{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T02:25:36Z","timestamp":1782354336674,"version":"3.54.5"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Coronary Artery Disease-Reporting and Data System (CAD-RADS) is a standardized reporting system that offers a structured method for interpreting and reporting results obtained through coronary computed tomography angiography. It has been deemed useful in the prognostication of patients with suspected coronary artery disease (CAD).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>The present meta-analysis sought to assess the prognostic value of CAD-RADS in individuals with suspected CAD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>We conducted a systematic search of the electronic databases of PubMed, Web of Science Core Collection, Cochrane advanced search, and EMBASE. A random-effects model was implemented to evaluate the pooled hazard ratio (HR) for each CAD-RADS category and area under the receiver operating characteristics curve for predicting major adverse cardiovascular events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Data from 37 596 coronary computed tomography angiography examinations from 13 studies were analyzed. During follow-up, 2,536 (6.7%) adverse events were observed. Pooled HRs for prediction of adverse events were significant for all CAD-RADS categories, with incremental increase in HRs with progressively higher categories. For prediction of all-cause mortality, all categories except CAD-RADS 1 showed significant HR compared with CAD-RADS 0. Combination of CAD-RADS to conventional clinical risk factors and CAC resulted in a high predictive capacity for adverse events (pooled area under the receiver operating characteristics curve: 0.82 ([95% confidence interval, 0.73-0.91]).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The CAD-RADS category imparts information on the CAD severity and shows incremental increase in HR for adverse events with progressively higher categories, especially beyond CAD-RADS4b.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/radadv\/umae007","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:13:55Z","timestamp":1712016835000},"source":"Crossref","is-referenced-by-count":5,"title":["Prognostic significance of CAD-RADS for patients with suspected coronary artery disease: A systematic review and meta-analysis"],"prefix":"10.1093","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7545-0669","authenticated-orcid":false,"given":"Shingo","family":"Kato","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Yokohama City University Graduate School of Medicine , Yokohama 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7409-3308","authenticated-orcid":false,"given":"Mai","family":"Azuma","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kanagawa Cardiovascular and Respiratory Center , Yokohama 236-0051, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8200-0340","authenticated-orcid":false,"given":"Nobuyuki","family":"Horita","sequence":"additional","affiliation":[{"name":"Chemotherapy Center, Yokohama City University Graduate School of Medicine , Yokohama 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1723-1724","authenticated-orcid":false,"given":"Daisuke","family":"Utsunomiya","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Yokohama City University Graduate School of Medicine , Yokohama 236-0004, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,1]]},"reference":[{"issue":"10","key":"2024051416012960600_umae007-B1","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.jacc.2020.06.076","article-title":"Coronary computed tomography angiography from clinical uses to emerging technologies: JACC state-of-the-art review","volume":"76","author":"Abdelrahman","year":"2020","journal-title":"J Am Coll Cardiol."},{"issue":"14","key":"2024051416012960600_umae007-B2","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/j.jacc.2011.03.068","article-title":"The 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