{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:47:15Z","timestamp":1790113635523,"version":"4.0.1"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Istituto Nazionale Assicurazione Infortuni sul Lavoro"},{"name":"Sant\u2019Anna School of Advanced Studies\u2014Pisa"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>People with transfemoral amputation have balance and mobility problems and are at high risk of falling. An adequate prosthetic prescription is essential to maximize their functional levels and enhance their quality of life. This study aimed to evaluate the degree of safety against falls offered by different prosthetic knees.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective study was conducted using data from a center for prosthetic fitting and rehabilitation. Eligible individuals were adults with unilateral transfemoral amputation or knee disarticulation. The prosthetic knee models were grouped into 4 categories: locked knees, articulating mechanical knees (AMKs), fluid-controlled knees (FK), and microprocessor-controlled knees (MPK). The outcome was the number of falls experienced during inpatient rehabilitation while wearing the prosthesis. Association analyses were performed with mixed-effect Poisson models. Propensity score weighting was used to adjust causal estimates for participant confounding factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Data on 1486 hospitalizations of 815 individuals were analyzed. Most hospitalizations (77.4%) were related to individuals with amputation due to trauma. After propensity score weighting, the knee category was significantly associated with falls. People with FK had the highest rate of falling (incidence rate\u2009=\u20092.81 falls per 1000 patient days, 95% CI\u2009=\u20091.96 to 4.02). FK significantly increased the risk of falling compared with MPK (incidence rate ratio [IRRFK-MPK]\u2009=\u20092.44, 95% CI\u2009=\u20091.20 to 4.96). No other comparison among knee categories was significant.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Fluid-controlled prosthetic knees expose inpatients with transfemoral amputation to higher incidence of falling than MPK during rehabilitation training.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Impact<\/jats:title>\n                  <jats:p>These findings can guide clinicians in the selection of safe prostheses and reduction of falls in people with transfemoral amputation during inpatient rehabilitation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzab310","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T20:09:30Z","timestamp":1641586170000},"source":"Crossref","is-referenced-by-count":13,"title":["Degree of Safety Against Falls Provided by 4 Different Prosthetic Knee Types in People With Transfemoral Amputation: A Retrospective Observational Study"],"prefix":"10.1093","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4438-1787","authenticated-orcid":false,"given":"Pierpaolo","family":"Palumbo","sequence":"first","affiliation":[{"name":"Department of Electrical , Electronic, and Information Engineering \u201cGuglielmo Marconi,\u201d Alma Mater Studiorum University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pericle","family":"Randi","sequence":"additional","affiliation":[{"name":"Unit\u00e0 operativa di medicina fisica e riabilitazione , INAIL Centro Protesti, Vigoroso di Budrio, Emilia-Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0538-650X","authenticated-orcid":false,"given":"Serena","family":"Moscato","sequence":"additional","affiliation":[{"name":"Department of Electrical , Electronic, and Information Engineering \u201cGuglielmo Marconi,\u201d Alma Mater Studiorum University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5007-8661","authenticated-orcid":false,"given":"Angelo","family":"Davalli","sequence":"additional","affiliation":[{"name":"Area ricerca e formazione , INAIL Centro Protesti, Vigoroso di Budrio, Emilia-Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2318-4370","authenticated-orcid":false,"given":"Lorenzo","family":"Chiari","sequence":"additional","affiliation":[{"name":"Department of Electrical , Electronic, and Information Engineering \u201cGuglielmo Marconi,\u201d Alma Mater Studiorum University of Bologna, Bologna, Italy"},{"name":"Health Sciences and Technologies , Interdepartmental Center for Industrial Research, Alma Mater Studiorum University of Bologna, Bologna, 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