{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:46:27Z","timestamp":1793123187193,"version":"4.5.0"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia national funds","award":["UIDB\/04436\/2020"],"award-info":[{"award-number":["UIDB\/04436\/2020"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia national funds","award":["UIDP\/04436\/2020"],"award-info":[{"award-number":["UIDP\/04436\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Photobiomodulation (PBM) is not implemented in routine clinical management for knee osteoarthritis. This study aims to systematically investigate the effects of PBM in patients with knee osteoarthritis, comparing with placebo to understand its true clinical effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, EMBASE, Web of Science, and Cochrane databases were searched up to October 2023. Randomized placebo-controlled trials applying PBM versus placebo were included. Study characteristics, intervention parameters, and patient-reported and physical examination outcome measures were collected. The risk of bias was judged using the Cochrane risk-of-bias tool for randomized trials (version 2) and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) to interpret the certainty of results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ten studies were included comprising 542 participants. All studies were judged with unclear to a high risk of bias. Meta-analysis for pain at rest (6 studies) showed that PBM significantly reduced pain at rest as compared to placebo (\u22120.7 [95% CI\u2009=\u2009\u22121.1 to \u22120.2]), moderate effect, very low certainty of evidence, whereas for the Timed \u201cUp &amp; Go\u201d Test (three studies), no significant effect was detected. Statistically significantly within-group (PBM) mean improvement was detected for pain, Lequesne Index, and gait performance outcomes, but not always clinically relevant or significant when compared to placebo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PBM reduces pain intensity in patients with knee osteoarthritis and may improve disability. However, the very low certainty of evidence does not allow to recommend its isolated use but may be used to complement other widely recommended therapies. More rigorous clinical trials and the revision of the recommended dosage guidelines are warranted to increase the strength of evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>The findings indicate that photobiomodulation can reduce pain and improve disability in patients with knee osteoarthritis. However, researchers should continue to investigate isolated photobiomodulation intervention versus placebo and extend the dosage guidelines to other types of light emitters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ptj\/pzae073","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T16:40:05Z","timestamp":1716309605000},"source":"Crossref","is-referenced-by-count":19,"title":["Effectiveness of Photobiomodulation in Reducing Pain and Disability in Patients With Knee Osteoarthritis: A Systematic Review With Meta-Analysis"],"prefix":"10.1093","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9617-5910","authenticated-orcid":false,"given":"Sofia","family":"Oliveira","sequence":"first","affiliation":[{"name":"CMEMS \u2013 UMinho, University of Minho , Guimar\u00e3es, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Andrade","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Espregueira\u2013FIFA Medical Centre of Excellence , Porto, Portugal"},{"name":"Dom Henrique Research Centre , Porto, Portugal"},{"name":"Porto Biomechanics Laboratory (LABIOMEP) , Faculty of Sports, , Porto, Portugal"},{"name":"University of Porto , Faculty of Sports, , Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Valente","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Espregueira\u2013FIFA Medical Centre of Excellence , Porto, Portugal"},{"name":"Dom Henrique Research Centre , Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Espregueira-Mendes","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Espregueira\u2013FIFA Medical Centre of Excellence , Porto, Portugal"},{"name":"Dom Henrique Research Centre , Porto, Portugal"},{"name":"ICVS\/3B's-PT Government Associate Laboratory , Braga\/Guimar\u00e3es, Portugal"},{"name":"3B\u2019s Research Group-Biomaterials , Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, , AvePark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, Barco, Guimar\u00e3es, Portugal"},{"name":"University of Minho , Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, , AvePark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, Barco, Guimar\u00e3es, Portugal"},{"name":"School of Medicine, University of Minho , Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe S","family":"Silva","sequence":"additional","affiliation":[{"name":"CMEMS \u2013 UMinho, University of Minho , Guimar\u00e3es, Portugal"},{"name":"LABBELS \u2013 Associate Laboratory , Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betina B","family":"Hinckel","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, William Beaumont Hospital , Royal Oak, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d3scar","family":"Carvalho","sequence":"additional","affiliation":[{"name":"CMEMS \u2013 UMinho, University of Minho , Guimar\u00e3es, Portugal"},{"name":"LABBELS \u2013 Associate Laboratory , Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Leal","sequence":"additional","affiliation":[{"name":"CMEMS \u2013 UMinho, University of Minho , Guimar\u00e3es, Portugal"},{"name":"Dom Henrique Research Centre , Porto, Portugal"},{"name":"LABBELS \u2013 Associate Laboratory , Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"2024090212272087000_ref1","first-page":"274","article-title":"Non-operative treatment options for knee osteoarthritis: current concepts","volume":"3","author":"Parker","year":"2018","journal-title":"J ISAKOS Jt Disord Orthop Sport Med"},{"key":"2024090212272087000_ref2","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.joca.2016.03.012","article-title":"Economic impact of lower-limb osteoarthritis worldwide: a systematic review of cost-of-illness studies","volume":"24","author":"Salmon","year":"2016","journal-title":"Osteoarthr Cartil"},{"key":"2024090212272087000_ref3","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.joca.2019.03.005","article-title":"Health resource use and costs of symptomatic knee and\/or hip osteoarthritis","volume":"27","author":"Salmon","year":"2019","journal-title":"Osteoarthr Cartil"},{"key":"2024090212272087000_ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-022-05306-9","article-title":"The economic burden of knee and hip osteoarthritis: absenteeism and costs in the Dutch workforce","volume":"23","author":"Hardenberg","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"key":"2024090212272087000_ref5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12891-019-2525-0","article-title":"Osteoarthritis\u2014a systematic review of long-term safety implications for osteoarthritis of the knee","volume":"20","author":"Charlesworth","year":"2019","journal-title":"BMC Musculoskelet Disord"},{"key":"2024090212272087000_ref6","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/art.41142","article-title":"2019 American College of Rheumatology\/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee","volume":"72","author":"Kolasinski","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"2024090212272087000_ref7","doi-asserted-by":"crossref","first-page":"1700S","DOI":"10.1177\/19476035211007902","article-title":"In vitro and in vivo effects of light therapy on cartilage regeneration for knee osteoarthritis\u00a0: a systematic review","volume":"13","author":"Oliveira","year":"2021","journal-title":"Cartilage"},{"key":"2024090212272087000_ref8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1109\/JSTQE.2016.2561201","article-title":"Proposed mechanisms of photobiomodulation or low-level light therapy","volume":"22","author":"De Freitas","year":"2016","journal-title":"IEEE J Sel Top Quantum Electron"},{"key":"2024090212272087000_ref9","article-title":"EULAR recommendations for the health professional\u2019s approach to pain management in inflammatory arthritis and osteoarthritis","volume":"77","author":"Geenen","year":"2018","journal-title":"Ann Rheum Dis"},{"key":"2024090212272087000_ref10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.joca.2014.01.003","article-title":"OARSI guidelines for the non-surgical management of knee osteoarthritis","volume":"22","author":"McAlindon","year":"2014","journal-title":"Osteoarthr Cartil"},{"key":"2024090212272087000_ref11","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/j.joca.2015.04.005","article-title":"Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis","volume":"23","author":"Huang","year":"2015","journal-title":"Osteoarthr Cartil"},{"key":"2024090212272087000_ref12","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.15171\/jlms.2017.s3","article-title":"Safety and effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis","volume":"8","author":"Rayegani","year":"2017","journal-title":"J Lasers Med Sci"},{"key":"2024090212272087000_ref13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2019-031142","article-title":"Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials","volume":"9","author":"Stausholm","year":"2019","journal-title":"BMJ Open"},{"key":"2024090212272087000_ref14","first-page":"1","article-title":"Laser acupuncture for patients with knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials","volume":"2019","author":"Chen","year":"2019","journal-title":"Evid-Based Complement Altern Med"},{"key":"2024090212272087000_ref15","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s10103-020-03223-8","article-title":"Association of photobiomodulation therapy (PBMT) and exercises programs in pain and functional capacity of patients with knee osteoarthritis (KOA): a systematic review of randomized trials","volume":"36","author":"Vass\u00e3o","year":"2021","journal-title":"Lasers Med Sci"},{"key":"2024090212272087000_ref16","first-page":"85","article-title":"Effects of low-level and high-intensity laser therapy as adjunctive to rehabilitation exercise on pain, stiffness and function in knee osteoarthritis: a systematic review and meta-analysis","volume":"114","author":"Ahmad","year":"2022","journal-title":"Physiother (United Kingdom)"},{"key":"2024090212272087000_ref17","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3233\/BMR-191738","article-title":"Effectiveness of high-intensity laser therapy in the management of patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials","volume":"33","author":"Song","year":"2020","journal-title":"J Back Musculoskelet Rehabil"},{"key":"2024090212272087000_ref18","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/08990220.2022.2157387","article-title":"Effect of low-level laser therapy plus exercise therapy on pain, range of motion, muscle strength, and function in knee osteoarthritis\u2014a systematic review and meta-analysis","volume":"40","author":"Malik","year":"2022","journal-title":"Somatosens Mot Res"},{"key":"2024090212272087000_ref19","first-page":"372","article-title":"Statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2020","journal-title":"BMJ"},{"key":"2024090212272087000_ref20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1136\/bjsports-2021-103987","article-title":"Implementing the 27 PRISMA 2020 Statement items for systematic reviews in the sport and exercise medicine, musculoskeletal rehabilitation and sports science fields: the PERSiST (implementing Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science) guidance","volume":"56","author":"Ardern","year":"2021","journal-title":"Br J Sports Med"},{"key":"2024090212272087000_ref21","article-title":"Effectiveness of light therapy for knee osteoarthritis treatment: protocol for a systematic review with meta-analysis","author":"Oliveira"},{"key":"2024090212272087000_ref22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1089\/pho.2015.9848","article-title":"Low-level light\/laser therapy versus photobiomodulation therapy","volume":"33","author":"Anders","year":"2015","journal-title":"Photomed Laser Surg"},{"key":"2024090212272087000_ref23","doi-asserted-by":"crossref","DOI":"10.1002\/9781119536604","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins","year":"2019"},{"key":"2024090212272087000_ref24","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"2024090212272087000_ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2288-14-25","article-title":"The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method","volume":"14","author":"Inthout","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"2024090212272087000_ref26","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/sim.650","article-title":"A comparison of statistical methods for meta-analysis","volume":"20","author":"Brockwell","year":"2001","journal-title":"Stat Med"},{"key":"2024090212272087000_ref27","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"1989"},{"key":"2024090212272087000_ref28","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"2024090212272087000_ref29","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/jrsm.11","article-title":"Outlier and influence diagnostics for meta-analysis","volume":"1","author":"Viechtbauer","year":"2010","journal-title":"Res Synth Methods"},{"key":"2024090212272087000_ref30","doi-asserted-by":"crossref","article-title":"The Western Ontario and McMaster Universities Osteoarthritis, Lequesne Algofunctional index, Arthritis Impact Measurement Scale-short form, and Visual Analogue Scale in patients with knee osteoarthritis: responsiveness and minimal clinically important","author":"Salehi","DOI":"10.1080\/09638288.2022.2084776"},{"key":"2024090212272087000_ref31","doi-asserted-by":"crossref","first-page":"e000685","DOI":"10.1136\/rmdopen-2018-000685","article-title":"Multidimensional minimal clinically important differences in knee osteoarthritis after comprehensive rehabilitation: a prospective evaluation from the Bad Zurzach Osteoarthritis Study","volume":"4","author":"Angst","year":"2018","journal-title":"RMD Open"},{"key":"2024090212272087000_ref32","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s12891-022-05262-4","article-title":"Minimal clinically important difference for improvement in Six-minute Walk Test in persons with knee osteoarthritis after total knee arthroplasty","volume":"23","author":"King","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"key":"2024090212272087000_ref33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-015-0637-8","article-title":"The reliability and minimal detectable change of Timed \"Up and Go\" test in individuals with grade 1-3 knee osteoarthritis","volume":"16","author":"Alghadir","year":"2015","journal-title":"BMC Musculoskelet Disord"},{"key":"2024090212272087000_ref34","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000017880","article-title":"Immediate effects of kinesiology tape on the pain and gait function in older adults with knee osteoarthritis","volume":"98","author":"Park","year":"2019","journal-title":"Medicine (Baltimore)"},{"key":"2024090212272087000_ref35","volume-title":"GRADE Handbook for Grading Quality of Evidence and Strength of Recommendations.","author":"Sch\u00fcnemann","year":"2013"},{"key":"2024090212272087000_ref36","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s40279-023-01927-9","article-title":"The perils of misinterpreting and misusing \u201cpublication bias\u201d in meta-analyses: an education review on funnel plot-based methods","volume":"54","author":"Afonso","year":"2023","journal-title":"Sport Med"},{"key":"2024090212272087000_ref37","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1007\/s10103-020-02989-1","article-title":"Level of pain, muscle strength and posture: effects of PBM on an exercise program in women with knee osteoarthritis\u2014a randomized controlled trial","volume":"35","author":"Vass\u00e3o","year":"2020","journal-title":"Lasers Med Sci"},{"key":"2024090212272087000_ref38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/9163618","article-title":"Effectiveness of high intensity laser therapy for reduction of pain in knee osteoarthritis","volume":"2016","author":"Angelova","year":"2016","journal-title":"Pain Res Manag"},{"key":"2024090212272087000_ref39","doi-asserted-by":"crossref","first-page":"269","DOI":"10.5604\/15093492.1002257","article-title":"Influence of various laser therapy methods on knee joint pain and function in patients with knee osteoarthritis","volume":"14","author":"Gworys","year":"2012","journal-title":"Ortop Traumatol Rehabil"},{"key":"2024090212272087000_ref40","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.apmr.2012.01.003","article-title":"Short-term effects of 890-nanometer radiation on pain, physical activity, and postural stability in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study","volume":"93","author":"Hsieh","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"key":"2024090212272087000_ref41","first-page":"71","article-title":"Therapeutic effects of low level laser therapy (LLLT) in knee osteoarthritis, compared to therapeutic ultrasound","volume":"3","author":"Rayegani","year":"2012","journal-title":"J LASERS Med Sci"},{"key":"2024090212272087000_ref42","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1590\/S0102-36162011000500008","article-title":"Short-term efficacy of low-level laser therapy in patients with knee osteoarthritis: a randomized placebo-controlled, double-blind clinical trial","volume":"46","author":"Fukuda","year":"2011","journal-title":"Rev Bras Ortop (English Ed)"},{"key":"2024090212272087000_ref43","first-page":"254","article-title":"Low power laser treatment in patients with knee osteoarthritis","volume":"134","author":"Tascioglu","year":"2004","journal-title":"Swiss Med Wkly"},{"key":"2024090212272087000_ref44","first-page":"155","article-title":"Low power Ga-Al-As laser treatment of painful osteoarthritis of the knee. A double-blind placebo-controlled study","volume":"26","author":"B\u00fclow","year":"1994","journal-title":"Scand J Rehabil Med"},{"key":"2024090212272087000_ref45","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1532-5415.1992.tb01824.x","article-title":"Improvement of pain and disability in elderly patients with degenerative osteoarthritis of the knee treated with narrow-band light therapy","volume":"40","author":"Stelian","year":"1992","journal-title":"J Am Geriatr Soc"},{"key":"2024090212272087000_ref46","first-page":"698","article-title":"Customized photobiomodulation modulates pain and alters thermography pattern in patients with knee osteoarthritis: a randomized double-blind pilot study","volume":"40","author":"Pinto","year":"2022","journal-title":"Photobiomodul Photomed Laser Surg"},{"key":"2024090212272087000_ref47","article-title":"Recommended treatment doses for low level laser therapy 904 nm wavelength","author":"WALT: World Association for Photobiomodulation"},{"key":"2024090212272087000_ref48","article-title":"Recommended treatment doses for low level laser therapy 780\u2013860 nm wavelength","author":"WALT: World Association for Photobiomodulation"},{"key":"2024090212272087000_ref49","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2203\/dose-response.09-027.Hamblin","article-title":"Biphasic dose response in low level light therapy","volume":"7","author":"Huang","year":"2009","journal-title":"Dose-Response"},{"key":"2024090212272087000_ref50","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/s41584-020-00523-9","article-title":"Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines","volume":"17","author":"Arden","year":"2021","journal-title":"Nat Rev Rheumatol"},{"key":"2024090212272087000_ref51","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1136\/bjsports-2015-095424","article-title":"Exercise for osteoarthritis of the knee: a Cochrane systematic review","volume":"49","author":"Fransen","year":"2015","journal-title":"Br J Sports Med"}],"container-title":["Physical Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ptj\/advance-article-pdf\/doi\/10.1093\/ptj\/pzae073\/57824068\/pzae073.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ptj\/article-pdf\/104\/8\/pzae073\/58993910\/pzae073.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ptj\/article-pdf\/104\/8\/pzae073\/58993910\/pzae073.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T08:52:34Z","timestamp":1725267154000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ptj\/article\/doi\/10.1093\/ptj\/pzae073\/7679396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":51,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ptj\/pzae073","relation":{},"ISSN":["0031-9023","1538-6724"],"issn-type":[{"value":"0031-9023","type":"print"},{"value":"1538-6724","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,8]]},"published":{"date-parts":[[2024,5,22]]},"article-number":"pzae073"}}