{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T15:21:36Z","timestamp":1776784896828,"version":"3.51.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA016672"],"award-info":[{"award-number":["P30CA016672"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background and Purpose<\/jats:title>\n                  <jats:p>Lower extremity edema, which can be caused by several factors, is often poorly managed with commonly prescribed compression stockings and diuretics. Diuretics are often erroneously given in all forms of edema and may cause problems because their long-term application may induce chronicity of the edema due to disturbance of the renin-angiotensin relationship. Compression therapy, although effective against venous edema, is widely underused.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case Description<\/jats:title>\n                  <jats:p>A 64-year-old man with a history of hypertension, coronary artery disease, psoriasis, and multiple myeloma was admitted to the hospital for neutropenic fever, right lower extremity (RLE) cellulitis, bilateral lower extremity (BLE) weakness, RLE pain, and significant BLE edema. The patient was referred to a lymphedema-certified therapist to apply lower extremity multilayered compression bandaging and document serial limb circumference measurements.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcomes<\/jats:title>\n                  <jats:p>The patient's weight decreased from 94.5 kg on day 1 of compression bandaging to 86.3 kg on day 7. The circumferences of the affected limbs also decreased.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This case demonstrates the utility of multilayered compression bandaging, typically used in the management of lymphedema, in the control of peripheral edema that is refractory to diuretic therapy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzy072","type":"journal-article","created":{"date-parts":[[2018,6,17]],"date-time":"2018-06-17T19:06:19Z","timestamp":1529262379000},"page":"763-766","source":"Crossref","is-referenced-by-count":5,"title":["Improvement of Refractory Peripheral Edema With Multilayered Compression Bandaging: A Case Report"],"prefix":"10.1093","volume":"98","author":[{"given":"Jegy M","family":"Tennison","sequence":"first","affiliation":[{"name":"Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1414, Houston, TX 77030 (USA)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack B","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Bruera","sequence":"additional","affiliation":[{"name":"Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,8,2]]},"reference":[{"key":"2023011807195615100_bib1","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/iwj.12694","article-title":"Chronic oedema: a prevalent health care problem for UK health services","volume":"14","author":"Moffatt","year":"2017","journal-title":"Int Wound J"},{"key":"2023011807195615100_bib2","first-page":"44","article-title":"Leg edema assessment and management","volume":"23","author":"Simon","year":"2014","journal-title":"Medsurg Nurs"},{"key":"2023011807195615100_bib3","article-title":"Compression therapy for the treatment of chronic venous insufficiency","volume-title":"UpToDate","author":"Armstrong"},{"key":"2023011807195615100_bib4","first-page":"CD000265","article-title":"Compression for venous leg ulcers","volume":"11","author":"O\u2019Meara S","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"2023011807195615100_bib5","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s11936-011-0114-0","article-title":"Compression therapy for treatment of venous disease and limb swelling","volume":"13","author":"Kolluri","year":"2011","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"2023011807195615100_bib6","article-title":"Clinical staging and conservative management of peripheral lymphedema","volume-title":"UpToDate","author":"Mehrara"},{"key":"2023011807195615100_bib7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.jpainsymman.2008.03.019","article-title":"High-dose furosemide and small-volume hypertonic saline solution infusion for the treatment of leg edema in advanced cancer patients","volume":"37","author":"Mercadante","year":"2009","journal-title":"J Pain Symptom Manage"},{"key":"2023011807195615100_bib8","article-title":"Treatment of refractory edema in adults","volume-title":"UpToDate","author":"Brater"},{"key":"2023011807195615100_bib9","article-title":"Principles of compression in venous disease. 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