{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:01:35Z","timestamp":1792101695896,"version":"4.4.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,10]]},"DOI":"10.1093\/qjmed\/93.10.685","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T18:37:51Z","timestamp":1027708671000},"page":"685-688","source":"Crossref","is-referenced-by-count":44,"title":["The patient with a systolic murmur: severe aortic stenosis may be missed during cardiovascular examination"],"prefix":"10.1093","volume":"93","author":[{"given":"P.","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pocock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Chambers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,10]]},"reference":[{"key":"key\n\t\t\t\t20170413030547_R1","doi-asserted-by":"crossref","unstructured":"Lindroos M, Kupari M, Heikkila J, Tilvi R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic sample of a random population. J Am Coll Cardiol1993; 21:1220\u20135.","DOI":"10.1016\/0735-1097(93)90249-Z"},{"key":"key\n\t\t\t\t20170413030547_R2","doi-asserted-by":"crossref","unstructured":"Pellika PA, Nishimura RA, Bailey KR, Tajik AJ. The natural history of adults with asymptomatic, haemodynamically significant aortic stenosis. J Am Coll Cardiol1990; 15:1012\u201317.","DOI":"10.1016\/0735-1097(90)90234-G"},{"key":"key\n\t\t\t\t20170413030547_R3","doi-asserted-by":"crossref","unstructured":"Horstkotte D, Loogen F. The natural history of aortic valve stenosis. Eur Heart J1988; 9(Suppl E):57\u201364.","DOI":"10.1093\/eurheartj\/9.suppl_E.57"},{"key":"key\n\t\t\t\t20170413030547_R4","doi-asserted-by":"crossref","unstructured":"Lund O, Nielsen TT, Emmertsen K, Flo C, Rasmussen B, Jensen FT, Pilegaard HK, Kristensen LH, Hansen OK. Mortality and worsening prognostic profile during waiting time for valve replacement in aortic stenosis. Thoracic Cardiovasc Surg1996; 44:289\u201395.","DOI":"10.1055\/s-2007-1012039"},{"key":"key\n\t\t\t\t20170413030547_R5","doi-asserted-by":"crossref","unstructured":"Andersen JA, Hansen BF, Lyngborg K. Isolated valvular aortic stenosis. Clinico\u2010pathological findings in an autopsy material of elderly patients. Acta Med Scand1975; 197:61\u20134.","DOI":"10.1111\/j.0954-6820.1975.tb04878.x"},{"key":"key\n\t\t\t\t20170413030547_R6","doi-asserted-by":"crossref","unstructured":"Roldan CA, Shively BK, Crawford MH. Value of cardiovascular physical examination for detecting valvular heart disease in asymptomatic subjects. Am J Cardiol1996; 77:1327\u201331.","DOI":"10.1016\/S0002-9149(96)00200-7"},{"key":"key\n\t\t\t\t20170413030547_R7","doi-asserted-by":"crossref","unstructured":"Etchells E, Glenns V, Shadowitz S, Bell C, Siu S. A bedside clinical prediction rule for detecting moderate or severe aortic stenosis. J Gen Int Med1998; 13:699\u2013704.","DOI":"10.1046\/j.1525-1497.1998.00207.x"},{"key":"key\n\t\t\t\t20170413030547_R8","doi-asserted-by":"crossref","unstructured":"Munt BI, Legget ME, Kraft CD, Miyake\u2010Hull CY, Fujioka M, Otto CM. Physical examination in valvular aortic stenosis: correlation with stenosis severity and prediction of clinical outcome. Am Heart J1999; 137:298\u2013306.","DOI":"10.1053\/hj.1999.v137.95496"},{"key":"key\n\t\t\t\t20170413030547_R9","doi-asserted-by":"crossref","unstructured":"Aronow WS, Kronzon I. Prevalence and severity of valvular aortic stenosis determined by Doppler echocardiography and its association with echocardiographic and electrocardiographic left ventricular hypertrophy and physical signs of aortic stenosis in elderly patients. Am J Cardiol1991; 67:776\u20137.","DOI":"10.1016\/0002-9149(91)90542-S"},{"key":"key\n\t\t\t\t20170413030547_R10","doi-asserted-by":"crossref","unstructured":"Hoagland PM, Cook EF, Wynne J, Goldman L. Value of noninvasive testing in adults with suspected aortic stenosis. Am J Med1986; 80:1041\u20139.","DOI":"10.1016\/0002-9343(86)90663-7"},{"key":"key\n\t\t\t\t20170413030547_R11","doi-asserted-by":"crossref","unstructured":"Lombard JT, Seltzer A. Valvular aortic stenosis. A clinical and haemodynamic profile of patients. Ann Int Med1987; 106:292\u20138.","DOI":"10.7326\/0003-4819-106-2-292"},{"key":"key\n\t\t\t\t20170413030547_R12","doi-asserted-by":"crossref","unstructured":"Mautner GC, Mautner SL, Cannon RO, Hunsberger SA, Roberts WC. Clinical factors useful in predicting aortic valve structure in patients >40 years of age with isolated valvular aortic stenosis. Am J Cardiol1993; 72:194\u20138.","DOI":"10.1016\/0002-9149(93)90159-A"},{"key":"key\n\t\t\t\t20170413030547_R13","unstructured":"Wren C, Petch MC. Calcific aortic stenosis. J R Coll Physicians Lond1983; 17:192\u20135."},{"key":"key\n\t\t\t\t20170413030547_R14","unstructured":"Wood P. Diseases of the Heart and Circulation. Eyre and Spottiswoode, 1950."},{"key":"key\n\t\t\t\t20170413030547_R15","doi-asserted-by":"crossref","unstructured":"Come PC, Riley MF, Ferguson JF, Morgan JP, McKay RG. Prediction of severity of aortic stenosis: accuracy of multiple noninvasive parameters. Am J Med1988; 85:29\u201337.","DOI":"10.1016\/0002-9343(88)90499-8"},{"key":"key\n\t\t\t\t20170413030547_R16","doi-asserted-by":"crossref","unstructured":"Fink JC, Schmid CH, Selker HP. A decision aid for referring patients with systolic murmurs for echocardiography. J Gen Int Med1994; 9:479\u201384.","DOI":"10.1007\/BF02599215"},{"key":"key\n\t\t\t\t20170413030547_R17","doi-asserted-by":"crossref","unstructured":"Mangione S, Nieman LZ. Cardiac auscultatory skills of internal medicine and family practice trainees. A comparison of diagnostic proficiency. JAMA1997; 278:717\u201322.","DOI":"10.1001\/jama.278.9.717"},{"key":"key\n\t\t\t\t20170413030547_R18","doi-asserted-by":"crossref","unstructured":"Morgan DJR, Hall RJC. Occult aortic stenosis as a cause of intractable heart failure. BMJ1979; 1:784\u20137.","DOI":"10.1136\/bmj.1.6166.784"},{"key":"key\n\t\t\t\t20170413030547_R19","doi-asserted-by":"crossref","unstructured":"Bonow R, Carabello B, de Leon A. ACC\/AHA guidelines for the management of patients with valvular disease. Executive summary. Circulation1998; 98:1949\u201384.","DOI":"10.1161\/01.CIR.98.18.1949"},{"key":"key\n\t\t\t\t20170413030547_R20","unstructured":"Prendergast BD, Banning AP, Hall RJC. Valvular heart disease. Investigation and management. Recommendations of a working group of the British Cardiac Society and The Research Unit of the Royal College of Physicians. London, RCP, 1996."}],"container-title":["QJM: An International Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/qjmed\/article-pdf\/93\/10\/685\/12817677\/930685.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T03:50:03Z","timestamp":1583293803000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/qjmed\/article-lookup\/doi\/10.1093\/qjmed\/93.10.685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":20,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2000,10]]},"published-print":{"date-parts":[[2000,10]]}},"URL":"https:\/\/doi.org\/10.1093\/qjmed\/93.10.685","relation":{},"ISSN":["1460-2393","1460-2725"],"issn-type":[{"value":"1460-2393","type":"electronic"},{"value":"1460-2725","type":"print"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}