{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:39:53Z","timestamp":1792600793676,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Among working-age populations globally, occupational injuries and workplace cardiovascular emergencies remain major contributors to morbidity and mortality. This study examined the associations between workplace settings, age groups, and the severity of occupational injuries and cardiovascular events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a nationwide retrospective registry-based observational study using emergency medical services data from Japan, including 454\u2009043 working-age individuals recorded in 2021\u20132023. Workplace settings (office, indoor worksite, factory, outdoor worksite, construction, agriculture, and others) and age groups were analysed in relation to event severity, categorized as non-life-threatening or life-threatening. Multivariable regression models estimated the associations, and workplace\u2013age interactions were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with office settings, all other workplaces were associated with higher odds of life-threatening injuries, particularly agriculture and construction. Increasing age groups were progressively associated with greater injury severity. The workplace setting was associated with the severity of stroke and ischaemic heart disease, particularly in uncontrolled outdoor environments. Stroke severity was elevated in those aged 45\u201359 and 60\u201369\u00a0years, while all older age groups were associated with severe ischaemic heart disease. Workplace\u2013age interactions were significant only for occupational injuries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Workplace and age were interactively and independently associated with the severity of occupational injuries and cardiovascular emergencies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/pubmed\/fdag073","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:50:21Z","timestamp":1792597821000},"source":"Crossref","is-referenced-by-count":0,"title":["Workplace and age associated with severity of occupational injuries and cardiovascular emergencies: a nationwide study in Japan"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1738-2917","authenticated-orcid":false,"given":"Jate","family":"Ratanachina","sequence":"first","affiliation":[{"name":"Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University , 1872 Rama IV Road, Pathumwan, Bangkok 10330 ,","place":["Thailand"]},{"name":"Division of Public Health, Department of Social Medicine, Graduate School of Medicine, The University of Osaka , 2-2 Yamadaoka, Suita, Osaka 565-0871 ,","place":["Japan"]},{"name":"National Heart and Lung Institute, Imperial College London , Emmanuel Kaye Building, 1B Manresa Road, London SW3 6LR ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6712-6930","authenticated-orcid":false,"given":"Atsushi","family":"Hirayama","sequence":"additional","affiliation":[{"name":"Division of Public Health, Department of Social Medicine, Graduate School of Medicine, The University of Osaka , 2-2 Yamadaoka, Suita, Osaka 565-0871 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-0580","authenticated-orcid":false,"given":"Tetsuhisa","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Division of Environmental Medicine and Population Sciences, Department of Social Medicine, Graduate School of Medicine, The University of Osaka , 2-2 Yamadaoka, Suita, Osaka 565-0871 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0644-6129","authenticated-orcid":false,"given":"Kosuke","family":"Kiyohara","sequence":"additional","affiliation":[{"name":"Department of Food Science, Faculty of Home Economics, Otsuma Women\u2019s University , 12 Sanbancho, Chiyoda-ku, Tokyo 102-8357 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