{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:46:13Z","timestamp":1790815573116,"version":"4.1.0"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Physical therapy is moving toward digitally supported, independent, home-based care to improve therapy accessibility and adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This trial evaluated the clinical feasibility and potential effectiveness of Strolll, an augmented reality (AR) neurorehabilitation platform offering gamified gait-and-balance exercises with optional assistive AR cueing for individuals with Parkinson disease, implemented in real-world clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and setting<\/jats:title>\n                    <jats:p>In this pragmatic clinical trial, 15 Dutch health care practices were onboarded, 28 therapists trained, and 100 individuals with Parkinson disease (Hoehn and Yahr stages 1-3) included. All participants followed the T0-usual-care-control-T1-Strolll-intervention-T2 procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>The Strolll intervention consisted of 2-week supervised in-clinic training followed by 6\u00a0weeks, 5 sessions per week of 30 active minutes each, independent home-based training.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No serious adverse events occurred; only 2 non-injurious falls were reported in &amp;gt;60.000 exercise minutes. Adherence was high (96% session adherence, 91% active minutes\/session adherence). Therapists prescribed the program progressively, with significantly higher game-play levels over time. Participants\u2019 exercise performance increased over time. Participants and therapists rated user experience and technology acceptance positively. Timed \u201cUp &amp; Go\u201d test and 10-meter walk test (10MWT) (fast speed) scores improved significantly after the intervention period only. Five times sit-to-stand test, 10MWT (comfortable speed), and Mini Balance Evaluation Systems Test scores improved after both usual-care and intervention periods. Falls Efficacy Scale-International scores showed no significant improvements. AR cueing was deemed beneficial for a subset of participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Strolll is a safe, adherable, progressive, usable, and well-accepted therapist-managed, home-based intervention for people with Parkinson disease, with the potential to improve gait, balance, and fall-risk indicators. Findings on the integration of AR cueing highlight the importance of an individualized approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance<\/jats:title>\n                    <jats:p>Implementing AR rehabilitation technologies like Strolll in the clinical pathway is feasible, offering a safe and scalable way for individuals to train independently, potentially improving accessibility of care and broadening its use to physical activity promotion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>This study was registered at ClinicalTrials.gov (NCT06590987).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ptj\/pzag012","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T12:41:24Z","timestamp":1770381684000},"source":"Crossref","is-referenced-by-count":4,"title":["Cueing-assisted gamified augmented-reality home rehabilitation for gait and balance in people with Parkinson disease: feasibility and effectiveness in the clinical pathway"],"prefix":"10.1093","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4554-3628","authenticated-orcid":false,"given":"Eva M","family":"Hoogendoorn","sequence":"first","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism and MHeNs Institute of Mental Health and Neurosciences, Faculty of Health, Medicine and Life Sciences, Maastricht University , Maastricht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne J","family":"Geerse","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annejet T","family":"van Dam","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybren J","family":"van Hall","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter F","family":"van Doorn","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism and MHeNs Institute of Mental Health and Neurosciences, Faculty of Health, Medicine and Life Sciences, Maastricht University , Maastricht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9963-8087","authenticated-orcid":false,"given":"Lotte E S","family":"Hardeman","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco J M","family":"Hoozemans","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F","family":"Stins","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melvyn","family":"Roerdink","sequence":"additional","affiliation":[{"name":"Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Nutrition and Movement Sciences, NUTRIM Institute of Nutrition and Translational Research in Metabolism and MHeNs Institute of Mental Health and Neurosciences, Faculty of Health, Medicine and Life Sciences, Maastricht University , Maastricht ,","place":["The Netherlands"]},{"name":"Department of Science, Strolll Ltd. , Stafford ST16 2LP ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"issue":"s1","key":"2026032711154030600_ref1","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.3233\/jpd-181474","article-title":"The emerging evidence of the Parkinson pandemic","volume":"8","author":"Dorsey","year":"2018","journal-title":"J Parkinsons Dis"},{"issue":"3","key":"2026032711154030600_ref2","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000098468","article-title":"Influence of motor symptoms upon the quality of life of patients with Parkinson\u2019s disease","volume":"57","author":"G\u00f3mez-Esteban","year":"2007","journal-title":"Eur Neurol"},{"key":"2026032711154030600_ref3","volume-title":"European Physiotherapy Guideline for Parkinson\u2019s Disease","author":"Keus","year":"2014"},{"issue":"4","key":"2026032711154030600_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzab302","article-title":"Physical therapist Management of Parkinson Disease: a clinical practice guideline from the American Physical Therapy Association","volume":"102","author":"Osborne","year":"2022","journal-title":"Phys Ther"},{"issue":"6","key":"2026032711154030600_ref5","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1111\/jep.13999","article-title":"Assessing the factors that influence the utilization and delivery of rehabilitation services among persons with Parkinson's disease: a scoping review","volume":"30","author":"Agoriwo","year":"2024","journal-title":"J Eval Clin Pract"},{"issue":"1","key":"2026032711154030600_ref6","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.parkreldis.2012.07.006","article-title":"Self reported adherence to a home-based exercise programme among people with Parkinson's disease","volume":"19","author":"Pickering","year":"2013","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"2026032711154030600_ref7","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1186\/s12877-023-04595-6","article-title":"The effect of home-based exercise on motor symptoms, quality of life and functional performance in Parkinson's disease: a systematic review and meta-analysis","volume":"23","author":"Yang","year":"2023","journal-title":"BMC Geriatr"},{"issue":"11","key":"2026032711154030600_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzaf121","article-title":"Effect of telerehabilitation in Parkinson disease: a systematic review and meta-analysis","volume":"105","author":"Darbandsari","year":"2025","journal-title":"Phys Ther"},{"issue":"5","key":"2026032711154030600_ref9","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1177\/0269215520976265","article-title":"Home-based exercise monitored with telehealth is feasible and acceptable compared to Centre-based exercise in Parkinson\u2019s disease: a randomised pilot study","volume":"35","author":"Flynn","year":"2021","journal-title":"Clin Rehabil"},{"key":"2026032711154030600_ref10","doi-asserted-by":"publisher","first-page":"110192","DOI":"10.1016\/j.chaos.2020.110192","article-title":"Effectiveness of gamification for the rehabilitation of neurodegenerative disorders","volume":"140","author":"Adlakha","year":"2020","journal-title":"Chaos, Solitons Fractals"},{"issue":"1","key":"2026032711154030600_ref11","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s11556-022-00296-y","article-title":"Going digital \u2013 a commentary on the terminology used at the intersection of physical activity and digital health","volume":"19","author":"Herold","year":"2022","journal-title":"Eur Rev Aging Phys Act"},{"key":"2026032711154030600_ref12","doi-asserted-by":"publisher","first-page":"1373740","DOI":"10.3389\/fneur.2024.1373740","article-title":"Remotely prescribed, monitored, and tailored home-based gait-and-balance exergaming using augmented reality glasses: a clinical feasibility study in people with Parkinson's disease","volume":"15","author":"Hardeman","year":"2024","journal-title":"Front Neurol"},{"issue":"Suppl 2","key":"2026032711154030600_ref13","doi-asserted-by":"publisher","first-page":"S475","DOI":"10.1002\/mds.21978","article-title":"Cueing for freezing of gait in patients with Parkinson's disease: a rehabilitation perspective","volume":"23","author":"Nieuwboer","year":"2008","journal-title":"Mov Disord"},{"key":"2026032711154030600_ref14","doi-asserted-by":"publisher","first-page":"100332","DOI":"10.1016\/j.prdoa.2025.100332","article-title":"Effects of augmented reality cueing strategies on freezing of gait: the ELIMINATE FoG trial","volume":"12","author":"Baugher","year":"2025","journal-title":"Clin Park Relat Disord"},{"key":"2026032711154030600_ref15","doi-asserted-by":"publisher","first-page":"105189","DOI":"10.1016\/j.neubiorev.2023.105189","article-title":"One cue does not fit all: a systematic review with meta-analysis of the effectiveness of cueing on freezing of gait in Parkinson's disease","volume":"150","author":"Cosentino","year":"2023","journal-title":"Neurosci Biobehav Rev"},{"issue":"20","key":"2026032711154030600_ref16","doi-asserted-by":"publisher","first-page":"e2253","DOI":"10.1212\/WNL.0000000000201159","article-title":"Evaluation of compensation strategies for gait impairment in patients with Parkinson disease","volume":"99","author":"Tosserams","year":"2022","journal-title":"Neurology"},{"key":"2026032711154030600_ref17","doi-asserted-by":"publisher","first-page":"1512409","DOI":"10.3389\/fneur.2025.1512409","article-title":"Cueing-assisted gamified augmented-reality gait-and-balance rehabilitation at home for people with Parkinson\u2019s disease: protocol of a pragmatic randomized controlled trial implemented in the clinical pathway","volume":"16","author":"Geerse","year":"2025","journal-title":"Front Neurol"},{"issue":"1","key":"2026032711154030600_ref18","doi-asserted-by":"publisher","DOI":"10.1525\/collabra.117094","article-title":"When and how to deviate from a preregistration","volume":"10","author":"Lakens","year":"2024","journal-title":"Collabra: Psychology"},{"issue":"11","key":"2026032711154030600_ref19","doi-asserted-by":"publisher","first-page":"1987","DOI":"10.1377\/hlthaff.2017.0832","article-title":"ParkinsonNet: a low-cost health care innovation with a systems approach from the Netherlands","volume":"36","author":"Bloem","year":"2017","journal-title":"Health Aff"},{"issue":"24","key":"2026032711154030600_ref20","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","article-title":"World Health Organization 2020 guidelines on physical activity and sedentary behaviour","volume":"54","author":"Bull","year":"2020","journal-title":"Br J Sports Med"},{"key":"2026032711154030600_ref21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/978-3-540-89350-9_6","volume-title":"HCI and Usability for Education and Work","author":"Laugwitz","year":"2008"},{"issue":"4","key":"2026032711154030600_ref22","doi-asserted-by":"publisher","first-page":"40","DOI":"10.9781\/ijimai.2017.445","article-title":"Construction of a benchmark for the User Experience Questionnaire (UEQ)","volume":"4","author":"Schrepp","year":"2017","journal-title":"Int J Interact Multimed Artif Intell"},{"issue":"3","key":"2026032711154030600_ref23","doi-asserted-by":"publisher","first-page":"425","DOI":"10.2307\/30036540","article-title":"User acceptance of information technology: toward a unified view","volume":"27","author":"Venkatesh","year":"2003","journal-title":"MIS Q"},{"issue":"8","key":"2026032711154030600_ref24","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1007\/s00415-018-8921-9","article-title":"The clinical significance of 10-m walk test standardizations in Parkinson\u2019s disease","volume":"265","author":"Lindholm","year":"2018","journal-title":"J Neurol"},{"issue":"9","key":"2026032711154030600_ref25","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1016\/j.apmr.2011.04.008","article-title":"Five times sit-to-stand test performance in Parkinson's disease","volume":"92","author":"Duncan","year":"2011","journal-title":"Arch Phys Med Rehabil"},{"issue":"7","key":"2026032711154030600_ref26","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1016\/j.apmr.2013.02.020","article-title":"Using the timed up & go test in a clinical setting to predict falling in Parkinson's disease","volume":"94","author":"Nocera","year":"2013","journal-title":"Arch Phys Med Rehabil"},{"issue":"5","key":"2026032711154030600_ref27","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.bjpt.2019.07.006","article-title":"The mini-BESTest is an independent predictor of falls in Parkinson disease","volume":"24","author":"Lopes","year":"2020","journal-title":"Braz J Phys Ther"},{"key":"2026032711154030600_ref28","author":"JASP Team","year":"2024"},{"issue":"4","key":"2026032711154030600_ref29","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.gaitpost.2009.07.108","article-title":"Reliability of the new freezing of gait questionnaire: agreement between patients with Parkinson's disease and their carers","volume":"30","author":"Nieuwboer","year":"2009","journal-title":"Gait Posture"},{"key":"2026032711154030600_ref30","doi-asserted-by":"publisher","first-page":"102283","DOI":"10.1016\/j.displa.2022.102283","article-title":"Optical see-through augmented reality can induce severe motion sickness","volume":"74","author":"Kaufeld","year":"2022","journal-title":"Displays"},{"issue":"1","key":"2026032711154030600_ref31","doi-asserted-by":"publisher","first-page":"11693","DOI":"10.1038\/s41598-024-62338-y","article-title":"How different text display patterns affect cybersickness in augmented reality","volume":"14","author":"Zhang","year":"2024","journal-title":"Sci Rep"},{"issue":"2","key":"2026032711154030600_ref32","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1007\/s00415-016-8365-z","article-title":"Long-term risk of falls in an incident Parkinson\u2019s disease cohort: the Norwegian ParkWest study","volume":"264","author":"Hiorth","year":"2017","journal-title":"J Neurol"},{"issue":"4","key":"2026032711154030600_ref33","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.jphys.2019.08.003","article-title":"Home-based prescribed exercise improves balance-related activities in people with Parkinson's disease and has benefits similar to Centre-based exercise: a systematic review","volume":"65","author":"Flynn","year":"2019","journal-title":"J Phys"},{"key":"2026032711154030600_ref34","doi-asserted-by":"publisher","first-page":"e70802","DOI":"10.2196\/70802","article-title":"Home-based augmented reality exercise for people with Parkinson disease: qualitative acceptability study","volume":"12","author":"Hardeman","year":"2025","journal-title":"JMIR Rehabil Assist Technol"},{"issue":"3","key":"2026032711154030600_ref35","doi-asserted-by":"publisher","first-page":"217","DOI":"10.3109\/17483107.2015.1111944","article-title":"Evaluating change in virtual reality adoption for brain injury rehabilitation following knowledge translation","volume":"12","author":"Glegg","year":"2017","journal-title":"Disabil Rehabil Assist Technol"},{"issue":"1","key":"2026032711154030600_ref36","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1186\/s12913-016-1807-6","article-title":"A knowledge translation intervention to enhance clinical application of a virtual reality system in stroke rehabilitation","volume":"16","author":"Levac","year":"2016","journal-title":"BMC Health Serv Res"},{"key":"2026032711154030600_ref37","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.gaitpost.2020.05.004","article-title":"Responsiveness and minimal clinically important difference of the mini-BESTest in patients with Parkinson\u2019s disease","volume":"80","author":"Godi","year":"2020","journal-title":"Gait Posture"},{"issue":"4","key":"2026032711154030600_ref38","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3233\/nre-172379","article-title":"Are functional mobility tests responsive to group physical therapy intervention in individuals with Parkinson\u2019s disease?","volume":"42","author":"Spagnuolo","year":"2018","journal-title":"NeuroRehabilitation"},{"issue":"4","key":"2026032711154030600_ref39","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1097\/npt.0000000000000055","article-title":"Defining the clinically meaningful difference in gait speed in persons with Parkinson disease","volume":"38","author":"Hass","year":"2014","journal-title":"J Neurol Phys Ther"},{"issue":"9","key":"2026032711154030600_ref40","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afaf241","article-title":"Minimal clinically important difference and substantial clinical benefits for single- and dual-task timed up and go test following motor-cognitive training in Parkinson\u2019s disease","volume":"54","author":"Taghizadeh","year":"2025","journal-title":"Age Ageing"},{"key":"2026032711154030600_ref41","doi-asserted-by":"publisher","first-page":"n2061","DOI":"10.1136\/bmj.n2061","article-title":"A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance","volume":"374","author":"Skivington","year":"2021","journal-title":"BMJ"},{"key":"2026032711154030600_ref42","doi-asserted-by":"publisher","DOI":"10.1186\/ISRCTN41469859","article-title":"Augmented reality (reality DTx\u00ae) compared to routine physiotherapy for patients with Parkinson's","author":"Arundel","year":"2025","journal-title":"ISRCTN"},{"issue":"9","key":"2026032711154030600_ref43","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.3390\/s19092183","article-title":"The validity of a mixed reality-based automated functional mobility assessment","volume":"19","author":"Sun","year":"2019","journal-title":"Sensors"},{"issue":"17","key":"2026032711154030600_ref44","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.3390\/s24175485","article-title":"Gait and balance assessments with augmented reality glasses in people with Parkinson\u2019s disease: concurrent validity and test\u2013retest reliability","volume":"24","author":"Bergem","year":"2024","journal-title":"Sensors"},{"issue":"4","key":"2026032711154030600_ref45","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.3390\/s25041230","article-title":"Gait parameters can Be derived reliably and validly from augmented reality glasses in people with Parkinson\u2019s disease performing 10-m walk tests at comfortable and fast speeds","volume":"25","author":"Doorn","year":"2025","journal-title":"Sensors"},{"issue":"5","key":"2026032711154030600_ref46","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.3390\/s22052009","article-title":"The Microsoft HoloLens 2 provides accurate measures of gait, turning, and functional mobility in healthy adults","volume":"22","author":"Miller Koop","year":"2022","journal-title":"Sensors"},{"key":"2026032711154030600_ref47","volume-title":"Capaciteitsraming Fysiotherapie","author":"Batenburg","year":"2018"},{"key":"2026032711154030600_ref48","volume-title":"Missies Gezondheid & Zorg 2024\u20132027","author":"Ministerie van Volksgezondheid Welzijn en Sport","year":"2023"},{"issue":"12","key":"2026032711154030600_ref49","doi-asserted-by":"publisher","first-page":"2214","DOI":"10.1007\/s00415-011-6097-7","article-title":"Physical inactivity in Parkinson's disease","volume":"258","author":"Nimwegen","year":"2011","journal-title":"J Neurol"},{"issue":"12","key":"2026032711154030600_ref50","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1001\/jamaneurol.2021.3926","article-title":"Association of Physical Activity, including amount and maintenance, with all-cause mortality in Parkinson disease","volume":"78","author":"Yoon","year":"2021","journal-title":"JAMA Neurol"},{"issue":"8","key":"2026032711154030600_ref51","doi-asserted-by":"publisher","first-page":"e859","DOI":"10.1212\/WNL.0000000000013218","article-title":"Long-term effect of regular physical activity and exercise habits in patients with early Parkinson disease","volume":"98","author":"Tsukita","year":"2022","journal-title":"Neurology"},{"issue":"2","key":"2026032711154030600_ref52","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1002\/ana.26291","article-title":"Aerobic exercise alters brain function and structure in Parkinson's disease: a randomized controlled trial","volume":"91","author":"Johansson","year":"2022","journal-title":"Ann Neurol"},{"issue":"11","key":"2026032711154030600_ref53","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/S1474-4422(19)30285-6","article-title":"Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson's disease: a double-blind, randomised controlled trial","volume":"18","author":"Kolk","year":"2019","journal-title":"Lancet Neurol"}],"container-title":["Physical Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ptj\/advance-article-pdf\/doi\/10.1093\/ptj\/pzag012\/66840421\/pzag012.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ptj\/article-pdf\/106\/3\/pzag012\/66840421\/pzag012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ptj\/article-pdf\/106\/3\/pzag012\/66840421\/pzag012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T15:15:50Z","timestamp":1774624550000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ptj\/article\/doi\/10.1093\/ptj\/pzag012\/8471200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,3]]}},"URL":"https:\/\/doi.org\/10.1093\/ptj\/pzag012","relation":{},"ISSN":["0031-9023","1538-6724"],"issn-type":[{"value":"0031-9023","type":"print"},{"value":"1538-6724","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2026,2,10]]},"article-number":"pzag012"}}