{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T01:46:08Z","timestamp":1776044768499,"version":"3.50.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,1]]},"DOI":"10.1093\/qjmed\/hcaf249","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:14:34Z","timestamp":1760703274000},"page":"245-246","source":"Crossref","is-referenced-by-count":0,"title":["Sequential tofacitinib and low-dose interleukin-2 therapy: reassessing biomarkers and mechanistic gaps in alopecia areata"],"prefix":"10.1093","volume":"119","author":[{"given":"Shiuan-Chih","family":"Chen","sequence":"first","affiliation":[{"name":"Institute of Medicine, College of Medicine, Chung Shan Medical University , Taichung,","place":["Taiwan"]},{"name":"School of Medicine, College of Medicine, Chung Shan Medical University , Taichung,","place":["Taiwan"]},{"name":"Department of Family and Community Medicine, Chung Shan Medical University Hospital , Taichung,","place":["Taiwan"]},{"name":"Department of Family and Community Medicine, Chung Shan Medical University Hospital Chung Shing Branch , Taichung,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Ti","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine, Chung Shan Medical University , Taichung,","place":["Taiwan"]},{"name":"Department of Internal Medicine, Chung Shan Medical University Hospital , Taichung,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"2026041221155850500_hcaf249-B1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcaf221","article-title":"Sequential immunotherapy with tofacitinib and low-dose IL-2 induces sustained remission in alopecia areata: a proof-of-concept monocentric study","author":"Huang","year":"2025","journal-title":"QJM"},{"key":"2026041221155850500_hcaf249-B2","doi-asserted-by":"crossref","first-page":"1111547","DOI":"10.3389\/fimmu.2023.1111547","article-title":"The potential of regulatory T cell-based therapies for alopecia areata","volume":"14","author":"Wan","year":"2023","journal-title":"Front Immunol"},{"key":"2026041221155850500_hcaf249-B3","doi-asserted-by":"crossref","first-page":"1581976","DOI":"10.3389\/fimmu.2025.1581976","article-title":"Correlation between increased total serum IgE levels and clinical features in alopecia areata patients","volume":"16","author":"Sun","year":"2025","journal-title":"Front Immunol"},{"key":"2026041221155850500_hcaf249-B4","doi-asserted-by":"crossref","first-page":"eadh0152","DOI":"10.1126\/sciimmunol.adh0152","article-title":"Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche","volume":"9","author":"Cohen","year":"2024","journal-title":"Sci Immunol"},{"key":"2026041221155850500_hcaf249-B5","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1001\/jamadermatol.2024.2734","article-title":"Baricitinib withdrawal and retreatment in patients with severe alopecia areata: the BRAVE-AA1 randomized clinical trial","volume":"160","author":"King","year":"2024","journal-title":"JAMA Dermatol"}],"container-title":["QJM: An International Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/qjmed\/advance-article-pdf\/doi\/10.1093\/qjmed\/hcaf249\/64739043\/hcaf249.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/qjmed\/article-pdf\/119\/3\/245\/64739043\/hcaf249.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/qjmed\/article-pdf\/119\/3\/245\/64739043\/hcaf249.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T01:16:01Z","timestamp":1776042961000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/qjmed\/article\/119\/3\/245\/8292675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,17]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,10,17]]},"published-print":{"date-parts":[[2026,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/qjmed\/hcaf249","relation":{},"ISSN":["1460-2725","1460-2393"],"issn-type":[{"value":"1460-2725","type":"print"},{"value":"1460-2393","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,3]]},"published":{"date-parts":[[2025,10,17]]}}}