{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:13:46Z","timestamp":1789020826670,"version":"build-2803163510"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T00:00:00Z","timestamp":1616198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Care Sciences at Karolinska Institutet, Stockholm, Sweden"},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The aim of this study was to investigate if mobilization out of bed, within 2\u00a0hours after abdominal surgery, improved participants\u2019 respiratory function and whether breathing exercises had an additional positive effect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Participants were 214 consecutively recruited patients who underwent elective open or robot-assisted laparoscopic gynecological, urological, or endocrinological abdominal surgery with an anesthetic duration of &amp;gt;2\u00a0hours. They were recruited to a randomized controlled trial. Immediately after surgery, patients were randomly assigned to 1 of 3 groups: mobilization (to sit in a chair) and standardized breathing exercises (n\u00a0=\u00a073), mobilization (to sit in a chair) only (n\u00a0=\u00a076), or control (n\u00a0=\u00a065). The interventions started within 2\u00a0hours after arrival at the postoperative recovery unit and continued for a maximum of 6\u00a0hours. The primary outcomes were differences in peripheral oxygen saturation (SpO2, as a percentage) and arterial oxygen pressure (PaO2, measured in kilopascals) between the groups. Secondary outcomes were arterial carbon dioxide pressure, spirometry, respiratory insufficiency, pneumonia, and length of stay.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Based on intention-to-treat analysis (n\u00a0=\u00a0214), patients who received mobilization and breathing exercises had significantly improved SpO2 (mean difference [MD]\u00a0=\u00a02.5%; 95% CI\u00a0=\u00a00.4 to 4.6) and PaO2 (MD\u00a0=\u00a01.40\u00a0kPa; 95% CI\u00a0=\u00a00.64 to 2.17) compared with the controls. For mobilization only, there was an increase in PaO2 (MD\u00a0=\u00a00.97\u00a0kPa; 95% CI\u00a0=\u00a00.20 to 1.74) compared with the controls. In the per-protocol analysis (n\u00a0=\u00a0201), there were significant improvements in SpO2 and PaO2 for both groups receiving mobilization compared with the controls. Secondary outcome measures did not differ between groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Mobilization out of bed, with or without breathing exercises, within 2\u00a0hours after elective abdominal surgery improved SpO2 and PaO2.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Impact<\/jats:title>\n                  <jats:p>The respiratory effect of mobilization (out of bed) immediately after surgery has not been thoroughly evaluated in the literature. This study shows that mobilization out of bed following elective abdominal surgery can improve SpO2 and PaO2.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Lay Summary<\/jats:title>\n                  <jats:p>Mobilization within 2\u00a0hours after elective abdominal surgery, with or without breathing exercises, can improve patients\u2019 respiratory function.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzab094","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T04:13:17Z","timestamp":1615954397000},"source":"Crossref","is-referenced-by-count":50,"title":["Mobilization Started Within 2\u00a0Hours After Abdominal Surgery Improves Peripheral and Arterial Oxygenation: A Single-Center Randomized Controlled Trial"],"prefix":"10.1093","volume":"101","author":[{"given":"Anna","family":"Svensson-Raskh","sequence":"first","affiliation":[{"name":"Department of Neurobiology , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"},{"name":"Karolinska Institutet , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"},{"name":"Women\u2019s Health and Allied Health Professionals Theme , Medical Unit Occupational Therapy and Physiotherapy, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Regina","family":"Schandl","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery, Karolinska Institutet , Stockholm, Sweden"},{"name":"Department of Anesthesia and Intensive Care , S\u00f6dersjukhuset, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agneta","family":"St\u00e5hle","sequence":"additional","affiliation":[{"name":"Department of Neurobiology , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"},{"name":"Karolinska Institutet , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malin","family":"Nygren-Bonnier","sequence":"additional","affiliation":[{"name":"Department of Neurobiology , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"},{"name":"Karolinska Institutet , Care Sciences and Society, Division of Physiotherapy, , Stockholm, Sweden"},{"name":"Women\u2019s Health and Allied Health Professionals Theme , Medical Unit Occupational Therapy and Physiotherapy, Karolinska University Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Fagevik Ols\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Neuroscience and Physiology , Division of Health & Rehabilitation\/Physical Therapy, Sahlgrenska Academy, , Gothenburg, Sweden"},{"name":"Gothenburg University , Division of Health & Rehabilitation\/Physical Therapy, Sahlgrenska Academy, , Gothenburg, 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