{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:58:23Z","timestamp":1755601103441,"version":"3.37.3"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T00:00:00Z","timestamp":1589328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000005","name":"Department of Defense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Department of Veterans Affairs Joint Incentive Fund"},{"name":"Miami Veterans Affairs Healthcare System"},{"name":"Henry Jackson Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The modified Clinical Test of Sensory Interaction and Balance (mCTSIB) is used to clinically assess vestibular sensory integration (VSI), the process by which the central nervous system integrates vestibular afference to maintain balance. The rate and effects of impaired VSI (IVSI) on prosthetic mobility in people with lower limb amputation (LLA) is unknown. The objective of this study was to use the mCTSIB to classify VSI in active community ambulators with LLA and to examine the relationship between IVSI and prosthetic mobility, as measured by the Component Timed Up and Go (cTUG) test.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a cross-sectional study with a convenience sample of 130 community ambulators with unilateral LLA. Classification of VSI was determined based on a time-based pass\/fail mCTSIB performance. Participants were classified as having normal sensory integration (NSI) if they could balance for 30\u00a0seconds in every mCTSIB condition. Participants who failed condition 4 exclusively were classified as IVSI. Prosthetic mobility, as measured by the cTUG, was compared between NSI and IVSI groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 130 participants, 29 (22%) were classified as IVSI and 95 (73%) were classified as having NSI. Prosthetic mobility significantly differed between IVSI and NSI groups, with IVSI participants performing all components of the cTUG significantly slower. Medium to large effect sizes were found between groups during cTUG.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>These results suggest that 1 in 5 community ambulators with LLA have IVSI, with associated limitations in balance confidence and prosthetic mobility.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Impact<\/jats:title>\n                  <jats:p>The ability to integrate vestibular information was found to have a strong relationship with prosthetic mobility in active community ambulators with LLA, especially with performing a 180-degree step turn. Physical therapists can use the mCTSIB to classify sensory integration during prosthetic rehabilitation and develop an appropriate balance intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Lay Summary<\/jats:title>\n                  <jats:p>Active adults with LLA can use information from their senses to maintain their standing balance. Adults with LLA who have difficulty balancing on foam with closed eyes were slower to get in and out of a chair, walk, and perform a 180-degree step turn.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzaa091","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T19:17:41Z","timestamp":1588706261000},"page":"1333-1342","source":"Crossref","is-referenced-by-count":5,"title":["The Relationship Between Vestibular Sensory Integration and Prosthetic Mobility in Community Ambulators With Unilateral Lower Limb Amputation"],"prefix":"10.1093","volume":"100","author":[{"given":"Jennifer","family":"Lu\u010darevi\u0107","sequence":"first","affiliation":[{"name":"Department of Physical Therapy , , , Coral Gables, Florida; and , Department of Orthotics and Prosthetics, Carson, California"},{"name":"Miller School of Medicine , , , Coral Gables, Florida; and , Department of Orthotics and Prosthetics, Carson, California"},{"name":"University of Miami , , , Coral Gables, Florida; and , Department of Orthotics and Prosthetics, Carson, California"},{"name":"California State University Dominguez Hills , , , Coral Gables, Florida; and , Department of Orthotics and Prosthetics, Carson, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Gaunaurd","sequence":"additional","affiliation":[{"name":"Miami Veterans Affairs Healthcare System , Miami, Florida; and Department of Physical Therapy, Miller School of Medicine, University of Miami"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Clemens","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of Miami; and , Florida International University, Miami, Florida"},{"name":"Miller School of Medicine , , University of Miami; and , Florida International University, Miami, Florida"},{"name":"Department of Physical Therapy , , University of Miami; and , Florida International University, Miami, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulina","family":"Belsky","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of Miami"},{"name":"Miller School of Medicine , , University of Miami"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Summerton","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of Miami"},{"name":"Miller School of Medicine , , University of Miami"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melody","family":"Walkup","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of Miami"},{"name":"Miller School of Medicine , , University of Miami"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen Paden","family":"Wallace","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of 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C","family":"Schubert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head Surgery , , Baltimore, Maryland"},{"name":"The Johns Hopkins University School of Medicine , , Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S","family":"Gailey","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy , , University of Miami, 5915 Ponce de Leon Boulevard, Coral Gables, FL 33146 ( USA )"},{"name":"Miller School of Medicine , , University of Miami, 5915 Ponce de Leon Boulevard, Coral Gables, FL 33146 ( USA )"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,5,13]]},"reference":[{"key":"2023011901095224500_ref1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3109\/03093640903585008","article-title":"Impairment variables predicting activity limitation in individuals with lower limb 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