{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:30:59Z","timestamp":1762918259894,"version":"3.41.2"},"reference-count":75,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The main aims of this study were to (1) create a patient-reported outcome measure (PROM) item bank for measuring the impact of upper quadrant edema (UQE) on physical function by calibrating responses to newly developed items; and (2) assess reliability, validity, and administration efficiency of scores based on computerized adaptive test (CAT) and 10-item short-form (SF) administration modes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a retrospective study including data from patients treated in outpatient rehabilitation clinics for UQE that responded to all 27 candidate items at intake. Item response theory model assumptions of unidimensionality, local item independence, item fit, and presence of differential item functioning were evaluated. UQE-CAT\u2013 and UQE-SF\u2013generated scores were assessed for reliability, validity, and administration efficiency.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The total cohort included 3486 patients (mean [SD] age\u2009=\u200961 [13] years; range\u2009=\u200914\u201389 years). After removing 2 items, a 25-item solution was supported for its unidimensionality and fit to the item response theory model with reliability estimates of more than 0.93 for scores based on both CAT and SF administration modes. No items demonstrated differential item functioning. Scores discriminated among multiple patient groups in clinically logical ways and were moderately responsive to change with negligible floor and acceptable ceiling effects. CAT scores were generated using an average of 5.6 items (median\u2009=\u20095).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Scores on the UQE PROM were reliable, valid, and efficient for assessing perceived physical function of patients with upper quadrant edema; thus, the measure is suitable for research and routine clinical administration.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Impact<\/jats:title>\n                  <jats:p>The newly developed UQE PROM is reliable and valid and offers efficient administration modes for assessing perceived physical function of patients with UQE caused by lymphatic and venous disorders, both for research and routine clinical care in busy outpatient rehabilitation settings. As an item response theory\u2013based measure, the UQE PROM allows administration of condition-specific functional questions with low response burden for patients. This study supports a transition to PROMs that are based on modern measurement approaches to achieve high accuracy and efficiency.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzab219","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T19:14:45Z","timestamp":1632251685000},"source":"Crossref","is-referenced-by-count":6,"title":["Upper Quadrant Edema Patient-Reported Outcome Measure Is Reliable, Valid, and Efficient for Patients With Lymphatic and Venous Disorders"],"prefix":"10.1093","volume":"101","author":[{"given":"Daniel","family":"Deutscher","sequence":"first","affiliation":[{"name":"Net Health Systems, Inc, Pittsburgh, Pennsylvania, USA"},{"name":"Maccabitech Institute for Research & Innovation, Maccabi Healthcare Services, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deanna","family":"Hayes","sequence":"additional","affiliation":[{"name":"Net Health Systems, Inc, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karon F","family":"Cook","sequence":"additional","affiliation":[{"name":"FeralScholars, Broaddus, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark W","family":"Werneke","sequence":"additional","affiliation":[{"name":"Net Health Systems, Inc, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carole A","family":"Tucker","sequence":"additional","affiliation":[{"name":"Department of Health and Rehabilitation Sciences, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome E","family":"Mioduski","sequence":"additional","affiliation":[{"name":"Net Health Systems, Inc, Pittsburgh, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Levenhagen","sequence":"additional","affiliation":[{"name":"Program in Physical Therapy, Saint Louis University, Saint Louis, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorit","family":"Tidhar","sequence":"additional","affiliation":[{"name":"Physical Therapy Department, Maccabi Healthcare Services, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Pfarr","sequence":"additional","affiliation":[{"name":"HSHS Wisconsin & Prevea Health, Green Bay, Wisconsin, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A","family":"Kallen","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"2021123116352214500_ref1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.21037\/gs.2017.11.04","article-title":"Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments","volume":"7","author":"Gillespie","year":"2018","journal-title":"Gland Surg"},{"key":"2021123116352214500_ref2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s11764-010-0118-x","article-title":"Upper extremity impairments in women with or without lymphedema following breast cancer treatment","volume":"4","author":"Smoot","year":"2010","journal-title":"J Cancer Surviv"},{"key":"2021123116352214500_ref3","first-page":"3","article-title":"The diagnosis and treatment of peripheral lymphedema: 2020 consensus document of the International Society of Lymphology","volume":"53","author":"Executive Committee of the International Society of Lymphology","year":"2020","journal-title":"Lymphology"},{"key":"2021123116352214500_ref4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jamasurg.2020.0230","article-title":"Quality-of-life outcomes in surgical vs nonsurgical treatment of breast cancer-related lymphedema: a systematic review","volume":"155","author":"Fish","year":"2020","journal-title":"JAMA Surg"},{"key":"2021123116352214500_ref5","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1089\/lrb.2016.0049","article-title":"Does lymphedema severity affect quality of life? 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