{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:18:40Z","timestamp":1793319520318,"version":"4.5.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,27]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>B-lines have been associated with adverse clinical outcomes in patients with heart failure (HF) when found at hospital discharge or during outpatient visits. Whether lung ultrasound (LUS) assessed B-lines may predict in-hospital mortality in patients with acute HF is still undetermined.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To evaluate the association between B-lines on admission and in-hospital mortality among patients admitted with acute HF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Hand-held LUS was used to examine patients with acute HF. LUS was performed in eight chest zones with a pocket ultrasound device and analyzed offline. The association between B-lines and in-hospital mortality was assessed using Cox regression models.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We included 62 patients with median age 56\u2009years, 69.4% men, and median left ventricle ejection fraction 25%. The sum of B-lines ranged from 0 to 53 (median 6.5). An optimal receiver operating characteristic-determined cut-off of \u226519 B-lines demonstrated a sensitivity of 57% and a specificity of 86% (area under the curve 0.788) for in-hospital mortality. The incremental prognostic value of LUS when compared with lung crackles or peripheral edema by integrated discrimination improvement was 12.96% (95% CI: 7.0\u201318.8, P\u2009=\u20090.02). Patients with \u226519 B-lines had a 4-fold higher risk of in-hospital mortality (HR 4.38; 95% CI: 1.37\u201313.95, P\u2009&amp;lt;\u20090.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In patients admitted with acute HF, point-of-care LUS measurements of pulmonary congestion (B-lines) are associated with in-hospital mortality.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/qjmed\/hcaa298","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T19:12:37Z","timestamp":1603221157000},"page":"111-116","source":"Crossref","is-referenced-by-count":13,"title":["Point-of-care lung ultrasound predicts in-hospital mortality in acute heart failure"],"prefix":"10.1093","volume":"114","author":[{"given":"D","family":"Araiza-Garaygordobil","sequence":"first","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4865-4869","authenticated-orcid":false,"given":"R","family":"Gopar-Nieto","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Mart\u00ednez-Amezcua","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Wolfe Street 615, Baltimore 21205, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cabello-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n de Salud en el Trabajo, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauht\u00e9moc 330, Doctores, Cuauht\u00e9moc 06720, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Manzur-Sandoval","sequence":"additional","affiliation":[{"name":"Cardiovascular Critical Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Garc\u00eda-Cruz","sequence":"additional","affiliation":[{"name":"Cardiovascular Critical Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"De la Fuente-Mancera","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Mart\u00ednez-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Luna-Carrera","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Lerma-Landeros","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F M","family":"Guti\u00e9rrez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Gonz\u00e1lez-Pacheco","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Instituto Nacional de Cardiolog\u00eda \u201cIgnacio Ch\u00e1vez\u201d, Juan Badiano 1, Belisario Dom\u00ednguez Secci\u00f3n XVI, Tlalpan 14030, M\u00e9xico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"Brise\u00f1o-De la Cruz","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, 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