{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:24:02Z","timestamp":1793996642575,"version":"4.8.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hospital admission for acute deep vein thrombosis (DVT) was historically considered mandatory, reflecting the therapeutic limitations and safety concerns of previous decades. Over time, advances in anticoagulant therapy, diagnostic strategies and healthcare organization have profoundly changed this paradigm. Low-molecular-weight heparins and, more recently, direct oral anticoagulants have enabled effective and safe outpatient treatment for a large proportion of patients. Nonetheless, hospitalization remains common in clinical practice, often driven by habit, uncertainty, or organizational barriers rather than clear evidence-based indications. This perspective summarizes the evolution of DVT management, integrates contemporary evidence and guidance, and proposes a pragmatic framework to identify patients who still benefit from hospitalization. The emphasis is on physician-led decision-making that integrates thrombotic and bleeding risk, comorbidities, the extent of thrombosis and social and system-level factors. Rather than considering hospitalization as the default treatment, we advocate a deliberate, personalized triage approach aligned with contemporary internal medicine practice.<\/jats:p>","DOI":"10.1093\/qjmed\/hcag156","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T19:08:45Z","timestamp":1781550525000},"page":"657-660","source":"Crossref","is-referenced-by-count":0,"title":["Acute deep vein thrombosis: who still needs hospital admission?"],"prefix":"10.1093","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7166-5630","authenticated-orcid":false,"given":"Nicola","family":"Mumoli","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Ospedale di Circolo , Busto Arsizio, VA,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6905-3467","authenticated-orcid":false,"given":"Francesco","family":"Cei","sequence":"additional","affiliation":[{"name":"1st Internal Medicine, Department of Multidimensional Medicine, San Giuseppe Hospital , Empoli, FI,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1646-2275","authenticated-orcid":false,"given":"Lucia","family":"Colavolpe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Ospedale di Circolo , Busto Arsizio, VA,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"2026110614242940300_hcag156-B1","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S0140-6736(60)92299-6","article-title":"Anticoagulant drugs in the treatment of pulmonary embolism","volume":"1","author":"Barritt","year":"1960","journal-title":"Lancet"},{"key":"2026110614242940300_hcag156-B2","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1067\/mva.2000.110352","article-title":"Compression and walking versus bed rest in the treatment of proximal deep venous thrombosis with low molecular weight heparin","volume":"32","author":"Partsch","year":"2000","journal-title":"J Vasc Surg"},{"key":"2026110614242940300_hcag156-B3","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3138\/physio.61.3.133","article-title":"Ambulation after deep vein thrombosis: a systematic review","volume":"61","author":"Anderson","year":"2009","journal-title":"Physiother Can"},{"key":"2026110614242940300_hcag156-B4","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1056\/NEJM199204093261502","article-title":"Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis","volume":"326","author":"Hull","year":"1992","journal-title":"N Engl J Med"},{"key":"2026110614242940300_hcag156-B5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0140-6736(92)91054-C","article-title":"Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis","volume":"339","author":"Prandoni","year":"1992","journal-title":"Lancet"},{"key":"2026110614242940300_hcag156-B6","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1056\/NEJM199603143341102","article-title":"Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. 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