","year":"1990"},{"key":"10.1093\/ps\/79.9.1345_bib497","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1432-0436.1985.tb00316.x","article-title":"A dual effector theory of growth-hormone action","volume":"29","author":"Green","year":"1985","journal-title":"Differentiation"},{"key":"10.1093\/ps\/79.9.1345_bib498","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1126\/science.3726546","article-title":"The generation of insulin-like growth factor-1 sensitive cells by growth hormone action","volume":"233","author":"Green","year":"1986","journal-title":"Science"},{"key":"10.1093\/ps\/79.9.1345_bib499","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.1073\/pnas.85.13.4889","article-title":"Recombinant human insulin-like growth factor-I stimulates growth and has distinct effects on organ size in hypophyzectomized rats","volume":"85","author":"Guler","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1093\/ps\/79.9.1345_bib500","doi-asserted-by":"crossref","first-page":"745","DOI":"10.3382\/ps.0580745","article-title":"Plasma growth hormone levels in normal and testosterone implanted growing chickens","volume":"58","author":"Harvey","year":"1979","journal-title":"Poultry Sci."},{"key":"10.1093\/ps\/79.9.1345_bib501","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1677\/joe.0.0890275","article-title":"Effect of bovine growth hormone and a partially pure preparation of somatomedin on various growth parameters in hypopituitary dwarf mice","volume":"89","author":"Holder","year":"1981","journal-title":"J. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib502","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1210\/edrv-8-4-426","article-title":"Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth","volume":"8","author":"Isaksson","year":"1987","journal-title":"Endocrin Rev."},{"key":"10.1093\/ps\/79.9.1345_bib503","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1210\/endo-128-3-1323","article-title":"Expression of insulin-like growth factor-I during chicken development","volume":"128","author":"Kikuchi","year":"1991","journal-title":"Endocrinology"},{"key":"10.1093\/ps\/79.9.1345_bib504","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1093\/ps\/77.12.1913","article-title":"In ovo administration of recombinant human insulin-like growth factor-I alters postnatal growth and development of the broiler chicken","volume":"77","author":"Kocamis","year":"1998","journal-title":"Poultry Sci."},{"key":"10.1093\/ps\/79.9.1345_bib505","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1093\/ps\/78.8.1219","article-title":"Postnatal growth of broilers in response to in ovo administration of chicken growth hormone","volume":"78","author":"Kocamis","year":"1999","journal-title":"Poultry Sci."},{"issue":"Suppl. 1","key":"10.1093\/ps\/79.9.1345_bib506","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0021-9290(91)90379-2","article-title":"Determinants of the mechanical properties of bones","volume":"24","author":"Martin","year":"1991","journal-title":"J. Biomechanics"},{"key":"10.1093\/ps\/79.9.1345_bib507","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/8756-3282(96)00072-5","article-title":"Pyridoxine deficiency affects biomechanical properties of chick tibial bone","volume":"18","author":"Masse","year":"1996","journal-title":"Bone"},{"key":"10.1093\/ps\/79.9.1345_bib508","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM198602133140702","article-title":"Relation between complications of type I diabetes mellitus and collagen-linked fluorescence","volume":"314","author":"Monnier","year":"1986","journal-title":"N. Eng. J. Med."},{"key":"10.1093\/ps\/79.9.1345_bib509","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/j.1751-0813.1972.tb09237.x","article-title":"Leg weakness of poultry\u2014A clinical and pathalogical characterization","volume":"48","author":"Narin","year":"1972","journal-title":"Aust. Vet. J."},{"key":"10.1093\/ps\/79.9.1345_bib510","first-page":"1","article-title":"Clonal analysis rat tibia growth plate chodrocytes in suspension culture-differential effects of growth hormone and insulin-like growth factor-I","volume":"4","author":"Ohlsson","year":"1994","journal-title":"Growth Regul."},{"key":"10.1093\/ps\/79.9.1345_bib511","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1006\/gcen.1994.1082","article-title":"Regulation of cell proliferation and estrogen synthesis by ovine LH. IGF-I and EGF in theca interstitial cells of domestic hen cultured in defined media","volume":"94","author":"Onagbesan","year":"1994","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib512","doi-asserted-by":"crossref","first-page":"3721","DOI":"10.1210\/endo.136.9.7649077","article-title":"Evidence that somatotroph differentiation during chicken embryonic development is stimulated by a blood-borne signal","volume":"136","author":"Porter","year":"1995","journal-title":"Endocrinology"},{"key":"10.1093\/ps\/79.9.1345_bib513","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1101\/gad.7.12b.2609","article-title":"IGF-I is required for normal embryonic growth in mice","volume":"7","author":"Powell-Braxton,","year":"1993","journal-title":"Genes Dev."},{"key":"10.1093\/ps\/79.9.1345_bib514","doi-asserted-by":"crossref","first-page":"308","DOI":"10.3382\/ps.0590308","article-title":"Curled toes and perosis-like leg abnormalities in cage reared broilers","volume":"59","author":"Rizk","year":"1980","journal-title":"Poultry Sci."},{"key":"10.1093\/ps\/79.9.1345_bib515","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1006\/gcen.1994.1037","article-title":"IGF-I in the ovary of laying hen: Gene expression and biological actions on granulosa and thecal cells","volume":"93","author":"Roberts","year":"1994","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib516","series-title":"Version 6","year":"1989"},{"key":"10.1093\/ps\/79.9.1345_bib517","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1006\/gcen.1997.6876","article-title":"Ontogenic changes in the circulating concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGF-binding proteins in the chicken embryo","volume":"106","author":"Scanes","year":"1997","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib518","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.3382\/ps.0701764","article-title":"Growth hormone and insulin-like growth factors in poultry growth: Required, optimal or ineffective?","volume":"70","author":"Scanes","year":"1991","journal-title":"Poultry Sci."},{"key":"10.1093\/ps\/79.9.1345_bib519","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1677\/jme.0.0150049","article-title":"Cloning and characterization of a chick embryo cDNA and gene for IGFBP-2","volume":"15","author":"Schoen","year":"1995","journal-title":"J. Mol. Endocrinol."},{"key":"10.1093\/ps\/79.9.1345_bib520","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/BF00298748","article-title":"Effect of decalcification on bone mineral content and bending strength of feline femur","volume":"56","author":"Shah","year":"1995","journal-title":"Calcif. Tissue Int."},{"key":"10.1093\/ps\/79.9.1345_bib521","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1210\/endo.137.1.8536628","article-title":"Growth hormone independent expression of IGF-I messenger RNA in extrahepatic tissues of chicken","volume":"137","author":"Tanaka","year":"1996","journal-title":"Endocrinology"},{"key":"10.1093\/ps\/79.9.1345_bib522","series-title":"The somatomedins: Biological actions and physiological control mechanism. Pages 82\u2013125 in: Hormonal Proteins and Peptides","author":"Van Wyk,","year":"1984"},{"key":"10.1093\/ps\/79.9.1345_bib523","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/0016-6480(88)90255-9","article-title":"Effect of pattern of administration on the response to exogenous, pituitary-derived chicken growth hormone by broiler-strain pullets","volume":"71","author":"Vasilatos-Younken,","year":"1988","journal-title":"Gen. Comp. Endocrinol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119416337?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119416337?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ps\/article-pdf\/79\/9\/1345\/4492290\/poultrysci79-1345.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T21:26:16Z","timestamp":1758489976000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579119416337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["S0032579119416337"],"URL":"https:\/\/doi.org\/10.1093\/ps\/79.9.1345","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2000,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of in ovo administration of insulin-like growth factor-I on compositionand mechanical properties of chicken bone","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ps\/79.9.1345","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Poultry Science Association Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}