{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:30:57Z","timestamp":1790767857919,"version":"4.1.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Central Nervous System Recovery Restoration Grant\u2013Washington University Department of Neurology and HealthSouth"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NICHD K12 HD055931"],"award-info":[{"award-number":["NICHD K12 HD055931"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Washington University Institute of Clinical and Translational Sciences","award":["NIH UL1 TR002345"],"award-info":[{"award-number":["NIH UL1 TR002345"]}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006309","name":"American Parkinson Disease Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006309","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Advanced Research Center for Parkinson Disease at Washington University"},{"name":"Greater St Louis Chapter of the APDA"},{"DOI":"10.13039\/100007338","name":"Barnes-Jewish Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>People with Parkinson disease (PD) frequently experience low back pain (LBP), yet the impact of LBP on functional mobility, physical activity, and quality of life (QOL) has not been described in PD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The objectives of this study were to describe body positions and functional activities associated with LBP and to determine the relationships between LBP-related disability and PD motor sign severity, physical activity level, and QOL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>The study was a cross-sectional study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Thirty participants with idiopathic PD (mean age\u00a0=\u00a064.6 years [SD\u00a0=\u00a010.3]; 15 women) completed the Revised Oswestry Disability Questionnaire (RODQ), a measure of LBP-related disability. PD motor symptom severity was measured using the Movement Disorder Society-Unified Parkinson Disease Rating Scale Part III (MDS-UPRDS III). The Physical Activity Scale for the Elderly (PASE) was used to measure self-reported physical activity. The Parkinson Disease Questionnaire-39 (PDQ-39) was used to measure QOL. Descriptive statistics were used to characterize LBP intensity and LBP-related disability. Spearman correlations were used to determine relationships between the RODQ and the MDS-UPDRS III, PASE, and PDQ-39.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>LBP was reported to be of at least moderate intensity by 63.3% of participants. LBP most frequently impaired standing, sleeping, lifting, and walking. The RODQ was significantly related to the MDS-UPDRS III (r\u00a0=\u00a00.38), PASE (r\u00a0=\u00a0\u22120.37), PDQ-39 summary index (r\u00a0=\u00a00.55), PDQ-39 mobility subdomain (r\u00a0=\u00a00.54), and PDQ-39 bodily pain subdomain (r\u00a0=\u00a00.44).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Limitations<\/jats:title>\n                  <jats:p>Limitations included a small sample of people with mild to moderate PD severity, the fact that RODQ is a less frequently used measure of LBP-related disability, and the lack of a non-PD control group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>LBP affected walking, sleeping, standing, and lifting in this small sample of people with mild to moderate PD. Greater LBP-related disability was associated with greater motor sign severity, lower physical activity level, and lower QOL in people with PD.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ptj\/pzz094","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T03:10:06Z","timestamp":1562814606000},"page":"1346-1353","source":"Crossref","is-referenced-by-count":13,"title":["Low Back Pain--Related Disability in Parkinson Disease: Impact on Functional Mobility, Physical Activity, and Quality of Life"],"prefix":"10.1093","volume":"99","author":[{"given":"Ryan P","family":"Duncan","sequence":"first","affiliation":[{"name":"Program in Physical Therapy, Washington University School of Medicine in Saint Louis , 4444 Forest Park Blvd, Campus Box 8502, St Louis, MO 63108 (USA)"},{"name":"Department of Neurology, Washington University School of Medicine in Saint Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda R","family":"Van Dillen","sequence":"additional","affiliation":[{"name":"Program in Physical Therapy, and Department of Orthopaedic Surgery, Washington University School of Medicine in Saint Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M","family":"Garbutt","sequence":"additional","affiliation":[{"name":"Department of Medicine, and Department of Pediatrics, Washington University School of Medicine in Saint Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gammon M","family":"Earhart","sequence":"additional","affiliation":[{"name":"Program in Physical Therapy, Department of Neurology, and Department of Neuroscience, Washington University School of Medicine in Saint Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel S","family":"Perlmutter","sequence":"additional","affiliation":[{"name":"Department of Neurology, Program in Physical Therapy, Department of Neuroscience, Department of Radiology, and Program in Occupational Therapy, Washington University School of Medicine in Saint Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,7,25]]},"reference":[{"key":"2023011903533373300_ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.2003.tb07458.x","article-title":"Description of Parkinson's disease as a clinical syndrome","volume":"991","author":"Fahn","year":"2003","journal-title":"Ann N Y Acad Sci."},{"key":"2023011903533373300_ref2","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s00702-012-0960-2","article-title":"Musculoskeletal problems in Parkinson's disease","volume":"120","author":"Kim","year":"2013","journal-title":"J Neural Transm (Vienna)."},{"key":"2023011903533373300_ref3","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1007\/s00264-015-3011-4","article-title":"Characteristics and exacerbating factors of chronic low back pain in Parkinson's 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